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European Union cosmetic ingredient regulations

EU Cosmetics Regulation 1223/2009 annexes and the CosIng discovery database.

Regulator
European Commission
Source language
English and EU languages
Coverage version
Regulation (EC) 1223/2009 consolidated to 1 May 2026

What this list is

The EU list is not one list. Regulation 1223/2009 splits substances across five annexes that answer different questions, and reading the wrong one is the most common way to get an EU answer wrong.

  • Annex II prohibits 1,739 substances outright.
  • Annex III permits 373 substances only within stated limits, product types and warnings.
  • Annexes IV, V and VI are positive lists: 154 colourants, 54 preservatives, 33 UV filters.
  • For those three categories, absence from the annex means not permitted — the opposite of Annex II's logic.
  • CosIng is a discovery database, not the law; the annexes as published are.

Most markets on this site publish one list. The EU publishes five, and they do not work the same way. Annex II names substances that may not be used at all. Annex III names substances that may be used, but only within a concentration limit, for stated product types, and often with a warning that must appear on the label. Annexes IV, V and VI are positive lists for colourants, preservatives and UV filters.

That last distinction reverses the logic and catches people out. For a substance in general, absence from Annex II is not permission — nothing has been decided about it. For a preservative, absence from Annex V is a decision: it may not be used as a preservative in a cosmetic product. The same silence means opposite things depending on which annex you are reading.

CosIng is worth naming separately, because it is what most searches land on. It is the Commission's database for finding ingredients and their annex references, and it is genuinely useful for that. It is not the legal text. When CosIng and the published annex disagree — usually because an amendment has come into force and the database has not caught up — the annex governs.

An Annex III entry is also more than a number. The limit, the product-type condition and the warning text travel together, and quoting the concentration without the condition it applies to produces an answer that is right about the figure and wrong about the product.

Checked against

Official ingredient records

2353 matching records
Annex VBinding EU regulation

PHENOXYISOPROPANOL

Only for rinse-off products

Source reference: Annex V, entry 43 · 09/11/2010

Annex VBinding EU regulation

DIMETHYL OXAZOLIDINE

pH > 6

Source reference: Annex V, entry 45 · 16/10/2010

Annex VBinding EU regulation

DIAZOLIDINYL UREA

Source reference: Annex V, entry 46 · 02/08/2021

Annex VBinding EU regulation

GLUTARAL

Not to be used in aerosols (sprays)

Source reference: Annex V, entry 48 · 25/10/2010

Annex VBinding EU regulation

7-ETHYLBICYCLOOXAZOLIDINE

Not to be used in oral products and in products applied on mucous membranes

Source reference: Annex V, entry 49 · 02/08/2021

Annex VBinding EU regulation

chlorphenesin

Source reference: Annex V, entry 50 · 16/10/2010

Annex VBinding EU regulation

SODIUM HYDROXYMETHYLGLYCINATE

Not to be used if the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, if the mixture as placed on the market is ≥ 0,1 % w/w

Source reference: Annex V, entry 51 · 04/11/2021

Annex VBinding EU regulation

SILVER CHLORIDE

20% AgCl (w/w) on TiO2. Not to be used in products for children under 3 years of age, in oral products and in eye and lip products

Source reference: Annex V, entry 52 · 16/10/2010

Annex VBinding EU regulation

Benzethonium Chloride

a) Rinse-off products b) Leave-on products other than oral products

Source reference: Annex V, entry 53 · 16/10/2010

Annex VBinding EU regulation

BENZYLHEMIFORMAL

Rinse-off products

Source reference: Annex V, entry 55 · 02/08/2021

Annex VBinding EU regulation

IODOPROPYNYL BUTYLCARBAMATE

Not to be used in oral and lip products a) Not to be used in products for children under 3 years of age, except in bath products / shower gels and shampoos b) Not to be used in body lotion and body cream (13) b) and c) Not to be used in products for children …

Source reference: Annex V, entry 56 · 16/10/2010

Annex VBinding EU regulation

Ethyl-N-alpha-dodecanoyl-L-arginate hydrochloride

(a) Not to be used in preparations for children under 10 years of age (b) Not to be used in lip products, oral products (other than mouthwashes), and spray products

Source reference: Annex V, entry 58 · 27/07/2020

Annex VBinding EU regulation

HYDROXYETHOXY­PHENYL BUTANONE, HEPB

Allowed for use as a preservative in rinse off, oral care and leave-on cosmetic products at a maximum concentration of 0,7 % in ready for use preparation.

Source reference: Annex V, entry 60 · 27/07/2020

Annex VBinding EU regulation

o-Phenylphenol, Sodium o-Phenylphenate

When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by i…

Source reference: Annex V, entry 7 · 15/01/2026

Annex VIBinding EU regulation

OCTOCRYLENE

a) Propellant spray products b) Other products

Source reference: Annex VI, entry 10 · 31/01/2023

Annex VIBinding EU regulation

PEG-25 PABA

Source reference: Annex VI, entry 13 · 15/10/2010

Annex VIBinding EU regulation

Ethylhexyl Triazone

Source reference: Annex VI, entry 15 · 15/10/2010

Annex VIBinding EU regulation

METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL (NANO)

Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — Purity ≥ 98,5 %, with 2,2′-methylene-bis- (6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) iso…

Source reference: Annex VI, entry 23a · 06/08/2020

Annex VIBinding EU regulation

Polysilicone-15

Source reference: Annex VI, entry 26 · 15/10/2010

Annex VIBinding EU regulation

TITANIUM DIOXIDE

Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance with Annex III, No 321. For the product types under letter (c) of column (f) in Annex III, No 321, the maximum concentration in rea…

Source reference: Annex VI, entry 27 · 21/06/2021

Annex VIBinding EU regulation

TRIS-BIPHENYL TRIAZINE / TRIS-BIPHENYL TRIAZINE (NANO)

Not to be used in sprays. Only nanomaterials having the folloing characteristics are allowed: - Median primary particle size >80 nm; - Purity ≥ 98%; - Uncoated

Source reference: Annex VI, entry 29 · 10/10/2016

Annex VIBinding EU regulation

HOMOSALATE

From 1 January 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 July 2025 cosmetic products containing that substance and not complying with the conditions shall not be made…

Source reference: Annex VI, entry 3 · 11/11/2022

Annex VIBinding EU regulation

ZINC OXIDE

Source reference: Annex VI, entry 30 · 13/09/2016

Annex VIBinding EU regulation

ZINC OXIDE (NANO)

Source reference: Annex VI, entry 30a · 01/03/2019

Annex VIBinding EU regulation

PHENYLENE BIS-DIPHENYLTRIAZINE

Not to be used in applications that may lead to exposure of the end user's lungs by inhalation.

Source reference: Annex VI, entry 31 · 22/09/2021

Annex VIBinding EU regulation

Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate

- Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation - Do not use with nitrosating agents - Maximum nitrosamine content: 50 μg/kg - Keep in nitrite-free containers

Source reference: Annex VI, entry 32 · 24/11/2020

Annex VIBinding EU regulation

BIS-(DIETHYLAMINOHYDROXYBENZOYL BENZOYL) PIPERAZINE (NANO)

Only nanomaterials having the following characteristics are allowed: — Purity ≥ 97 % —Median particle size D50 (50 % of the number below this diameter): ≥ 50 nm of number size distribution. Not to be used in applications that may lead to exposure of the end u…

Source reference: Annex VI, entry 34 · 27/11/2022

Annex VIBinding EU regulation

BENZOPHENONE-3

a) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 5,5 %. b) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 1,7 %.

Source reference: Annex VI, entry 4 · 29/07/2024

Market coverage contract

Complete annex dataset
Included scope
Annexes II–VI: prohibited and restricted substances, colourants, preservatives and UV filters.
If no match is found
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.

Complete verification checklist

  1. Confirm the exact INCI/CAS/EC identity.
  2. Review every matching Annex II–VI row and its conditions.
  3. Check SCCS opinions, CMR/nanomaterial rules and later amendments.
  4. Verify product classification, claims, labelling and responsible-person duties.

How European Union differs from other markets

Comparing this market's imported rules against every other market's for the same substance. A market with no imported rule for a substance is left out of that comparison rather than treated as permitting it.

Official sources and legal role

PubChem PUG-View annotations

Attributed physical-property, hazard, environmental, use and literature annotations for uniquely matched PubChem compounds

Legal meaning: Scientific context aggregated by PubChem; individual values retain their named depositor or publication source

EMBL-EBI ChEBI 2.0

Curated definitions, chemical classes, roles, names, relationships and cross-references

Legal meaning: Curated scientific ontology; not a cosmetics permission or prohibition list

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Legal meaning: Identity registry only; UNII availability does not imply FDA review or approval

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Legal meaning: Independent expert review considered by FDA; not a government approval or binding market rule

EU Safety Gate cosmetic product alerts

Published cosmetic product alerts, notifying country, risk, product identifiers and corrective measures

Legal meaning: Official market-surveillance alerts; not proof that a named ingredient caused an incident

Available language: English and EU languages

What this market page can answer

Source and authority

Identify the official material and the regulator responsible for it: European Commission.

Language and scope

See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English and EU languages.

Evidence status

Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.

How to verify an ingredient for this market

  1. Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
  2. Open each official source above and check the current version, product scope, concentration limits and required warnings.
  3. Confirm effective dates and whether an English text is official, reviewed or only contextual.
  4. Treat a missing local match as unknown, never as permission or a safety conclusion.