What is CAS 118-56-9 for HOMOSALATE?

CAS 118-56-9 is the unique numerical identifier assigned to HOMOSALATE by the Chemical Abstracts Service. It is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports.

How is the maximum concentration of HOMOSALATE calculated in a finished product?

The maximum concentration of 7,34 % applies to the substance in the ready-to-use cosmetic product. When supplied as part of a blend or mixture, the calculation must account for contributions from all sources in the formulation.

Annex VI Entry 3 11/11/2022

HOMOSALATE

Q: Is HOMOSALATE an approved UV filter in the EU?

Yes. HOMOSALATE is listed in Annex VI of EU Cosmetics Regulation 1223/2009 as a permitted UV filter. It may be used at concentrations up to the specified maximum in the ready-to-use product.

Q: How do I check if my product formula contains HOMOSALATE?

Use the INCI Checker tool on CosIng Checker to paste your full ingredient list and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records.

Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester / Homosalate

HOMOSALATE appears in Annex VI as a positive-list UV filter entry for EU cosmetics. Maximum concentration in this record: 7,34 %.

Permitted UV filter— Annex VI, EU Regulation 1223/2009

Max conc.: 7,34 %

Entry: 3

Reading this entry

Homosalate was cut back in 2022 to face products only, at 7.34%, after the SCCS reassessed it. Body sunscreens that once used it as a bulk filter no longer have an entry to sit in.

7.34%, and only in face products, excluding propellant sprays.
Body sunscreens and spray formats are outside the permitted product type entirely.
1 January 2025 stops non-compliant products being placed on the market; 1 July 2025 stops them being made available.
The previous limit was 10% across products, so a reformulation is not a small adjustment.

The number changed and the product scope changed with it, and the second is the harder constraint. Homosalate may be used at up to 7.34% in face products, excluding propellant sprays. It has no permitted use in a body sunscreen at all, which is the format that previously accounted for most of its volume.

The route here is the usual one for a UV filter: an SCCS reassessment concluded that the earlier 10% was not supported for the exposure pattern of a whole-body product, and the entry was narrowed to a use the evidence covered. That is worth knowing when comparing markets, because a filter reduced in the EU on exposure grounds often remains at its old limit elsewhere.

The two dates work as they always do. From 1 January 2025 a non-compliant product may not be placed on the Union market by its manufacturer or importer; from 1 July 2025 it may not be made available by anyone, including a retailer holding stock bought before the first date.

Checked against

Regulation (EC) No 1223/2009, Annex VI (EUR-Lex)

Chemical identity and properties

PubChem 2D chemical structure for CAS 118-56-9

CAS 118-56-9PubChem CID 8362

Homosalate

2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid. — ChEBI

IUPAC name: (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate

Molecular formula: C16H22O3
Molecular weight: 262.34 g/mol
Exact mass: 262.15689456 Da
XLogP3: 5.0
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Homomenthyl salicylateHeliophan3,3,5-Trimethylcyclohexyl 2-hydroxybenzoateHomosalatoHomosalatumBenzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl esterSalicylic Acid 3,3,5-Trimethylcyclohexyl EsterNSC-164918

16 more reported names

V06SV4M95SSunscreen SKINCAREBULUBIU ADVANCEDRefChem:55307dAlba Vegan Fresh Sun StickdAlba Vegan Essence SunscreenIlluminating Daily MoisturizerdAlba Vegan Tone-Up SunscreenSun Protection Facial SPF 50Facial Primer Protector SPF 50Bulubiu Face Sunscreen SKINCAREBULUBIU WEIGHTLESS MOISTURIZERILLUMINATING DAILY MOISTURIZER SPF 30Eight Hour Cream Targeted Sun Defense SPF 50Clean Fresh Sunblock Sunscreen SPF 30 ContinuousHomosalate, Ethylhexyl Methoxycinnamate,Titanium Dioxide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:91642
ChEMBL:CHEMBL1377575
EPA DTXSID:DTXSID1026241
PubMed:39159849
PubMed:38381479
PubMed:28551711
PubMed:24004914
PubMed:23769903
PubMed:23062433
PubMed:22884209
PubMed:22749456
PubMed:22669305
PubMed:22612478
PubMed:22214440
PubMed:21872075

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match8362

Attributed physical-property, hazard, environmental and use annotations.

Boiling Point: 322 to 329 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals

Density: 1.045 at 77 °F (NTP, 1992) - Denser than water; will sink Source: CAMEO Chemicals

Flash Point: greater than 200 °F (NTP, 1992) Source: CAMEO Chemicals

Physical Description: 3,3,5-trimethylcyclohexylsalicylate appears as viscous or light yellow to slightly tan liquid or oil. (NTP, 1992) Source: CAMEO Chemicals

Solubility: Insoluble (<1 mg/ml at 79 °F) (NTP, 1992) Source: CAMEO Chemicals

First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals

Note: This chemical does not meet GHS hazard criteria for 67% (152 of 227) of all reports. Source: European Chemicals Agency (ECHA)
Signal: Warning Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H315 (16.7%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (16.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H361d (11.5%): Suspected of damaging the unborn child [Warning Reproductive toxicity]; H410 (11.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P203, P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 227 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 152 of 227 reports by companies.; There are 3 notifications provided by 75 of 227 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Industry Uses: Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

7,34 %

Product type

Face products with the exception of propellent spray products

Other restrictions

From 1 January 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 July 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

INCI glossary name

HOMOSALATE

Chemical name

Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester / Homosalate

Chemical / IUPAC name

Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester / Homosalate

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

Identified ingredients

HOMOSALATE

Key data

CAS

118-56-9

204-260-8

Annex

Entry number

Inventory links for HOMOSALATE

Inventory Restriction reference

Ref 34299

HOMOSALATE

CAS: 118-56-9

EC: 204-260-8

Direct matches are limited for this record, so nearby entries from Annex VI are shown as well.

Annex VI 2