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InventoryRef 8715912/06/2014

TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE

diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide

TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE is linked to 1 EU annex record on this page.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited + Restricted
Open this evidence		2English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence		1English
ASEANEvidence linked
Restricted
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilEvidence linked
Prohibited
Open this evidence		1Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 75980-60-8
CAS 75980-60-8PubChem CID 166480

2,4,6-Trimethylbenzoyl diphenylphosphine oxide

IUPAC name
diphenylphosphoryl-(2,4,6-trimethylphenyl)methanone
Molecular formula
C22H21O2P
Molecular weight
348.4 g/mol
Exact mass
348.12791691 Da
XLogP3
5.0
Topological polar surface area
34.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxidePhosphine oxide, diphenyl(2,4,6-trimethylbenzoyl)-EINECS 278-355-8B9EIM2D97Xtrimethylbenzoyl diphenylphosphine oxideCHIVACURE TPODOUBLECURE TPOADDITOL TPO
16 more reported names
GENOCURE TPOMethanone, (diphenylphosphinyl)(2,4,6-trimethylphenyl)-EC 278-355-8(2,4,6-trimethylbenzoyl)diphenylphosphine oxide(DIPHENYLPHOSPHINYL)(2,4,6-TRIMETHYLPHENYL)METHANONERefChem:442966TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE [INCI]278-355-8(Diphenylphosphoryl)(mesityl)methanone2,4,6-trimethyl benzoyldiphenyl phosphine oxide2,4,6-Trimethylbenzoyldiphenylphosphine oxidediphenyl(2,4,6-trimethylbenzoyl)phosphineoxidediphenyl (2,4,6-trimethylbenzoyl)phosphine oxideUNII-B9EIM2D97Xdiphenylphosphino[(2,4,6-trimethylphenyl)carbonyl]-1-one2,4,6-Trimethylbenzoylphenyl phosphinate, (Diphenylphosphoryl)(mesityl)methanone, (2,4,6-Trimethylbenzoyl)diphenylphosphine oxide
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE

INCI name

TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE

Description

diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide

Record provenance

Inventory reference
87159
Imported identity
TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE
Source update
12/06/2014
European Commission CosIng source notes

Key data

CAS
75980-60-8
EC
278-355-8
Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29270 · TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 7 markets that hold a rule for it.

prohibited
European UnionGreat BritainBrazilSaudi Arabia
restricted
New ZealandASEANIndia

Great Britain holds more than one rule for this substance, so its position there depends on the use.

See every substance the markets disagree about

Ingredients with overlapping formulation functions

TRIMETHOXYSILYL DIMETHICONESKIN CONDITIONING
TRIMETHYL HYDROXYMETHYL CYCLOHEXANOLSKIN CONDITIONING
TRIMETHYL PENTAPHENYL TRISILOXANESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
TRIMETHYL PHYTOSPHINGOSINE IODIDEHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING
TRIMETHYLCYCLOHEXYL BUTYLCARBAMATESKIN CONDITIONING
TRIMETHYLOLPROPANE TRICAPRYLATE/TRICAPRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
TRIMETHYLOLPROPANE TRICOCOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT
TRIMETHYLOLPROPANE TRIETHYLHEXANOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE appears in the CosIng inventory

The CosIng inventory lists TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE carries the following function designation(s):

CAS 75980-60-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE

This page combines the CosIng inventory entry for TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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