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Annex VI Entry 20 08/03/2011

ETHYLHEXYL SALICYLATE

2-Ethylhexyl salicylate / Octisalate)

ETHYLHEXYL SALICYLATE appears in Annex VI as a positive-list UV filter entry for EU cosmetics. Maximum concentration in this record: 5%.

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Permitted UV filter— Annex VI, EU Regulation 1223/2009
Max conc.: 5%
Entry: 20

Chemical identity and properties

PubChem 2D chemical structure for CAS 118-60-5
CAS 118-60-5PubChem CID 8364

2-Ethylhexyl salicylate

Ethylhexyl salicylate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid. — ChEBI

IUPAC name
2-ethylhexyl 2-hydroxybenzoate
Molecular formula
C15H22O3
Molecular weight
250.33 g/mol
Exact mass
250.15689456 Da
XLogP3
5.7
Topological polar surface area
46.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

OctisalateBenzoic acid, 2-hydroxy-, 2-ethylhexyl esterEscalolSalicylic Acid 2-Ethylhexyl EsterOctisalatoNSC-461514X49Y0596WOCTYLSALICYLATE
16 more reported names
octisalatumTanning OilRefChem:856053Arizona Sun Tanning Oil SPF 3204-263-4Ethylhexyl salicylateSunarome WMOEthyl hexyl salicylateSunarome OUvinulUSAF DO-11Neo HeliopanSalicylic acid, 2-ethylhexyl esterDermoblock OSNSC 46151OCTISALATE [INN]
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8364

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 0.8% (14 of 1669) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (84.7%): Causes skin irritation [Warning Skin corrosion/irritation]; H410 (14.4%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P273, P280, P302+P352, P321, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1669 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 14 of 1669 reports by companies.; There are 8 notifications provided by 1655 of 1669 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Ethylhexyl Salicylate... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

5%

INCI glossary name

ETHYLHEXYL SALICYLATE

Chemical name

2-Ethylhexyl salicylate / Octisalate)

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
118-60-5
EC
204-263-4
Annex
VI
Entry number
20

Inventory links for ETHYLHEXYL SALICYLATE

Direct matches are limited for this record, so nearby entries from Annex VI are shown as well.

Annex VI 13
Nearby record in the same annex

PEG-25 PABA

CAS: 116242-27-4

What Annex VI means for ETHYLHEXYL SALICYLATE

ETHYLHEXYL SALICYLATE is an approved UV filter listed in Annex VI of EU Cosmetics Regulation 1223/2009. Only UV filters included in this positive list may be used to provide UV protection in EU cosmetic products.

The maximum permitted concentration specified in this entry applies to the ready-to-use product. Some UV filters are restricted to specific application types or require label warnings.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Concentration in ready-to-use product must not exceed: 5%
  • Check whether the UV filter is approved for both leave-on and rinse-off applications.

Frequently asked questions

Yes. ETHYLHEXYL SALICYLATE is listed in Annex VI of EU Cosmetics Regulation 1223/2009 as a permitted UV filter. It may be used at concentrations up to the specified maximum in the ready-to-use product.

CAS 118-60-5 is the unique numerical identifier assigned to ETHYLHEXYL SALICYLATE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 5% applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex VI record ETHYLHEXYL SALICYLATE

This page summarizes one Annex VI record for ETHYLHEXYL SALICYLATE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex VI conditions for ETHYLHEXYL SALICYLATE, but confirm any final regulatory decision against the current official annex wording and source files.

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