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Annex V Entry 51 04/11/2021

SODIUM HYDROXYMETHYLGLYCINATE

Sodium hydroxymethylamino acetate

SODIUM HYDROXYMETHYLGLYCINATE appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: 0.5%.

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Permitted preservative— Annex V, EU Regulation 1223/2009
Max conc.: 0.5%
Entry: 51

Record details

Maximum concentration

0.5%

Other restrictions

Not to be used if the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, if the mixture as placed on the market is ≥ 0,1 % w/w

INCI glossary name

SODIUM HYDROXYMETHYLGLYCINATE

Chemical name

Sodium hydroxymethylamino acetate

Chemical / IUPAC name

Sodium N-(hydroxymethyl)glycinate /Sodium hydroxymethylamino acetate

Regulatory information

Regulation

(EU) 2021/1902

SCCS opinions

Identified ingredients

Key data

CAS
70161-44-3
EC
274-357-8
Annex
V
Entry number
51

Inventory links for SODIUM HYDROXYMETHYLGLYCINATE

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 50
Nearby record in the same annex

chlorphenesin

CAS: 104-29-0
EC: 203-192-6
Annex V 52
Nearby record in the same annex

SILVER CHLORIDE

CAS: 7783-90-6
EC: 232-033-3
Annex V 48
Nearby record in the same annex

GLUTARAL

CAS: 111-30-8
EC: 203-856-5

What Annex V means for SODIUM HYDROXYMETHYLGLYCINATE

SODIUM HYDROXYMETHYLGLYCINATE is an approved preservative listed in Annex V of EU Cosmetics Regulation 1223/2009. Only substances on this positive list may be used as cosmetic preservatives in the EU.

Each preservative entry specifies maximum permitted concentrations and applicable product scope. Concentrations must not exceed the listed maximum. Some preservatives require warning statements on the product label.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Use concentration must not exceed: 0.5%
  • Verify the preservative is effective at the permitted concentration for your matrix.

Frequently asked questions

Yes. SODIUM HYDROXYMETHYLGLYCINATE is listed in Annex V of EU Cosmetics Regulation 1223/2009 as a permitted preservative. It may be used in cosmetics up to the maximum concentration specified above, within the permitted product scope.

CAS 70161-44-3 is the unique numerical identifier assigned to SODIUM HYDROXYMETHYLGLYCINATE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.5% applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex V record SODIUM HYDROXYMETHYLGLYCINATE

This page summarizes one Annex V record for SODIUM HYDROXYMETHYLGLYCINATE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex V conditions for SODIUM HYDROXYMETHYLGLYCINATE, but confirm any final regulatory decision against the current official annex wording and source files.

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