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Annex V Entry 54 16/10/2010

BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

Benzalkonium chloride, bromide and saccharinate (10)

BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: 0.1% (as benzalkonium chloride).

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Permitted preservative— Annex V, EU Regulation 1223/2009
Max conc.: 0.1% (as benzalkonium chloride)
Entry: 54

Chemical identity and properties

PubChem 2D chemical structure for CAS 8001-54-5
CAS 8001-54-5PubChem CID 3014024

Benzalkonium Chloride

On the basis of the data presented in this report, the CIR Expert Panel concludes that Benzalkonium Chloride, at concentrations up to 0.1% free, active ingredient, is safe as a cosmetic ingredient as presently used. Note: In 2006, the CIR Expert Panel considered available new data on this ingredient and confirmed the above conclusion. — Cosmetic Ingredient Review (CIR)

IUPAC name
benzyl-dimethyl-tridecylazanium chloride
Molecular formula
C22H40ClN
Molecular weight
354.0 g/mol
Exact mass
353.2849280 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
2
Defined stereocentres
0

Also known as

pentoniumAlpagelleZephiranBenzalkonii chloridumCloruro de benzalconioChlorure de benzalkoniumNSC-758480CHEBI:3020
16 more reported names
FundamentalsGreenberryProsanitizeShieldplexViraxshieldAquacilBecauseCaseysLavenderCleanseCompanionDaranjoDermacideDisinallEnuclenHandsoapHandwash
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 91080-29-4
CAS 91080-29-4PubChem CID 23705

Benzododecinium Bromide

Benzododecinium bromide is the organic bromide salt of benzododecinium. It is a cationic surfactant that has antispetic and disinfectant properties. It has a role as a surfactant, an antiseptic drug and a disinfectant. It is a quaternary ammonium salt and an organic bromide salt. It contains a benzododecinium. — ChEBI

IUPAC name
benzyl-dodecyl-dimethylazanium bromide
Molecular formula
C21H38BrN
Molecular weight
384.4 g/mol
Exact mass
383.21876 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
2
Defined stereocentres
0

Also known as

SterinolN-Benzyl-N,N-dimethyldodecan-1-aminium bromideBacfor BLLauralkonium bromideSinnoquat BL 80Sinnoquat BL 95Benzenemethanaminium, N-dodecyl-N,N-dimethyl-, bromideAmmonyl BR 1244
16 more reported names
Caswell No. 416BDodecyl dimethyl benzyl ammonium bromideN-Dodecyl-N,N-dimethylbenzenemethanaminium bromideIRY12B2TQ6Dimethyl laurylbenzene ammonium bromideAmmonium, benzyldodecyldimethyl-, bromideEINECS 230-698-4UNII-IRY12B2TQ6EPA Pesticide Chemical Code 069123CHEBI:167207Bromek dwumetylolaurylobenzyloamoniowyBENZODODECINIUM BROMIDE (II)BENZODODECINIUM BROMIDE [II]BENZODODECINIUM BROMIDE (MART.)BENZODODECINIUM BROMIDE [MART.]RefChem:54497
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

0.1% (as benzalkonium chloride)

Warnings

Avoid contact with eyes

INCI glossary name

BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

Chemical name

Benzalkonium chloride, bromide and saccharinate (10)

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
8001-54-5/ 63449-41-2 / 91080-29-4 / 68989-01-5 / 68424-85-1 / 68391-01-5 / 61789-71-7 / 85409-22-9
EC
264-151-6 / 293-522-5 / 273-545-7 / 270-325-2 / 269-919-4 / 263-080-8 / 287-089-1
Annex
V
Entry number
54

Inventory links for BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

Inventory Restriction reference
Ref 32129

BENZALKONIUM CHLORIDE

CAS: 63449-41-2 / 68391-01-5 / 68424-85-1 / 85409-22-9
EC: 264-151-6 / 269-919-4 / 270-325-2 / 287-089-1

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 52
Nearby record in the same annex

SILVER CHLORIDE

CAS: 7783-90-6
EC: 232-033-3
Annex V 50
Nearby record in the same annex

chlorphenesin

CAS: 104-29-0
EC: 203-192-6
Annex V 48
Nearby record in the same annex

GLUTARAL

CAS: 111-30-8
EC: 203-856-5

What Annex V means for BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE is an approved preservative listed in Annex V of EU Cosmetics Regulation 1223/2009. Only substances on this positive list may be used as cosmetic preservatives in the EU.

Each preservative entry specifies maximum permitted concentrations and applicable product scope. Concentrations must not exceed the listed maximum. Some preservatives require warning statements on the product label.

This record is linked to 13 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Use concentration must not exceed: 0.1% (as benzalkonium chloride)
  • Verify the preservative is effective at the permitted concentration for your matrix.
  • Apply required label warning statement.

Frequently asked questions

Yes. BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE is listed in Annex V of EU Cosmetics Regulation 1223/2009 as a permitted preservative. It may be used in cosmetics up to the maximum concentration specified above, within the permitted product scope.

CAS 8001-54-5/ 63449-41-2 / 91080-29-4 / 68989-01-5 / 68424-85-1 / 68391-01-5 / 61789-71-7 / 85409-22-9 is the unique numerical identifier assigned to BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.1% (as benzalkonium chloride) applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex V record BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE

This page summarizes one Annex V record for BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex V conditions for BENZALKONIUM CHLORIDE / BENZALKONIUM BROMIDE / BENZALKONIUM SACCHARINATE, but confirm any final regulatory decision against the current official annex wording and source files.

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