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InventoryRef 3148511/09/2017

2-AMINO-3-HYDROXYPYRIDINE

2-aminopyridin-3-ol

2-AMINO-3-HYDROXYPYRIDINE is linked to 1 EU annex record on this page. Inventory note: Annex III/211 - Directive 2012/21/EU.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence		1English
ASEANEvidence linked
Restricted
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Prohibited + Restricted
Open this evidence		2Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 16867-03-1
CAS 16867-03-1PubChem CID 28114

2-Amino-3-Hydroxypyridine

2-amino-3-hydroxypyridine is a monohydroxypyridine and an aminopyridine. — ChEBI

IUPAC name
2-aminopyridin-3-ol
Molecular formula
C5H6N2O
Molecular weight
110.11 g/mol
Exact mass
110.048012819 Da
XLogP3
0.1
Topological polar surface area
59.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

2-Amino-3-pyridinol3-Pyridinol, 2-amino-3-Hydroxy-2-pyridinamine3-HYDROXY-2-AMINOPYRIDINE3-Pyridinol, 2-aminoP8740PEW4BJAROCOL 2A3HPRODOL 2A3PYR
16 more reported names
NSC-136806RefChem:85129240-886-82-amino-pyridin-3-ol2-Amino-3-pyridolPaliperidone Impurity 252-amino-3-hydroxy-pyridine2-AMINO-3-HYDROXY PYRIDINEUNII-P8740PEW4BEINECS 240-886-8NSC 136806AI3-610612-amino-3hydroxypyridine2-amino-3 -hydroxypyridineBMTSZVZQNMNPCT-UHFFFAOYSA-CHEBI:195501
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 2-AMINO-3-HYDROXYPYRIDINE

INCI name

2-AMINO-3-HYDROXYPYRIDINE

Description

2-aminopyridin-3-ol

Record provenance

Inventory reference
31485
Imported identity
2-AMINO-3-HYDROXYPYRIDINE
Source update
11/09/2017
European Commission CosIng source notes

Key data

CAS
16867-03-1
EC
240-886-8
Restriction
Annex III/211 - Directive 2012/21/EU
Function
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#186 · 2-AMINO-3-HYDROXYPYRIDINE

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 7 markets that hold a rule for it.

prohibited
South Korea
restricted
European UnionGreat BritainNew ZealandASEANIndiaSaudi Arabia

South Korea holds more than one rule for this substance, so its position there depends on the use.

See every substance the markets disagree about

Ingredients with overlapping formulation functions

2,6-DIMETHYL-P-PHENYLENEDIAMINEHAIR DYEING
2,6-DIMETHYL-P-PHENYLENEDIAMINE HCLHAIR DYEING
2,7-NAPHTHALENEDIOLHAIR DYEING
2-(2,2-DIMETHOXY)ETHOXY-P-PHENYLENEDIAMINEHAIR DYEING
2-AMINO-3-NITROPHENOLHAIR DYEING
2-AMINO-4-HYDROXYETHYLAMINOANISOLEHAIR DYEING
2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATEHAIR DYEING
2-AMINO-4-NITROPHENOLHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How 2-AMINO-3-HYDROXYPYRIDINE appears in the CosIng inventory

The CosIng inventory lists 2-AMINO-3-HYDROXYPYRIDINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-AMINO-3-HYDROXYPYRIDINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-AMINO-3-HYDROXYPYRIDINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for 2-AMINO-3-HYDROXYPYRIDINE reads: "Annex III/211 - Directive 2012/21/EU". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, 2-AMINO-3-HYDROXYPYRIDINE carries the following function designation(s):

CAS 16867-03-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for 2-AMINO-3-HYDROXYPYRIDINE

This page combines the CosIng inventory entry for 2-AMINO-3-HYDROXYPYRIDINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research 2-AMINO-3-HYDROXYPYRIDINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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