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InventoryRef 3148717/11/2016

2-AMINO-4-HYDROXYETHYLAMINOANISOLE

2-[(3-amino-4-methoxyphenyl)amino]ethanol

2-AMINO-4-HYDROXYETHYLAMINOANISOLE is linked to 1 EU annex record on this page. Inventory note: III/245.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence
1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence
1English
ASEANEvidence linked
Restricted
Open this evidence
1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Prohibited + Restricted
Open this evidence
2Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence
1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence
1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 83763-47-7
CAS 83763-47-7PubChem CID 3019283

1-Methoxy-2-amino-4-(2-hydroxyethylamino)benzene

The CIR Expert Panel concluded that 2-amino-4-hydroxyethylaminoanisole and 2-amino-4-hydroxyethylaminoanisole sulfate are safe for use in oxidative hair dye formulations. Were the free base (2-amino-4-hydroxyethylaminoanisole) to be used in the future, the expectation is that it would be used at concentrations similar to the sulfate salt. The Expert Panel cautions that these ingredients should not be used in hair dye products in which N-nitroso compounds may be formed. Cosmetic Ingredient Review (CIR)

IUPAC name
2-(3-amino-4-methoxyanilino)ethanol
Molecular formula
C9H14N2O2
Molecular weight
182.22 g/mol
Exact mass
182.105527694 Da
XLogP3
0.5
Topological polar surface area
67.5 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

2-Amino-4-hydroxyethylaminoanisole0NK0KYZ30RRefChem:85205280-733-22-((3-Amino-4-methoxyphenyl)amino)ethanol2-[(3-AMINO-4-METHOXYPHENYL)AMINO]ETHANOLEthanol, 2-[(3-amino-4-methoxyphenyl)amino]-Ethanol, 2-((3-amino-4-methoxyphenyl)amino)-
11 more reported names
EINECS 280-733-2UNII-0NK0KYZ30R2-((3-amino-4-methoxyphenyl)amino)ethan-1-olSBUMIGFDXJIPLE-UHFFFAOYSA-N2-(3-amino-4-methoxy-anilino)ethanol2-amino-4-(2-hydroxyethylamino)anisole2-(3-Amino-4-methoxyanilino)ethan-1-ol2-amino-4-(2'-hydroxyethylamino)anisoleDS-17936CS-01505771-METHOXY-2-AMINO-4-(.BETA.-HYDROXYETHYLAMINO)BENZENE
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE

INCI name

2-AMINO-4-HYDROXYETHYLAMINOANISOLE

Description

2-[(3-amino-4-methoxyphenyl)amino]ethanol

Record provenance

Inventory reference
31487
Imported identity
2-AMINO-4-HYDROXYETHYLAMINOANISOLE
Source update
17/11/2016
European Commission CosIng source notes

Key data

Restriction
III/245
Function
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 7 markets that hold a rule for it.

prohibited
South Korea
restricted
European UnionGreat BritainNew ZealandASEANIndiaSaudi Arabia

South Korea holds more than one rule for this substance, so its position there depends on the use.

See every substance the markets disagree about

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How 2-AMINO-4-HYDROXYETHYLAMINOANISOLE appears in the CosIng inventory

The CosIng inventory lists 2-AMINO-4-HYDROXYETHYLAMINOANISOLE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

2-AMINO-4-HYDROXYETHYLAMINOANISOLE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

2-AMINO-4-HYDROXYETHYLAMINOANISOLE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE reads: "III/245". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, 2-AMINO-4-HYDROXYETHYLAMINOANISOLE carries the following function designation(s):

CAS 83763-47-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE

This page combines the CosIng inventory entry for 2-AMINO-4-HYDROXYETHYLAMINOANISOLE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research 2-AMINO-4-HYDROXYETHYLAMINOANISOLE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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