CHOLECALCIFEROL
CHOLECALCIFEROL is linked to 1 EU annex record on this page. Inventory note: II/335.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Evidence linked Prohibited Open this evidence | 1 | English |
| Canada | Evidence linked Restricted Open this evidence | 1 | English and French |
| New Zealand | Evidence linked Prohibited Open this evidence | 1 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Evidence linked Prohibited Open this evidence | 1 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Evidence linked Prohibited Open this evidence | 1 | Portuguese with INCI crosswalks |
| India | Evidence linked Prohibited Open this evidence | 1 | English and Hindi |
| Saudi Arabia | Evidence linked Prohibited Open this evidence | 1 | Arabic and English |
Chemical identity and properties
Vitamin D3
Calciol is a hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone. It has a role as a geroprotector and a human metabolite. It is a steroid hormone, a secondary alcohol, a seco-cholestane, a hydroxy seco-steroid and a member of D3 vitamins. — ChEBI
- IUPAC name
- (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
- Molecular formula
- C27H44O
- Molecular weight
- 384.6 g/mol
- Exact mass
- 384.339216023 Da
- XLogP3
- 7.9
- Topological polar surface area
- 20.2 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 5
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:28940
- ChEMBL:CHEMBL1042
- EPA DTXSID:DTXSID6026294
- PubMed:40633737
- PubMed:39671242
- PubMed:38588969
- PubMed:38191086
- PubMed:38081571
- PubMed:37244046
- PubMed:36813254
- PubMed:36745886
- PubMed:36603807
- PubMed:36066700
- PubMed:35395231
- PubMed:34051273
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for CHOLECALCIFEROL
INCI name
CHOLECALCIFEROL
Record provenance
- Inventory reference
- 84502
- Imported identity
- CHOLECALCIFEROL
- Source update
- 15/10/2010
Annex records for CHOLECALCIFEROL
Ergocalciferol (INN) and Cholecalciferol (vitamins D2 and D3)
Key data
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 8 markets that hold a rule for it.
- prohibited
- European UnionGreat BritainNew ZealandChinaBrazilIndiaSaudi Arabia
- restricted
- Canada
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How CHOLECALCIFEROL appears in the CosIng inventory
The CosIng inventory lists CHOLECALCIFEROL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
CHOLECALCIFEROL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for CHOLECALCIFEROL
This page combines the CosIng inventory entry for CHOLECALCIFEROL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research CHOLECALCIFEROL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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