What does the restriction note for THIRAM mean?

The restriction field for THIRAM reads: II/162. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 137-26-8?

CAS 137-26-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains THIRAM?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8465515/10/2010

THIRAM

THIRAM is linked to 1 EU annex record on this page. Inventory note: II/162.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Evidence linked Restricted Open this evidence	1	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	2	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	2	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 137-26-8

CAS 137-26-8PubChem CID 5455

Thiram

Thiram is an organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. It has a role as an antibacterial drug, an antiseptic drug and an antifungal agrochemical. It contains a dimethyldithiocarbamate. It is functionally related to a dimethyldithiocarbamic acid. — ChEBI

IUPAC name: dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate

Molecular formula: C6H12N2S4
Molecular weight: 240.4 g/mol
Exact mass: 239.98833309 Da
XLogP3: 1.7
Topological polar surface area: 121.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Tetramethylthiuram disulfideThiuramTMTDRezifilmPomarsolThirameArasanFernasan

16 more reported names

NobecutanNormersanAapirolPuralinSpotreteThiosanThirasanTetrathiuram disulfideTetramethylthiuramFalitiramFormalsolHexathirKregasanMercuramSadoplonTetrasipton

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:9495
ChEMBL:CHEMBL120563
EPA DTXSID:DTXSID5021332
PubMed:38593872
PubMed:38568856
PubMed:36965607
PubMed:36842454
PubMed:36288636
PubMed:36183428
PubMed:33715048
PubMed:32870474
PubMed:32553615
PubMed:32194361
PubMed:31652400
PubMed:30889403

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for THIRAM

INCI name

THIRAM

Record provenance

Inventory reference: 84655
Imported identity: THIRAM
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for THIRAM

Annex II Restriction reference

Entry 162

Disulfiram (INN); thiram (ISO) (INN)

CAS: 97-77-8 / 137-26-8

EC: 202-607-8 / 205-286-2

Key data

CAS

137-26-8

205-286-2

Restriction

II/162

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28773 · THIRAM

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 10 markets that hold a rule for it.

prohibited: European Union Great Britain New Zealand ASEAN China South Korea Brazil India Saudi Arabia
restricted: Canada

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Ingredients with overlapping formulation functions

THIABENDAZOLEANTIMICROBIAL

THIANTHOLANTIMICROBIAL, SKIN CONDITIONING

THIOCTAMIDOETHYL DIMETHYLAMINE MALEATEANTIMICROBIAL, ANTIOXIDANT, BLEACHING, SKIN CONDITIONING

THIOUREAANTIMICROBIAL, HUMECTANT

THUJA ORIENTALIS EXTRACTANTIMICROBIAL, ASTRINGENT, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

THUJA ORIENTALIS LEAF OILANTIMICROBIAL; ANTIOXIDANT; SKIN PROTECTING

THUJA ORIENTALIS LEAF WATERANTIMICROBIAL; ANTIOXIDANT; SKIN PROTECTING

THUJOPSIS DOLABRATA STEM OILANTIMICROBIAL, DEODORANT, FRAGRANCE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How THIRAM appears in the CosIng inventory

The CosIng inventory lists THIRAM as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

THIRAM is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

THIRAM appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for THIRAM reads: "II/162". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, THIRAM carries the following function designation(s):

ANTIMICROBIAL

CAS 137-26-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for THIRAM

This page combines the CosIng inventory entry for THIRAM with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research THIRAM and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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