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InventoryRef 3740629/07/2020

QUATERNIUM-15

Methenamine 3-chloroallylochloride

QUATERNIUM-15 is linked to 2 EU annex records on this page.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence
2English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence
2English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Prohibited
Open this evidence
2English
ASEANEvidence linked
Prohibited
Open this evidence
2English and national languages
ChinaEvidence linked
Prohibited
Open this evidence
1Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Restricted
Open this evidence
1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilEvidence linked
Prohibited
Open this evidence
1Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence
1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence
2Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 4080-31-3
CAS 4080-31-3PubChem CID 20011

Quaternium 15

1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride is a cream-colored powder. (NTP, 1992) CAMEO Chemicals

IUPAC name
1-(3-chloroprop-2-enyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride
Molecular formula
C9H16Cl2N4
Molecular weight
251.15 g/mol
Exact mass
250.0752019 Da
Topological polar surface area
9.7 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Quaternium-15CHEBI:59607Dowicil 100N-(3-Chloroallyl)hexaminium chlorideDowicide Q1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chlorideCinartc 200Dowco 184
16 more reported names
E40U03LEM0NSC-1729711-(3-chloroallyl)-hexaminium chlorideRefChem:9304403,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride1-(3-chloroprop-2-en-1-yl)-1,3,5,7-tetraazatricyclo(3.3.1.1^(3,7))decan-1-ium chloride1-(3-chloroprop-2-en-1-yl)-1,3,5,7-tetraazatricyclo(3.3.1.13,7)decan-1-ium chloride223-805-0CTACHexamethylenetetramine chloroallyl chloride1-(CIS-3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIA-ADAMANTANE CHLORIDE1-?(3-?Chloroallyl)?-?1,?3,?5,?7-?tetraazaadamantan-?1-?ium ChlorideUKHVLWKBNNSRRR-UHFFFAOYSA-MEpitope ID:1318021-(3-chloroallyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane;chloride1-(3-Chloroprop-2-en-1-yl)-1,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decan-1-ium chloride
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 51229-78-8
CAS 51229-78-8PubChem CID 6435993

cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride

Quaternium-15 is a quaternary ammonium salt used as a preservative in many cosmetics and industrial substances. It acts as a formaldehyde releaser. It can cause contact dermatitis in sensitive individuals. It's toxicity is also due to it's ability to react and release formaldehyde and nitrosamines, both of which are believed to be carcinogenic. (L1890, L1897) Toxin and Toxin Target Database (T3DB)

IUPAC name
1-[(Z)-3-chloroprop-2-enyl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride
Molecular formula
C9H16Cl2N4
Molecular weight
251.15 g/mol
Exact mass
250.0752019 Da
Topological polar surface area
9.7 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Chloroallyl methenamine chlorideQuaternium-15 cis-formUNII-LIT014L4RHLIT014L4RHCOSEPT 200EC 426-020-3QUATERNIUM-15 CIS-FORM [II]QUATERNIUM-15 CIS-FORM [MI]
16 more reported names
1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANE CHLORIDE, CIS-QUATERNIUM-15 CIS-FORM (II)3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.13,7)DECANE, 1-((2Z)-3-CHLORO-2-PROPEN-1-YL)-, CHLORIDE (1:1)RefChem:126386426-020-3Dowicil 2001-((Z)-3-Chloroallyl)-1,3,5,7-tetraazaadamantan-1-ium chloridecis-N-(3-Chloroallyl) hexaminium chlorideHexamethylenetetramine cis-chloroallyl chlorideC9H16Cl2N41-(cis-3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloridecis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantantane Chloride1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, cis form3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-((2Z)-3-chloro-2-propenyl)-, chloride3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride, (Z)-1-[(2Z)-3-CHLOROPROP-2-EN-1-YL]-1,3,5,7-TETRAAZATRICYCLO[3.3.1.1(3),?]DECAN-1-IUM CHLORIDE
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for QUATERNIUM-15

INCI name

QUATERNIUM-15

Description

Methenamine 3-chloroallylochloride

Record provenance

Inventory reference
37406
Imported identity
QUATERNIUM-15
Source update
29/07/2020
European Commission CosIng source notes

Key data

CAS
4080-31-3 / 51229-78-8
EC
223-805-0 / 426-020-3
Restriction
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 9 markets that hold a rule for it.

prohibited
European UnionGreat BritainNew ZealandASEANChinaBrazilIndiaSaudi Arabia
restricted
South Korea

See every substance the markets disagree about

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How QUATERNIUM-15 appears in the CosIng inventory

The CosIng inventory lists QUATERNIUM-15 as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

QUATERNIUM-15 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

QUATERNIUM-15 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, QUATERNIUM-15 carries the following function designation(s):

CAS 4080-31-3 / 51229-78-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for QUATERNIUM-15

This page combines the CosIng inventory entry for QUATERNIUM-15 with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research QUATERNIUM-15 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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