ASEAN cosmetic ingredient regulations

4-(3-ethoxy-4-hydroxyphenyl)butan-2-one Hydroxyethoxyphenyl Butanone CAS No. 569646-79-3

CAS 569646-79-3 · EC 933-435-8

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.7 %

Source:ASEAN Annex VI, reference 60 · version 2026-1 · source checked 2026-08-30

4-(4-Methoxyphenyl)-3-butene-2-one, when used as a fragrance

CAS 943-88-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 443 · version 2026-1 · source checked 2026-08-30

4-(Phenylazo)resorcinol (Solvent Orange 1; CI 11920) and its

CAS 2051-85-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1343 · version 2026-1 · source checked 2026-08-30

4-Amino-2-nitrophenol

CAS 119-34-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 412 · version 2026-1 · source checked 2026-08-30

4-Amino-3-fluorophenol

CAS 399-95-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1242 · version 2026-1 · source checked 2026-08-30

4-Amino-3-hydroxytoluene when used as a substance in hair

CAS 2835-98-5 · EC 220-620-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1643 · version 2026-1 · source checked 2026-08-30

4-Amino-3-nitrophenol CAS No. 610-81-1

CAS 610-81-1 · EC 210-236-8

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: a) Hair dye substance in oxidative hair dye products · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% · (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 215 · version 2026-1 · source checked 2026-08-30

4-Amino-5-hydroxy-3-(4- nitrophenylazo)-6- (phenylazo)-2,7- naphthalenedisulfonic acid, disodium salt Acid Black 1 CAS No 1064-48-8

CAS 1064-48-8 · EC 213-903-1

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · 0.5% · The direction for use “wear suitable gloves” must be included in label or leaflet text. · Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 310 · version 2026-1 · source checked 2026-08-30

4-Amino-m-cresol 4-Amino-m-cresol CAS No 2835-99-6

CAS 2835-99-6 · EC 220-621-2

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5 % The direction for use “wear suitable gloves” must be included in label or leaflet text. · The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 246 · version 2026-1 · source checked 2026-08-30

4-Aminoazobenzene

CAS 60-09-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 990 · version 2026-1 · source checked 2026-08-30

4-Aminobenzenesulfonic acid and its salts, when used as a

CAS 121-57-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1257 · version 2026-1 · source checked 2026-08-30

4-Aminobenzoic acid and its esters, with the free amino group

CAS 94-09-7 · EC 202-303-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 167 · version 2026-1 · source checked 2026-08-30

4-Aminophenol p-Aminophenol CAS No 123-30-8

CAS 123-30-8 · EC 204-616-2

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.9 % · The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows”

Source:ASEAN Annex III, reference 296 · version 2026-1 · source checked 2026-08-30

4-Aminosalicylic acid and its salts

CAS 65-49-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 31 · version 2026-1 · source checked 2026-08-30

4-Benzyloxyphenol and 4-ethoxyphenol

CAS 103-16-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 178 · version 2026-1 · source checked 2026-08-30

4-Chloro-2-aminophenol, when used as a substance in hair dye

CAS 95-85-2 · EC 202-458-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1219 · version 2026-1 · source checked 2026-08-30

4-Chloro-3,5-xylenol CAS No. 88-04-0

CAS 88-04-0

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.5%

Source:ASEAN Annex VI, reference 26 · version 2026-1 · source checked 2026-08-30

4-Chloro-m-cresol CAS No. 59-50-7

CAS 59-50-7 · EC 200-431-6

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.2% · Prohibited in products intended to come into contact with mucous membranes

Source:ASEAN Annex VI, reference 24 · version 2026-1 · source checked 2026-08-30

4-Cyano-2,6-diiodophenyl octanoate

CAS 3861-47-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1063 · version 2026-1 · source checked 2026-08-30

4-Diethylamino-o-toluidine and its salts, when used as a substance in hair dye products

CAS 148-71-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1310 · version 2026-1 · source checked 2026-08-30

4-Dimethylaminobenzoate of ethyl-2-hexyl (octyl dimethyl PABA) CAS No. 21245-02-3

CAS 21245-02-3 · EC 244-289-3

ASEAN Annex VII lists this record among UV filters allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 8%

Source:ASEAN Annex VII, reference 21 · version 2026-1 · source checked 2026-08-30

4-Ethoxy-m-phenylenediamine and its salts

CAS 67801-06-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 406 · version 2026-1 · source checked 2026-08-30

4-Ethylamino-3-nitrobenzoic acid (N-Ethyl-3-Nitro PABA) and its

CAS 2788-74-1 · EC 412-090-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1290 · version 2026-1 · source checked 2026-08-30

4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate CAS No 1603-02-7

CAS 1603-02-7 · EC 216-500-9

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows.”

Source:ASEAN Annex III, reference 317 · version 2026-1 · source checked 2026-08-30

4-Hydroxybenzoic acid and its Methyl- and Ethyl- esters, and their salts (INCI) 4-Hydroxybenzoic acid; CAS No. 99-96-7; Methylparaben; CAS No. 99-76-3; potassium ethylparaben; CAS No. 36457-19-9; potassium paraben; CAS No. 16782-08-4 sodium methylparaben; CAS No. 5026-62-0; sodium ethylparaben; CAS No. 35285-68-8; ethylparaben; CAS No. 120-47-8; sodium paraben; CAS No. 114-63-6; potassium methylparaben; CAS No. 26112-07- 2; calcium paraben; CAS No. 69959-44-0;

4-Hydroxybenzoic acid and its Methyl- and Ethyl- esters, and their salts (INCI) 4-Hydroxybenzoic acid; CAS No. 99-96-7; Methylparaben; CAS No. 99-76-3; potassium ethylparaben; CAS No. 36457-19-9; potassium paraben; CAS No. 16782-08-4 sodium methylparaben;

CAS 99-96-7; 99-76-3; 36457-19-9; 16782-08-4; 5026-62-0; 35285-68-8; 120-47-8; 114-63-6; 26112-07-2; 69959-44-0 · EC 202-804-9

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.4% (as acid) for single ester 0.8% (as acid) for mixtures of esters

Source:ASEAN Annex VI, reference 12 · version 2026-1 · source checked 2026-08-30

4-Hydroxyindole, when used as a substance in hair dye

CAS 2380-94-1 · EC 219-177-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1220 · version 2026-1 · source checked 2026-08-30

4-Isopropyl-m-cresol CAS No. 3228-02-2

CAS 3228-02-2 · EC 221-761-2

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.1%

Source:ASEAN Annex VI, reference 38 · version 2026-1 · source checked 2026-08-30

4-Mesyl-2-nitrotoluene

CAS 1671-49-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1499 · version 2026-1 · source checked 2026-08-30

4-Methoxytoluene-2,5-diamine and its HCl salt, when used as a

CAS 56496-88-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1221 · version 2026-1 · source checked 2026-08-30

4-Methyl-m-phenylene diisocyanate

CAS 584-84-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1119 · version 2026-1 · source checked 2026-08-30

4-Methyl-m-phenylenediamine and its salts

CAS 95-80-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 364 · version 2026-1 · source checked 2026-08-30

4-Methylbenzylidene Camphor; 3-(4'-methylbenzylidene)-camphor

CAS 36861-47-9; 38102-62-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1723 · version 2026-1 · source checked 2026-08-30

4-Nitro-1,2-phenylenediamine 4-Nitro-o-Phenylenediamine CAS No 99-56-9

CAS 99-56-9 · EC 202-766-3

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.1% The direction for use “wear suitable gloves” must be included in label or leaflet text. · The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 265 · version 2026-1 · source checked 2026-08-30

4-Nitro-m-phenylenediamine and its salts, when used as a

CAS 5131-58-8 · EC 225-876-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1282 · version 2026-1 · source checked 2026-08-30

4-Nitrobiphenyl

CAS 92-93-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 686 · version 2026-1 · source checked 2026-08-30

4-Nitrosophenol

CAS 104-91-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 995 · version 2026-1 · source checked 2026-08-30

4-Phenylazophenylene-1,3-diamine citrate hydrochloride

CAS 5909-04-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 81 · version 2026-1 · source checked 2026-08-30

4-Phenylbut-3-en-2-one

CAS 122-57-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 356 · version 2026-1 · source checked 2026-08-30

4-Vinylcyclohexene

CAS 100-40-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1569 · version 2026-1 · source checked 2026-08-30

4-[(2-Hydroxyethyl)amino]-3- nitrophenol 3-Nitro-p-hydroxyethylaminophenol CAS No 65235-31-6

CAS 65235-31-6 · EC 265-648-0

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · b) 1.85 % · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.0 % For (a) and (b): • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg(21) • Keep in nitrite- free containers The direction for use “wear suitable gloves” must be included in label or leaflet text. · a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows (b) Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 250 · version 2026-1 · source checked 2026-08-30

4-[(2-Nitrophenyl)amino]phenol HC Orange No 1 CAS No 54381-08-7

CAS 54381-08-7 · EC 259-132-4

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · 1.0% · The direction for use “wear suitable gloves” must be included in label or leaflet text.

Source:ASEAN Annex III, reference 269 · version 2026-1 · source checked 2026-08-30

4-[(3-Chlorophenyl)(1H-imidazol-1-yl)methyl]-1,2-

CAS 159939-85-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1516 · version 2026-1 · source checked 2026-08-30

4-[(4-Aminophenyl)(4-iminocyclohexa-2,5-dien-1-

CAS 3248-93-9; 632-99-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1329 · version 2026-1 · source checked 2026-08-30

4-[(4-Ethoxyphenyl)azo]naphthol (Solvent Red 3; CI 12010) and

CAS 6535-42-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1344 · version 2026-1 · source checked 2026-08-30

4-[(4-Nitrophenyl)azo]aniline (Disperse Orange 3) and its salts,

CAS 730-40-5 · EC 211-984-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1281 · version 2026-1 · source checked 2026-08-30

4-[(tetrahydro-2H-pyran-2-yl)oxy]phenol (Deoxyarbutin,

CAS 53936-56-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1657 · version 2026-1 · source checked 2026-08-30

4-[4-(1,3-Dihydroxyprop-2-yl)phenylamino]-1,8-dihydroxy-5-

CAS 114565-66-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1002 · version 2026-1 · source checked 2026-08-30

4-methylpentan-2-one; isobutyl methyl ketone (MIBK)

CAS 08-10-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1689 · version 2026-1 · source checked 2026-08-30

4-o-Tolylazo-o-toluidine

CAS 97-56-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 989 · version 2026-1 · source checked 2026-08-30

4-tert-Butyl-3-methoxy-2,6-dinitrotoluene (Musk ambrette)

CAS 83-66-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 414 · version 2026-1 · source checked 2026-08-30