What does the restriction note for ISOPROPYL CRESOLS mean?

The restriction field for ISOPROPYL CRESOLS reads: V/38. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 3228-02-2?

CAS 3228-02-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ISOPROPYL CRESOLS?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3468716/10/2010

ISOPROPYL CRESOLS

4-Isopropyl-m-cresol

ISOPROPYL CRESOLS is linked to 1 EU annex record on this page. Inventory note: V/38.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Positive-list entry with conditions Open this evidence	1	English and EU languages
Great Britain	Evidence linked Permitted list with conditions Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Evidence linked Permitted list with conditions Open this evidence	1	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Restricted Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 3228-02-2

CAS 3228-02-2PubChem CID 18597

3-Methyl-4-isopropylphenol

4-Isopropyl-3-methylphenol is an alkylbenzene. — ChEBI

IUPAC name: 3-methyl-4-propan-2-ylphenol

Molecular formula: C10H14O
Molecular weight: 150.22 g/mol
Exact mass: 150.104465066 Da
XLogP3: 3.0
Topological polar surface area: 20.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

4-Isopropyl-3-methylphenolo-CYMEN-5-OL3-Methyl-4-(1-methylethyl)phenolH41B6Q1I9LNORO-X Foaming HandSoapNSC-62111RefChem:55740Biosol

16 more reported names

4-Isopropyl-m-cresolp-ThymolPhenol, 3-methyl-4-(1-methylethyl)-o-Cymen-5y-ol3-methyl-4-(propan-2-yl)phenolisopropylmethylphenol4-Isopropyl-5-methylphenol4-isopropyl-3-methyl-phenolBiosal (antibacterial)1-Hydroxy-3-methyl-4-isopropylbenzeneBRN 1364028DS-6343BP-12478M0409EN300-20058Frecide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:34429
EPA DTXSID:DTXSID10186026
PubMed:22438954
PubMed:21762159
PubMed:21762158
PubMed:21762157
PubMed:21762156
PubMed:21762154
PubMed:21762153
PubMed:21762152
PubMed:21762151
PubMed:21762150
PubMed:21762148
PubMed:16835130

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ISOPROPYL CRESOLS

INCI name

ISOPROPYL CRESOLS

Description

4-Isopropyl-m-cresol

Record provenance

Inventory reference: 34687
Imported identity: ISOPROPYL CRESOLS
Source update: 16/10/2010

European Commission CosIng source notes

Annex records for ISOPROPYL CRESOLS

Annex V Restriction reference

Entry 38

O-CYMEN-5-OL

CAS: 3228-02-2

EC: 221-761-7

Key data

CAS

3228-02-2

221-761-2

Restriction

V/38

Function

PRESERVATIVE: Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#13841 · ISOPROPYL CRESOLS

The 4 markets that hold a rule for this substance do not classify it the same way.

restricted: South Korea
permitted on a positive list: European Union Great Britain ASEAN

See every substance the markets disagree about

Ingredients with overlapping formulation functions

IMIDAZOLIDINYL UREAPRESERVATIVE

IODOPROPYNYL BUTYLCARBAMATEPRESERVATIVE

ISOBUTYL BENZOATEFRAGRANCE, PRESERVATIVE, SOLVENT

ISOPROPYL BENZOATEFRAGRANCE, PRESERVATIVE

ISOPROPYLPARABENPRESERVATIVE

LACTOBACILLUS/RADISH ROOT FERMENT FILTRATEPRESERVATIVE

LAURALKONIUM BROMIDEANTISTATIC, PRESERVATIVE

LAURALKONIUM CHLORIDEANTISTATIC, PRESERVATIVE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ISOPROPYL CRESOLS appears in the CosIng inventory

The CosIng inventory lists ISOPROPYL CRESOLS as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ISOPROPYL CRESOLS is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ISOPROPYL CRESOLS appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ISOPROPYL CRESOLS reads: "V/38". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ISOPROPYL CRESOLS carries the following function designation(s):

PRESERVATIVE

CAS 3228-02-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ISOPROPYL CRESOLS

This page combines the CosIng inventory entry for ISOPROPYL CRESOLS with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ISOPROPYL CRESOLS and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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