ASEAN cosmetic ingredient regulations

3-Diethylaminopropyl cinnamate

CAS 538-66-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 130 · version 2026-1 · source checked 2026-08-30

3-Ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine

CAS 143860-04-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1163 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-4-(phenylazo)-2-naphthoic acid and its calcium salt

CAS 27757-79-5; 6371-76-2 · EC 228-899-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1331 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-4-[(2-hydroxynaphthyl)azo]-7-nitronaphthalene-1-

CAS 16279-54-2; 5610-64-0 · EC 227-029-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1323 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-

CAS 6535-46-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1346 · version 2026-1 · source checked 2026-08-30

3-Imidazol-4-ylacrylic acid and its ethyl ester (Urocanic acid)

CAS 104-98-3 · EC 203-258-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 418 · version 2026-1 · source checked 2026-08-30

3-Methyl -1- phenyl -5-pyrazolone Phenyl Methyl Pyrazolone CAS No. 89-25-8

CAS 89-25-8 · EC 201-891-0

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.25%. The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 230 · version 2026-1 · source checked 2026-08-30

3-Nitro-4-aminophenoxyethanol and its salts, when used as a

CAS 50982-74-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1250 · version 2026-1 · source checked 2026-08-30

3-Oxoandrost-4-ene-17-ß-carboxylic acid

CAS 302-97-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1488 · version 2026-1 · source checked 2026-08-30

3-Pyridinemethanol hydrofluoride Nicomethanol Hydrofluoride CAS No 62756-44-9

CAS 62756-44-9 · EC 700-352-1 (L)

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Oral hygiene products (except mouthwash) (b) Mouthwash · 0.15% calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15% · (a) & (b) Contains nicomethanol hydrofluoride (a) "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimise swallowing. In case of intake of fluoride from other sources consult a dentist or doctor." (12) (b) only Do not use for children below 6 years of age

Source:ASEAN Annex III, reference 47 · version 2026-1 · source checked 2026-08-30

3-[(2-nitro-4-(trifluoromethyl)phenyl)amino]propane-1,2-diol (HC

CAS 104333-00-8 · EC 410-010-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1324 · version 2026-1 · source checked 2026-08-30

3-[(4-(Acetylamino)phenyl)azo]-4-hydroxy-7-[[[[5-hydroxy-6-

CAS 3441-14-3 · EC 222-348-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1269 · version 2026-1 · source checked 2026-08-30

3-[(4-amino-3- methyl-9,10-dioxo-9,10- dihydroanthracen-1- yl)amino]-N,N,N - trimethylpropan-1-aminium, methylsulfate salt HC Blue No 17 CAS No 16517-75-2

CAS 16517-75-2

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 2.0 % · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 % For (a) and (b): —Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg(21) — Keep in nitrite-free containers The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a)To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past. (a) and (b) Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 303 · version 2026-1 · source checked 2026-08-30

3-[[4-[(2-Hydroxyethyl)Methylamino]-2-Nitrophenyl]amino]-1,2-

CAS 173994-75-7; 102767-27-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1326 · version 2026-1 · source checked 2026-08-30

3-[[4-[(2-Hydroxyethyl)amino]-2-nitrophenyl]amino]-1,2-

CAS 114087-41-1; 114087-42-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1327 · version 2026-1 · source checked 2026-08-30

3-amino-2-chlor- 6-methylphenol 3-amino-4-chloro-6-methylphenol HCl 5-Amino-6-Chloro-O-Cresol CAS No. 84540-50-1 5-Amino-6-Chloro-O-Cresol HCl CAS No. 80419-48-3

CAS 84540-50-1; 80419-48-3 · EC 283-144-9

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 0.5 % · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 % (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a) To be printed on the label: The mixing ratio. “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. (a) and (b) Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 283 · version 2026-1 · source checked 2026-08-30

3-methylpyrazole

CAS 453-58-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1686 · version 2026-1 · source checked 2026-08-30

3H-Indolium, 2-(2-((2,4-dimethoxyphenyl)amino)ethenyl)-1,3,3-

CAS 4208-80-4 · EC 224-132-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1273 · version 2026-1 · source checked 2026-08-30

3H-Indolium, 2-[[(4-methoxyphenyl)methylhydrazono]methyl]-

CAS 54060-92-3 · EC 258-946-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1272 · version 2026-1 · source checked 2026-08-30

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-

CAS 596-03-2; 4372-02-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1333 · version 2026-1 · source checked 2026-08-30

4'-Ethoxy-2-benzimidazoleanilide

CAS 120187-29-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1005 · version 2026-1 · source checked 2026-08-30

4,4'- Isobutylethylidenediphenol

CAS 6807-17-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1079 · version 2026-1 · source checked 2026-08-30

4,4'-(1,3-Phenylene-bis(1-methylethylidene))bis-phenol

CAS 13595-25-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1476 · version 2026-1 · source checked 2026-08-30

4,4'-(4-Iminocyclohexa-2,5-dienylidenemethylene) dianiline

CAS 69-61-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 706 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine

CAS 119-93-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 721 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine dihydrochloride

CAS 612-82-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 722 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine sulphate

CAS 74753-18-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 724 · version 2026-1 · source checked 2026-08-30

4,4'-Bis(N-carbamoyl-4-

CAS 151882-81-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1467 · version 2026-1 · source checked 2026-08-30

4,4'-Bis(dimethylamino)benzophenone; (Michler's ketone)

CAS 90-94-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1149 · version 2026-1 · source checked 2026-08-30

4,4'-Carbonimidoylbis[N,N-dimethylaniline] and its salts

CAS 492-80-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1067 · version 2026-1 · source checked 2026-08-30

4,4'-Diaminodiphenylamine and its salts, when used as a

CAS 537-65-5 · EC 208-673-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1309 · version 2026-1 · source checked 2026-08-30

4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 207 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenebis(2-ethylaniline)

CAS 19900-65-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1038 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenedi-o-toluidine

CAS 838-88-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 707 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenedianiline

CAS 101-77-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 705 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'- diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p- Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'- diisocyanate [3]; Methylenediphenyl diisocyanate [4]

4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'- diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p- Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'- diisocyanate [3]; Methylenediphenyl di

CAS 101-68-8 · EC 202-966-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1533 · version 2026-1 · source checked 2026-08-30

4,4'-Oxydianiline (p-aminophenyl ether) and its salts

CAS 101-80-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1160 · version 2026-1 · source checked 2026-08-30

4,4'-Thiodianiline and its salts

CAS 139-65-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1159 · version 2026-1 · source checked 2026-08-30

4,4'-[(4-Methyl-1,3-phenylene)bis(azo)]bis[6-methyl-1,3-

CAS 4482-25-1 · EC 224-764-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1296 · version 2026-1 · source checked 2026-08-30

4,4-Dimethyl-1,3-oxazolidine CAS No. 51200-87-4

CAS 51200-87-4 · EC 257-048-2

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.1% · The pH of the finished product must not be lower than 6

Source:ASEAN Annex VI, reference 45 · version 2026-1 · source checked 2026-08-30

4,4’-sulphonyldiphenol; bisphenol S

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1702 · version 2026-1 · source checked 2026-08-30

4,4′-[1,3- Propanediylbis(oxy)]bisbenzene-1,3- diamine and its tetrahydrochloride salt 1,3-bis-(2,4-Diaminophenoxy) propane CAS No. 81892-72-0 1,3-bis-(2,4-Diaminophenoxy) propane HCl CAS No. 74918-21-1

CAS 81892-72-0; 74918-21-1 · EC 279-845-4

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 1.2% as free base (1.8% as tetrahydro chloride salt) · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt). The free base and salts of this hair colouring ingredient, unless prohibited under Annex II, are permitted for use. The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past. Do not use to dye eyelashes or eyebrows (b) Can cause allergic reaction Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 202 · version 2026-1 · source checked 2026-08-30

4,5-Diamino-1-((4-chlorophenyl)methyl)-1H-pyrazole sulfate,

CAS 163183-00-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1218 · version 2026-1 · source checked 2026-08-30

4,5-Diamino-1-(2- hydroxyethyl)-1H- pyrazole sulfate (1:1) 1-Hydroxyethyl-4,5- Diamino Pyrazole Sulfate CAS No 155601-30-2

CAS 155601-30-2 · EC 429-300-3

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.0 % The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows”

Source:ASEAN Annex III, reference 297 · version 2026-1 · source checked 2026-08-30

4,5-Diamino-1-methylpyrazole and its HCl salt, when used as a

CAS 20055-01-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1217 · version 2026-1 · source checked 2026-08-30

4,6-Bis(2-hydroxyethoxy)-m-phenylenediamine and its salts,

CAS 94082-85-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1307 · version 2026-1 · source checked 2026-08-30

4,6-Dimethyl-8-tert-butylcoumarin, when used as a fragrance

CAS 17874-34-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 430 · version 2026-1 · source checked 2026-08-30

4-((4-Amino-3- methylphenyl)(4- imino- 3-methyl- 2,5-cyclohexadien-1- ylidene)methyl)-2- methylphenylamine monohydrochloride (CI 42520) Basic Violet 2 CAS No 3248-91-7

CAS 3248-91-7

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 0.5 % · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 % (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. (a) and (b) Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 302 · version 2026-1 · source checked 2026-08-30

4-(2,4-Dihydroxyphenylazo)benzenesulphonic acid and its

CAS 2050-34-2; 547-57-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1330 · version 2026-1 · source checked 2026-08-30

4-(3-aminopyrazolo[1,5-A] pyridin-2- yl)-1,1-dimethylpiperazin-1-ium chloride hydrochloride Dimethylpiperazinium Aminopyrazolopyridine HCl 1256553- 33-9

CAS 1256553-33-9 · EC 813-255-5

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % (calculated as free base) · To be printed on the label: The mixing ratio. ‘ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’

Source:ASEAN Annex III, reference 330 · version 2026-1 · source checked 2026-08-30