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InventoryRef 9192028/07/2020

HYDROXYETHOXYPHENYL BUTANONE

4-(3-ethoxy-4-hydroxyphenyl)butan-2-one

HYDROXYETHOXYPHENYL BUTANONE is linked to 1 EU annex record on this page.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Positive-list entry with conditions
Open this evidence
1English and EU languages
Great BritainEvidence linked
Permitted list with conditions
Open this evidence
1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence
1English
ASEANEvidence linked
Permitted list with conditions
Open this evidence
1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 569646-79-3
CAS 569646-79-3PubChem CID 45094126

4-(3-Ethoxy-4-hydroxyphenyl)-2-butanone

Ethylzingerone is a methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by ethoxy and hydroxy groups, respectively. It is a preservative with antimicrobial activity and a good safety profile that has been approved for use in cosmetics. It is structurally similar to zingerone, a phytochemical found in the root of the ginger plant Zingiber officinale. It has a role as an antimicrobial cosmetic preservative, an antibacterial agent and an antifungal agent. It is a member of phenols, an aromatic ether and a methyl ketone. ChEBI

IUPAC name
4-(3-ethoxy-4-hydroxyphenyl)butan-2-one
Molecular formula
C12H16O3
Molecular weight
208.25 g/mol
Exact mass
208.109944368 Da
XLogP3
1.2
Topological polar surface area
46.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

ethylzingeroneUNII-TH7XI54W45TH7XI54W452-Butanone, 4-(3-ethoxy-4-hydroxyphenyl)-CHEBI:172922RefChem:97147HYDROXYETHOXYPHENYL BUTANONE2-Butanone,4-(3-ethoxy-4-hydroxyphenyl)-(7CI)
4 more reported names
Hydroxyethoxyphenyl butanone [INCI]4-(3-ethoxy-4-hydroxy-phenyl)butan-2-oneCS-0256997EN300-65784
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for HYDROXYETHOXYPHENYL BUTANONE

INCI name

HYDROXYETHOXYPHENYL BUTANONE

Description

4-(3-ethoxy-4-hydroxyphenyl)butan-2-one

Record provenance

Inventory reference
91920
Imported identity
HYDROXYETHOXYPHENYL BUTANONE
Source update
28/07/2020
European Commission CosIng source notes

Key data

Restriction
Function
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How HYDROXYETHOXYPHENYL BUTANONE appears in the CosIng inventory

The CosIng inventory lists HYDROXYETHOXYPHENYL BUTANONE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HYDROXYETHOXYPHENYL BUTANONE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HYDROXYETHOXYPHENYL BUTANONE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, HYDROXYETHOXYPHENYL BUTANONE carries the following function designation(s):

CAS 569646-79-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for HYDROXYETHOXYPHENYL BUTANONE

This page combines the CosIng inventory entry for HYDROXYETHOXYPHENYL BUTANONE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HYDROXYETHOXYPHENYL BUTANONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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