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InventoryRef 3266610/08/2020

CHLOROXYLENOL

Phenol, 4-chloro-3,5-dimethyl-

CHLOROXYLENOL is linked to 1 EU annex record on this page. Inventory note: V/26.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Positive-list entry with conditions
Open this evidence		1English and EU languages
Great BritainEvidence linked
Permitted list with conditions
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence		1English
ASEANEvidence linked
Permitted list with conditions
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Restricted
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 1321-23-9
CAS 1321-23-9PubChem CID 74075

Phenol, chlorodimethyl-

IUPAC name
4-chloro-2,3-dimethylphenol
Molecular formula
C8H9ClO
Molecular weight
156.61 g/mol
Exact mass
156.0341926 Da
XLogP3
2.2
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

RefChem:8613211570-76-94-Chloro-2,3-xylenolChlorodimethylhydroxybenzenePhenol, 4-chloro-2,3-dimethyl-2,3-Xylenol, 4-chloro-NSC-60150Xylenol, chloro-
11 more reported names
2,3-dimethyl-4-chlorophenol4-chloro-2,3-dimethyl-phenolEINECS 215-316-6NSC 601503-methyl-4-chlorocresol4-chloro-3-methylcresolCFS3B2E4N4WZG0278DB-153722CS-0191115InChI=1/C8H9ClO/c1-5-6(2)8(10)4-3-7(5)9/h3-4,10H,1-2H
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 88-04-0
CAS 88-04-0PubChem CID 2723

4-Chloro-3,5-dimethylphenol

4-chloro-3,5-dimethylphenol is a member of the class of phenols that is 3,5-xylenol which is substituted at position 4 by chlorine. It is bactericidal against most Gram-positive bacteria but less effective against Staphylococci and Gram-negative bacteria, and often inactive against Pseudomonas species. It is ineffective against bacterial spores. It has a role as a molluscicide, an antiseptic drug and a disinfectant. It is a member of phenols and a member of monochlorobenzenes. It is functionally related to a 3,5-xylenol. — ChEBI

IUPAC name
4-chloro-3,5-dimethylphenol
Molecular formula
C8H9ClO
Molecular weight
156.61 g/mol
Exact mass
156.0341926 Da
XLogP3
2.0
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

chloroxylenolPCMX4-Chloro-3,5-xylenolBenzytolp-Chloro-m-xylenolOttaseptparachlorometaxylenol2-Chloro-m-xylenol
16 more reported names
4-Chloro-m-xylenolDessonEspadolChloro-xylenolOttasept ExtraPhenol, 4-chloro-3,5-dimethyl-Husept ExtraWillenol V3,5-Dimethyl-4-chlorophenolp-Chloro-3,5-xylenolCloroxilenolSeptiderm-HydrochlorideChloroxylenolumChlorxylenolumDettol, liquid antiseptic2-Chloro-5-hydroxy-m-xylene
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CHLOROXYLENOL

INCI name

CHLOROXYLENOL

INN name

chloroxylenol

Description

Phenol, 4-chloro-3,5-dimethyl-

Record provenance

Inventory reference
32666
Imported identity
CHLOROXYLENOL
Source update
10/08/2020
European Commission CosIng source notes
Annex V Restriction reference
Entry 26

CHLOROXYLENOL

CAS: 88-04-0 / 1321-23-9
EC: 201-793-8 / 215-316-6

Key data

CAS
88-04-0 / 1321-23-9
EC
201-793-8 / 215-316-6
Restriction
V/26
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
DEODORANT
Reducing and/or eliminating unpleasant odour. Contributing against the formation of malodour on body surfaces.
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6237 · CHLOROXYLENOL

The 5 markets that hold a rule for this substance do not classify it the same way.

restricted
South Korea
permitted on a positive list
European UnionGreat BritainNew ZealandASEAN

See every substance the markets disagree about

Ingredients with overlapping formulation functions

CHLORINE DIOXIDEANTIMICROBIAL, DEODORANT
CHLOROPHYLLIN-COPPER COMPLEXANTIOXIDANT, COLORANT, DEODORANT
CHLOROTHYMOLANTIMICROBIAL, ANTIPLAQUE, DENATURANT, DEODORANT, ORAL CARE
CHLOROUS ACIDANTICORROSIVE; ANTIMICROBIAL; DEODORANT; ORAL CARE; OXIDISING
CITRUS LATIFOLIA FRUIT JUICEANTIOXIDANT, DEODORANT, FLAVOURING, SURFACTANT - CLEANSING
CITRUS RETICULATA PEEL OILDEODORANT, FLAVOURING, FRAGRANCE, PERFUMING
CLOFLUCARBANANTIMICROBIAL, DEODORANT
COIX LACRYMA-JOBI MA-YUEN SEED/PUERARIA LOBATA ROOT/GANODERMA LUCIDUM EXTRACTASTRINGENT, DEODORANT, FLAVOURING, HUMECTANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How CHLOROXYLENOL appears in the CosIng inventory

The CosIng inventory lists CHLOROXYLENOL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CHLOROXYLENOL is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CHLOROXYLENOL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CHLOROXYLENOL reads: "V/26". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CHLOROXYLENOL carries the following function designation(s):

CAS 88-04-0 / 1321-23-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CHLOROXYLENOL

This page combines the CosIng inventory entry for CHLOROXYLENOL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CHLOROXYLENOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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