TOLUENE DIISOCYANATE
m-tolylidene diisocyanate [1]; 4-methyl-m-phenylene diisocyanate [2]; 2-methyl-m-phenylene diisocyanate [3]
TOLUENE DIISOCYANATE is linked to 3 EU annex records on this page. Inventory note: CMR2 II/1118, II/1119, II/1120.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
Swipe or scroll horizontally to see every column.
| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 3 | English and EU languages |
| Great Britain | Evidence linked Prohibited Open this evidence | 3 | English |
| Canada | Evidence linked Prohibited Open this evidence | 1 | English and French |
| New Zealand | Evidence linked Prohibited Open this evidence | 3 | English |
| ASEAN | Evidence linked Prohibited Open this evidence | 3 | English and national languages |
| China | Evidence linked Prohibited Open this evidence | 3 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Evidence linked Prohibited Open this evidence | 3 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Evidence linked Prohibited Open this evidence | 3 | Portuguese with INCI crosswalks |
| India | Evidence linked Prohibited Open this evidence | 3 | English and Hindi |
| Saudi Arabia | Evidence linked Prohibited Open this evidence | 3 | Arabic and English |
Chemical identity and properties
Toluene 2,4-Diisocyanate
Toluene 2,4-diisocyanate is a toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring. It has a role as an allergen and a hapten. — ChEBI
- IUPAC name
- 2,4-diisocyanato-1-methylbenzene
- Molecular formula
- C9H6N2O2
- Molecular weight
- 174.16 g/mol
- Exact mass
- 174.042927438 Da
- XLogP3
- 3.9
- Topological polar surface area
- 58.9 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:53556
- ChEMBL:CHEMBL1086446
- EPA DTXSID:DTXSID7026156
- PubMed:41678259
- PubMed:38616237
- PubMed:33711354
- PubMed:33075463
- PubMed:31577921
- PubMed:31071364
- PubMed:31070765
- PubMed:30517707
- PubMed:30445053
- PubMed:30261222
- PubMed:30017638
- PubMed:29940203
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Toluene 2,6-Diisocyanate
Toluene 2,6-diisocyanate is a toluene meta-diisocyanate in which the isocyanato groups are at positions 2 and 6 relative to the methyl group on the benzene ring. It has a role as an allergen and a hapten. — ChEBI
- IUPAC name
- 1,3-diisocyanato-2-methylbenzene
- Molecular formula
- C9H6N2O2
- Molecular weight
- 174.16 g/mol
- Exact mass
- 174.042927438 Da
- XLogP3
- 3.9
- Topological polar surface area
- 58.9 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:53557
- ChEMBL:CHEMBL1443390
- EPA DTXSID:DTXSID2026157
- PubMed:22952646
- PubMed:21458408
- PubMed:21447151
- PubMed:20957106
- PubMed:20933064
- PubMed:20466021
- PubMed:20085231
- PubMed:20032816
- PubMed:18291409
- PubMed:18280204
- PubMed:17431479
- PubMed:16434466
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for TOLUENE DIISOCYANATE
INCI name
TOLUENE DIISOCYANATE
Description
m-tolylidene diisocyanate [1]; 4-methyl-m-phenylene diisocyanate [2]; 2-methyl-m-phenylene diisocyanate [3]
Record provenance
- Inventory reference
- 95283
- Imported identity
- TOLUENE DIISOCYANATE
- Source update
- 19/09/2018
Annex records for TOLUENE DIISOCYANATE
2-Methyl-m-phenylene diisocyanate (Toluene 2,6-diisocyanate)
4-Methyl-m-phenylene diisocyanate (Toluene 2,4-diisocyanate)
m-Tolylidene diisocyanate (Toluene diisocyanate)
Key data
- NOT REPORTED
- No function currently reported.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How TOLUENE DIISOCYANATE appears in the CosIng inventory
The CosIng inventory lists TOLUENE DIISOCYANATE as a cosmetic ingredient and this page links it to 3 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
TOLUENE DIISOCYANATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for TOLUENE DIISOCYANATE
This page combines the CosIng inventory entry for TOLUENE DIISOCYANATE with 3 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research TOLUENE DIISOCYANATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
Check your formula
Scan a full INCI list to detect TOLUENE DIISOCYANATE and any linked EU annex restrictions or allergen flags.
INCI CheckerSearch similar ingredients
Find other inventory ingredients and annex entries related to TOLUENE DIISOCYANATE, its identifiers or nearby name variants.
Search