Canada cosmetic ingredient regulations

1-Naphthol, and its salts

Canada Hotlist: 1-Naphthol, and its salts

CAS 90-15-3 · EC 201-969-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) In Hair dyes as an oxidizing colouring agent | b) In combination with hydrogen peroxide · Maximum concentration: a) 2% | b) 1%

Source:Hotlist restricted entry 1 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Bromo-2-nitropropane-1,3-diol

Canada Hotlist: 2-Bromo-2-nitropropane-1,3-diol

CAS 52-51-7 · EC 200-143-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics that contain amines or amides. | b) Other cosmetics · Maximum concentration: b) 0.1%

Source:Hotlist restricted entry 2 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5-Bromo-5-nitro-1,3-dioxane

Canada Hotlist: 5-Bromo-5-nitro-1,3-dioxane

CAS 30007-47-7 · EC 250-001-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics that contain amines or amides. | b) Other cosmetics · Maximum concentration: b) 0.1%

Source:Hotlist restricted entry 3 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

7,11-Dimethyl-4,6,10-dodecatrien-3-one

Canada Hotlist: 7,11-Dimethyl-4,6,10-dodecatrien-3-one

CAS 26651-96-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 2% as an impurity in methylionones

Source:Hotlist restricted entry 4 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

8-Hydroxyquinoline and its sulfate

Canada Hotlist: 8-Hydroxyquinoline and its sulfate

CAS 148-24-3; 134-31-6

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: 8-Hydroxyquinoline sulfate; Oxyquinoline; Oxyquinoline Sulfate | a) As stabilizers for hydrogen peroxide in rinse-off hair products | b) As stabilizers for hydrogen peroxide in leave-on hair products · Maximum concentration: a) 0.3% | b) 0.03%

Source:Hotlist restricted entry 5 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Alkali earth metal sulfides

Canada Hotlist: Alkali earth metal sulfides

CAS 21109-95-5; 20548-54-3; 12032-36-9; 1314-96-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Barium sulfide; Calcium sulfide; Magnesium sulfide; Strontium sulfide | In hair removal (depilatory) products · Maximum concentration: 6% as sulfur

Source:Hotlist restricted entry 6 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Alkali sulfides

Canada Hotlist: Alkali sulfides

CAS 12136-58-2; 1312-73-8; 1313-82-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Lithium sulfide; Potassium sulfide; Sodium sulfide | In hair removal (depilatory) products · Maximum concentration: 2% as sulfur

Source:Hotlist restricted entry 7 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts

Canada Hotlist: Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts

CAS 77-92-9; 79-14-1; 50-21-5; 133-37-9; 6915-15-7; 79-33-4; 5949-29-1; 617-73-2; 90-64-2; 35249-89-9

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Citric acid; Glycolic acid; Lactic acid; Malic acid; Mandelic acid; Tartaric acid; Ammonium glycolate; Sodium citrate; Hydroxycaprylic acid; Mixed fruit acids; Gluconolactone; Ammonium gluconate; Lactobionic acid; Calcium lactobionate | a) Products for use on the skin for consumer use Manufacturer or importer to provide pH levels | b) Products for use on the skin for professional use Manufacturer or importer to provide evidence of safety, including: pH levels AHA concentrations directions for use clinical studies demonstrating minimal skin irritation | c) Products intended to be diluted in bath water may contain levels of AHAs exceeding 10% | d) Other cosmetics | e) Any cosmetics · Maximum concentration: a) Between 3% and 18% total mono-AHA equivalents with a pH equal to or greater than 3.5 | b) Between 18% and 30% total mono-AHA equivalents and/or a pH between 3.0 to 3.5 | d) Between 3% and 30% total mono-AHA equivalents with a pH equal to or greater than 3.0 | 3% · Warnings: a) and b) "Use only as directed" "Avoid contact with the eyes" "If irritation persists, discontinue use and consult a physician" "It is recommended that prior to exposure to the sun, users cover areas where AHAs have been applied with sunscreen" Product labels should contain appropriate directions regarding frequency and/or duration of use b only) "For professional use only" | d) "Use only as directed" "Avoid contact with eyes" "Discontinue use if rash or irritation occurs"

Source:Hotlist restricted entry 8 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Aluminum chloride

Canada Hotlist: Aluminum chloride

CAS 7446-70-0; 7784-13-6 · EC 231-208-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Deodorants and antiperspirants containing aluminum chloride are not permitted in aerosol dispensers. | b) Not permitted in combination with aluminum chlorohydrate or its associated complexes or aluminum zirconium complexes | c) Deodorants and antiperspirants containing aluminum chloride must be in the form of an aqueous solution. · Maximum concentration: c) 15% calculated as aluminum chloride hexahydrate · Warnings: c) "Discontinue use if rash or irritation occurs." "Do not use on broken skin."

Source:Hotlist restricted entry 9 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Aluminum chlorohydrate and its associated complexes

Canada Hotlist: Aluminum chlorohydrate and its associated complexes

CAS 12042-91-0; 1327-41-9; 173762-81-7; 173762-82-8; 10284-64-7; 173720-80-4; 180324-83-8; 11097-68-0; 173763-15-0; 242812-86-8; 173763-16-1; 245090-60-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Aluminum chlorohydrate; Aluminum chlorohydrex PEG; Aluminum chlorohydrex PG; Aluminum dichlorohydrate; Aluminum dichlorohydrex PEG; Aluminum dichlorohydrex PG; Aluminum sesquichlorohydrate; Aluminum sesquichlorohydrex PEG; Aluminum sesquichlorohydrex PG | a) Not permitted in combination with aluminum chloride, other aluminum chlorohydrate complexes or aluminum zirconium complexes. | b) Deodorants and antiperspirants | c) Deodorants and antiperspirants in aerosol dispensers · Maximum concentration: b,c) 25% (calculated as the anhydrous form). | c) "Discontinue use if rash or irritation occurs." "Do not use on broken skin." "Keep away from face to avoid inhalation and spraying in the eyes." "Keep out of reach of children." · Warnings: b) "Discontinue use if rash or irritation occurs." "Do not use on broken skin."

Source:Hotlist restricted entry 10 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Aluminum zirconium complexes

Canada Hotlist: Aluminum zirconium complexes

CAS 98106-55-9; 174514-58-0; 173762-83-9; 98106-54-8; 125913-22-6; 57158-29-9; 98106-52-6; 90604-80-1; 134910-86-4; 246867-10-7; 235433-35-9; 98106-53-7; 134375-99-8

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Aluminum zirconium octachlorohydrate; Aluminum zirconium octachlorohydrex GLY; Aluminum zirconium pentachlorohydrate; Aluminum zirconium pentachlorohydrex GLY; Aluminum zirconium tetrachlorohydrate; Aluminum zirconium tetrachlorohydrex GLY; Aluminum zirconium tetrachlorohydrex PEG; Aluminum zirconium tetrachlorohydrex PG; Aluminum zirconium trichlorohydrate; Aluminum zirconium trichlorohydrex GLY | a) Not permitted in deodorants and antiperspirants in aerosol dispensers. | b) Not permitted in combination with aluminum chloride, aluminum chlorohydrate or its associated complexes or other aluminum zirconium complexes. | c) Other cosmetics · Maximum concentration: c) 20% (calculated as the anhydrous form) · Warnings: c) "Discontinue use if rash or irritation occurs." "Do not use on broken skin."

Source:Hotlist restricted entry 11 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Azelaic acid and its salts

Canada Hotlist: Azelaic acid and its salts

CAS 123-99-9; 52457-54-2; 132499-85-5; 17265-13-3; 27825-99-6

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Nonanedioic acid; Disodium Azelate; Dipotassium Azelate · Maximum concentration: 14%

Source:Hotlist restricted entry 12 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Barium salts

Canada Hotlist: Barium salts

CAS 21109-95-5; 7727-43-7 · EC 244-214-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Permitted only as barium sulfide in hair removal products (see " Alkali earth metal sulfides "), as barium sulfate, or as a colouring agent or lake for preparation of other colouring agents.

Source:Hotlist restricted entry 13 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Benzalkonium chloride

Canada Hotlist: Benzalkonium chloride

CAS 8001-54-5; 61789-71-7; 68391-01-5; 68424-85-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Alkyl(C12-C18)benzyldimethylammonium chloride; Alkyl(C12-16)dimethylbenzylammonium chloride | a) As a preservative (i.e. benzalkonium chloride with chain lengths ≤ 14 C). | b) As a conditioning agent in rinse-off hair care products, (i.e. benzalkonium chloride with chain lengths ≥ 16 C). · Maximum concentration: a) 0.1% | b) 3% · Warnings: b) All products containing more than 0.1%: "Avoid contact with eyes."

Source:Hotlist restricted entry 14 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Benzethonium chloride

Canada Hotlist: Benzethonium chloride

CAS 121-54-0 · EC 204-479-9

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in products to be applied to mucous membranes. | b) Leave-on products | c) Rinse-off products · Maximum concentration: b) 0.2% | c) 0.3%

Source:Hotlist restricted entry 15 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Benzophenone

Canada Hotlist: Benzophenone

CAS 119-61-9 · EC 204-337-6

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 3%

Source:Hotlist restricted entry 16 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Benzoyl peroxide

Canada Hotlist: Benzoyl peroxide

CAS 94-36-0 · EC 202-327-6

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Permitted only in nail products for professional use · Maximum concentration: 10% · Warnings: "For professional use only" "Avoid skin contact" "Read directions carefully before using"

Source:Hotlist restricted entry 17 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Boric acid and its salts

Canada Hotlist: Boric acid and its salts

CAS 10043-35-3; 11113-50-1; 10377-81-8; 68130-12-1; 26038-90-4; 68003-13-4; 10192-46-8; 1332-07-6; 22694-75-3; 27522-09-4; 13703-82-7; 12007-62-4; 1333-73-9; 13840-56-7; 7775-19-1; 1330-43-4; 1303-96-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: MEA borate; MIPA borate; Potassium borate; Zinc Borate; Ammonium borate; Magnesium borate; Borax; Sodium borate; Sodium tetraborate; Sodium tetraborate decahydrate | a) As a pH adjuster | b) Other cosmetics · Maximum concentration: a) 0.1% | b) 5% · Warnings: b) "Do not use on broken or abraded skin, not to be used by children under three years of age."

Source:Hotlist restricted entry 18 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Brucine

Canada Hotlist: Brucine

CAS 357-57-3

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 0.1%

Source:Hotlist restricted entry 19 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Butane

Canada Hotlist: Butane

CAS 106-97-8 · EC 203-448-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 0.1% w/w of 1,3-butadiene (106-99-0)

Source:Hotlist restricted entry 20 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Butoxyethanol

Canada Hotlist: Butoxyethanol

CAS 111-76-2 · EC 203-905-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Permitted in hair dyes and nail products only. · Maximum concentration: 10%

Source:Hotlist restricted entry 21 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Calcium peroxide

Canada Hotlist: Calcium peroxide

CAS 1305-79-9 · EC 215-139-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Calcium dioxide | See " Peroxide and peroxide-generating compounds ".

Source:Hotlist restricted entry 22 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Camphor

Canada Hotlist: Camphor

CAS 76-22-2 · EC 207-355-2 / 200-945-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 3%

Source:Hotlist restricted entry 23 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Cannabis spp. derivatives or a product made from those derivatives that are exempt from the application of the Cannabis Act

Canada Hotlist: Cannabis spp. derivatives or a product made from those derivatives that are exempt from the application of the Cannabis Act

CAS 8016-24-8; 89958-21-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Cannabis sativa seed oil; Hemp seed oil; Hydrolyzed Hemp seed protein | Cosmetics must not contain an isolated or concentrated phytocannabinoid or a synthetic duplicate of that phytocannabinoid

Source:Hotlist restricted entry 24 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Catalase

Canada Hotlist: Catalase

CAS 9001-05-2 · EC 232-577-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Warnings: "This product is not intended for use on broken or abraded skin."

Source:Hotlist restricted entry 25 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Chlorhexidine and its salts

Canada Hotlist: Chlorhexidine and its salts

CAS 55-56-1; 56-95-1; 18472-51-0; 3697-42-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: b) 0.19% calculated as chlorhexidine diacetate | c) 0.20% calculated as chlorhexidine digluconate | d) 0.16% calculated as chlorhexidine dihydrochloride · Maximum concentration: a) 0.14% calculated as chlorhexidine free base

Source:Hotlist restricted entry 26 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Cholecalciferol

Canada Hotlist: Cholecalciferol

CAS 67-97-0 · EC 200-673-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Vitamin D3 | Average daily absorption must be equal to or less than 25 µg per day.

Source:Hotlist restricted entry 27 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Citric acid

Canada Hotlist: Citric acid

CAS 77-92-9 · EC 201-069-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Alpha-hydroxy acids ".

Source:Hotlist restricted entry 28 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Citrus reticulata leaf oil

Canada Hotlist: Citrus reticulata leaf oil

CAS 8014-17-3 · EC - / 284-521-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Leave-on products | b) Rinse off products · Maximum concentration: 0.1%

Source:Hotlist restricted entry 29 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Coal tar dye

Canada Hotlist: Coal tar dye

CAS 95-70-5; 615-50-9

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Toluene-2,5-diamine; Toluene-2,5-diamine sulfate; See also “ p -Phenylenediamine and its salts ” | a) Not permitted in the area of the eye as indicated in section 14 of the Cosmetic Regulations. | b) In hair dyes as indicated in section 22 of the Cosmetic Regulations. · Warnings: On the inner label and the outer label of the cosmetic: "CAUTION: this product contains ingredients that may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dying the eyelashes or eyebrows. To do so may cause blindness." Instructions to the following effect accompany each package of hair dye: The preparation may cause serious inflammation of the skin in some persons, and a preliminary test should always be carried out to determine whether or not special sensitivity exists; and To make the test, a small area of skin behind the ear or on the inner surface of the forearm should be cleansed, using either soap and water or alcohol, and a small quantity of the hair dye, as prepared for use, should be applied to the area and allowed to dry. After 24 hours, the area should be washed gently with soap and water. If no irritation or inflammation is apparent, it is usually assumed that no hypersensitivity to the dye exists. The test should, however, be carried out before each application. On no account should the hair dye be used for dyeing eyebrows or eyelashes as severe inflammation of the eye or even blindness may result."

Source:Hotlist restricted entry 30 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Cyanoacrylate-based adhesives

Canada Hotlist: Cyanoacrylate-based adhesives

CAS 7085-85-0; 137-05-3; 10586-17-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Ethyl cyanoacrylate; Methyl cyanoacrylate; Isopropyl cyanoacrylate | a) Cyanoacrylate adhesives for eyelash extensions must be sold for professional use only (i.e., not for direct sale to consumers). | b) Other cosmetics · Maximum concentration: b) "WARNING. BONDS SKIN INSTANTLY. AVOID CONTACT WITH EYES, MOUTH AND SKIN. KEEP AWAY FROM CHILDREN. Eyelid bonding: consult a physician. Skin bonding: soak and ease apart gently. Not for use in the area of the eye." · Warnings: a) "For application by trained professionals only" and "Ensure the eye is protected and immobilized during application." "WARNING. BONDS SKIN INSTANTLY. AVOID CONTACT WITH EYES, MOUTH AND SKIN. KEEP AWAY FROM CHILDREN. Eyelid bonding: consult a physician. Skin bonding: soak and ease apart gently."

Source:Hotlist restricted entry 31 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Diethylene glycol

Canada Hotlist: Diethylene glycol

CAS 111-46-6 · EC 203-872-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: DEG | Not permitted in oral or leave-on products (see also " Glycerin ").

Source:Hotlist restricted entry 32 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Diethylhexyl Adipate

Canada Hotlist: Diethylhexyl Adipate

CAS 103-23-1 · EC 203-090-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: DEHA; Dioctyl Adipate; Bis(2-Ethylhexyl)Hexanedioate | a) Leave-on body moisturizers | b) Other cosmetics · Maximum concentration: a) 6.0%

Source:Hotlist restricted entry 33 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Dihydrocoumarin

Canada Hotlist: Dihydrocoumarin

CAS 119-84-6 · EC 204-354-9

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Leave-on products | b) Rinse-off products · Maximum concentration: 0.035% | 3.5%

Source:Hotlist restricted entry 34 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Ergocalciferol

Canada Hotlist: Ergocalciferol

CAS 50-14-6 · EC 200-014-9 / 215-797-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Vitamin D2 | Average daily absorption should be equal to or less than 25 µg per day.

Source:Hotlist restricted entry 35 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Ethyl methacrylate

Canada Hotlist: Ethyl methacrylate

CAS 97-63-2 · EC 202-597-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Warnings: "Avoid skin contact."

Source:Hotlist restricted entry 37 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Ethylhexyl Ethylhexanoate

Canada Hotlist: Ethylhexyl Ethylhexanoate

CAS 7425-14-1 · EC 231-057-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: 2-Ethylhexyl-2-ethylhexanoate | a) Body lotion | b) Foot lotion | c) Face make-up · Maximum concentration: 0.1% | 0.5% | 0.6%

Source:Hotlist restricted entry 36 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Eucalyptus oil

Canada Hotlist: Eucalyptus oil

CAS 8000-48-4; 85203-56-1; 1627700-32-6; 91771-69-6; 90028-48-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Eucalyptus Globulus Leaf Oil; Eucalyptus Citriodora Oil; Eucalyptus Radiata Leaf/Stem Oil; Eucalyptus Staigeriana Branch/Leaf Oil; Eucalyptus Dives Leaf/Twig Oil | a) Cosmetics in solid forms | b) Cosmetics in other forms with greater than 0.022% | c) Cosmetics in other forms with less than or equal to 0.022% · Warnings: b) "Keep out of reach of children", and "In case of accidental ingestion, call a Poison Control Centre or doctor immediately and advise them this product contains eucalyptus oil."

Source:Hotlist restricted entry 38 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Fluoride containing substances

Canada Hotlist: Fluoride containing substances

CAS 16984-48-8; 1333-83-1; 7681-49-4; 7789-75-5; 7783-47-3; 10163-15-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Sodium fluoride; Calcium fluoride; Stannous fluoride; Sodium monofluorophosphate | a) Not permitted in oral products. | b) other products

Source:Hotlist restricted entry 39 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Formaldehyde

Canada Hotlist: Formaldehyde

CAS 50-00-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in aerosol products. | b) Non-aerosol products that release formaldehyde vapours when used according to directions. | c) Oral products | d) Non-oral products as a preservative | e) Nail hardeners, must be sold with nail shields and directions for use. · Maximum concentration: b) 0.01% | c) 0.1% | d) 0.2% | e) 5.0% · Warnings: e) "This product contains formaldehyde which has the potential to cause skin sensitivity."

Source:Hotlist restricted entry 40 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Furocoumarins, except for naturally occurring in plant extracts

Canada Hotlist: Furocoumarins, except for naturally occurring in plant extracts

CAS 66-97-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Sun tanning products · Maximum concentration: 1 mg/kg (1 ppm)

Source:Hotlist restricted entry 41 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Glycerin

Canada Hotlist: Glycerin

CAS 56-81-5 · EC 200-289-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Manufacturers of oral and leave-on products containing glycerin must ensure the raw material used is within the specifications of an accepted pharmacopoeia with respect to diethylene glycol (DEG) impurities (e.g. Glycerin Official Monograph in the most current edition of the USP).

Source:Hotlist restricted entry 42 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Glycolic acid

Canada Hotlist: Glycolic acid

CAS 79-14-1 · EC 201-180-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Alpha-hydroxy acids ".

Source:Hotlist restricted entry 43 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Human origin, substance of

Canada Hotlist: Human origin, substance of

CAS 73049-73-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Human placental extracts; Human placental enzymes; Human placental lipids; Human placental protein; Human umbilical extract; Hydrolyzed human placental protein; Hydrolyzed keratin from human hair; Lyophilized human placental extract | Manufacturers using substances of human origin must provide the following information to Health Canada: Source of the substance; A description of the method of production; Quality control data, particularly those relating to microbial limits (including viruses) and the absence of estrogenic substances; Product labelling.

Source:Hotlist restricted entry 44 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Hydrogen peroxide

Canada Hotlist: Hydrogen peroxide

CAS 7722-84-1 · EC 231-765-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Peroxide and peroxide-generating compounds ".

Source:Hotlist restricted entry 45 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Hydroquinone

Canada Hotlist: Hydroquinone

CAS 123-31-9 · EC 204-617-8

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: 1,4-Dihydroxybenzene | a) Oxidizing colouring agent for hair dyes | b) Nail products | c) Cyanoacrylate adhesive products for eyelash and eyebrow extensions · Maximum concentration: a) 0.3% | b) 0.1% If hydroquinone and p-hydroxyanisole are used in the same product, the total concentration of the 2 ingredients may not exceed 0.1% | c) 0.1% · Warnings: a) "Avoid skin contact" "Do not use to dye eyelashes or eyebrows" "Rinse eyes immediately if the product comes into contact with eyes" | b) "Avoid skin contact" "Read directions carefully before using" | c) "Avoid skin contact" "Read directions carefully before using"

Source:Hotlist restricted entry 46 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Isobutane

Canada Hotlist: Isobutane

CAS 75-28-5 · EC 200-857-2

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Maximum concentration: 0.1% w/w of 1,3-butadiene (106-99-0)

Source:Hotlist restricted entry 47 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Keratin

Canada Hotlist: Keratin

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Human origin, substances of ".

Source:Hotlist restricted entry 48 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Lactic acid

Canada Hotlist: Lactic acid

CAS 50-21-5 · EC 200-018-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Alpha-hydroxy acids ".

Source:Hotlist restricted entry 49 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Magnesium peroxide

Canada Hotlist: Magnesium peroxide

CAS 1335-26-8 · EC 215-627-7 / 238-438-1

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Peroxide and peroxide-generating compounds ".

Source:Hotlist restricted entry 50 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30