Aluminum chlorohydrate and its associated complexes
Canada Hotlist: Aluminum chlorohydrate and its associated complexes
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Regulatory decision and full conditions
- Status
- Restricted
- Legal role
- Official guidance
- Regulatory summary
- Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
- Conditions and restrictions
- Synonyms or related compounds: Aluminum chlorohydrate; Aluminum chlorohydrex PEG; Aluminum chlorohydrex PG; Aluminum dichlorohydrate; Aluminum dichlorohydrex PEG; Aluminum dichlorohydrex PG; Aluminum sesquichlorohydrate; Aluminum sesquichlorohydrex PEG; Aluminum sesquichlorohydrex PG | a) Not permitted in combination with aluminum chloride, other aluminum chlorohydrate complexes or aluminum zirconium complexes. | b) Deodorants and antiperspirants | c) Deodorants and antiperspirants in aerosol dispensers · Maximum concentration: b,c) 25% (calculated as the anhydrous form). | c) "Discontinue use if rash or irritation occurs." "Do not use on broken skin." "Keep away from face to avoid inhalation and spraying in the eyes." "Keep out of reach of children." · Warnings: b) "Discontinue use if rash or irritation occurs." "Do not use on broken skin."
Substance identity
- Official source name
- Aluminum chlorohydrate and its associated complexes
- CAS
- 12042-91-0; 1327-41-9; 173762-81-7; 173762-82-8; 10284-64-7; 173720-80-4; 180324-83-8; 11097-68-0; 173763-15-0; 242812-86-8; 173763-16-1; 245090-60-2
- EC
- Not supplied in this source row
- Identity mapping
- Exact CAS: 12042-91-0
- Linked ingredient
- ALUMINUM CHLOROHYDRATE
Linked CosIng identity data
Names and aliases
CosIng description: Dialuminium chloride pentahydroxide
Recorded cosmetic function: ANTIPERSPIRANT, ASTRINGENT, DEODORANT
Function pages:ANTIPERSPIRANT, ASTRINGENT, DEODORANT
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
Canada
Current record1 linked record · 1 with specific conditions
Open supporting recordVerified chemistry for CAS 10284-64-7
Aluminum dichlorohydrate
- IUPAC name
- dialuminum;dichloride;tetrahydroxide
- Molecular formula
- Al2Cl2H4O4
- Molecular weight
- 192.90 g/mol
- Exact mass
- 191.911741 Da
- Monoisotopic mass
- 191.911741 Da
- Topological polar surface area
- 4.0 Ų
- Molecular complexity
- 0.0
- Formal charge
- 0
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 6
- Rotatable bonds
- 0
- Heavy atoms
- 8
- Covalent units
- 8
Names and synonyms reported to PubChem
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-].[Cl-]- InChI
InChI=1S/2Al.2ClH.4H2O/h;;2*1H;4*1H2/q2*+3;;;;;;/p-6- InChIKey
XILPPDQAWPSZIL-UHFFFAOYSA-H
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | No exact record | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 11097-68-0
Aluminum Sesquichlorohydrate
- IUPAC name
- aluminum;chloride;hydroxide;hydrate
- Molecular formula
- AlClH3O2+
- Formula without charge
- AlClH3O2
- Molecular weight
- 97.46 g/mol
- Exact mass
- 96.9636954 Da
- Monoisotopic mass
- 96.9636954 Da
- Topological polar surface area
- 2.0 Ų
- Molecular complexity
- 0.0
- Formal charge
- 1
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Covalent units
- 4
Names and synonyms reported to PubChem
16 more reported names
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
O.[OH-].[Al+3].[Cl-]- InChI
InChI=1S/Al.ClH.2H2O/h;1H;2*1H2/q+3;;;/p-2- InChIKey
YCLAMANSVUJYPT-UHFFFAOYSA-L
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Carcinogen Classification: Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468). Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: Oral (L739) ; inhalation (L739) Source: Toxin and Toxin Target Database (T3DB)
- Health Effects: Aluminum targets the nervous system and causes decreased nervous system performance and is associated with altered function of the blood-brain barrier. The accumulation of aluminum in the body may cause bone or brain diseases. High levels of aluminum have been linked to Alzheimer's disease. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740) Source: Toxin and Toxin Target Database (T3DB)
- Toxicity Summary: The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The decreased phosphate body burden results in osteomalacia (softening of the bones due to defective bone mineralization) and rickets. Aluminum's neurotoxicity is believed to involve several mechanisms. Changes in cytoskeletal protein functions as a results of altered phosphorylation, proteolysis, transport, and synthesis are believed to be one cause. Aluminum may induce neurobehavioral effects by affecting permeability of the blood-brain barrier, cholinergic activity, signal transduction pathways, lipid peroxidation, and impair neuronal glutamate nitric oxide-cyclic GMP pathway, as well as interfere with metabolism of essential trace elements because of similar coordination chemistries and consequent competitive interactions. It has been suggested that aluminum's interaction with estrogen receptors increases the expression of estrogen-related genes and thereby contributes to the progression of breast cancer (A235), but studies have not been able to establish a clear link between aluminum and increased risk of brea Source: Toxin and Toxin Target Database (T3DB)
- Uses: Aluminium chlorohydrate is used in deodorants and antiperspirants and as a flocculant in water purification. (L746) Source: Toxin and Toxin Target Database (T3DB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 173762-82-8
Aluminum Chlorohydrex Propylene Glycol
- IUPAC name
- dialuminum;propane-1,2-diol;chloride;pentahydroxide;hydrate
- Molecular formula
- C3H15Al2ClO8
- Molecular weight
- 268.56 g/mol
- Exact mass
- 268.008622 Da
- Monoisotopic mass
- 268.008622 Da
- Topological polar surface area
- 46.5 Ų
- Molecular complexity
- 20.0
- Formal charge
- 0
- Hydrogen-bond donors
- 8
- Hydrogen-bond acceptors
- 9
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Covalent units
- 10
Names and synonyms reported to PubChem
4 more reported names
External database identifiers
- EPA DTXSID:DTXSID70938427
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 1
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
CC(CO)O.O.[OH-].[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-]- InChI
InChI=1S/C3H8O2.2Al.ClH.6H2O/c1-3(5)2-4;;;;;;;;;/h3-5H,2H2,1H3;;;1H;6*1H2/q;2*+3;;;;;;;/p-6- InChIKey
KNXDJTLIRRQLBE-UHFFFAOYSA-H
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 173763-15-0
Aluminum Sesquichlorohydrate
- IUPAC name
- aluminum;chloride;hydroxide;hydrate
- Molecular formula
- AlClH3O2+
- Formula without charge
- AlClH3O2
- Molecular weight
- 97.46 g/mol
- Exact mass
- 96.9636954 Da
- Monoisotopic mass
- 96.9636954 Da
- Topological polar surface area
- 2.0 Ų
- Molecular complexity
- 0.0
- Formal charge
- 1
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Covalent units
- 4
Names and synonyms reported to PubChem
16 more reported names
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
O.[OH-].[Al+3].[Cl-]- InChI
InChI=1S/Al.ClH.2H2O/h;1H;2*1H2/q+3;;;/p-2- InChIKey
YCLAMANSVUJYPT-UHFFFAOYSA-L
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 173763-16-1
Aluminum sesquichlorohydrex propylene glycol
- IUPAC name
- aluminum;propane-1,2-diol;chloride;hydroxide;hydrate
- Molecular formula
- C3H11AlClO4+
- Formula without charge
- C3H11AlClO4
- Molecular weight
- 173.55 g/mol
- Exact mass
- 173.0161249 Da
- Monoisotopic mass
- 173.0161249 Da
- Topological polar surface area
- 42.5 Ų
- Molecular complexity
- 20.0
- Formal charge
- 1
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 9
- Covalent units
- 5
Names and synonyms reported to PubChem
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 1
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
CC(CO)O.O.[OH-].[Al+3].[Cl-]- InChI
InChI=1S/C3H8O2.Al.ClH.2H2O/c1-3(5)2-4;;;;/h3-5H,2H2,1H3;;1H;2*1H2/q;+3;;;/p-2- InChIKey
SJXYSRSHDPPYIU-UHFFFAOYSA-L
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 180324-83-8
Aluminum Dichlorohydrex Propylene Glycol
- IUPAC name
- dialuminum;propane-1,2-diol;dichloride;tetrahydroxide;hydrate
- Molecular formula
- C3H14Al2Cl2O7
- Molecular weight
- 287.01 g/mol
- Exact mass
- 285.974735 Da
- Monoisotopic mass
- 285.974735 Da
- Topological polar surface area
- 45.5 Ų
- Molecular complexity
- 20.0
- Formal charge
- 0
- Hydrogen-bond donors
- 7
- Hydrogen-bond acceptors
- 9
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Covalent units
- 10
Names and synonyms reported to PubChem
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 1
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
CC(CO)O.O.[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-].[Cl-]- InChI
InChI=1S/C3H8O2.2Al.2ClH.5H2O/c1-3(5)2-4;;;;;;;;;/h3-5H,2H2,1H3;;;2*1H;5*1H2/q;2*+3;;;;;;;/p-6- InChIKey
WPOOHXKFKJIYGH-UHFFFAOYSA-H
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- Health Canada Cosmetic Ingredient Hotlist
- Source reference
- Hotlist restricted entry 10
- Source record ID
restricted:10- Source version
- Health Canada Hotlist 2025-08-13
- Source language
- English
- Translation status
- Original is English
- Source updated
- 2025-08-13
- Snapshot checked
- 2026-08-30 04:07 UTC
- Validation method
- strict HTML tables t1=490 and t2=90
- SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a
Registered dataset notes
- Dataset coverage
- Administrative prohibitions, restrictions, conditions and warning requirements
- Authority note
- Official Health Canada compliance indicator; not a complete safety clearance
How this record fits the market dataset
Status distribution
Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
Canada market context
Complete Hotlist snapshot
Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.
Verification checklist
- Search English/French names and CAS identifiers.
- Apply every restriction, concentration and label warning.
- Check Food and Drugs Act/Cosmetic Regulations requirements.
- Recheck the current Hotlist before notification or sale.
Official market sources
- Health Canada Cosmetic Ingredient HotlistOfficial Health Canada compliance indicator; not a complete safety clearance
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Aluminum chlorohydrate and its associated complexes” and every CAS/EC identifier refer to the material in your supplier specification.
- Search English/French names and CAS identifiers.
- Apply every restriction, concentration and label warning.
- Check Food and Drugs Act/Cosmetic Regulations requirements.
- Recheck the current Hotlist before notification or sale.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECNot supplied
- Separate condition textAvailable
- Effective dateNot supplied
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Aluminum chlorohydrate and its associated complexes. Hotlist restricted entry 10. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/500/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for Canada
This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.
Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.
How to interpret the legal role
The authority uses this source as compliance guidance; the underlying legislation remains controlling.
Evidence on this page
- Recorded outcome: Restricted
- Legal role: Official guidance
- Source version: Health Canada Hotlist 2025-08-13
What it does not prove
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source