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Coal tar dye

Canada Hotlist: Coal tar dye

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

All Canada recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Restricted
Legal role
Official guidance
Regulatory summary
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions and restrictions
Synonyms or related compounds: Toluene-2,5-diamine; Toluene-2,5-diamine sulfate; See also “ p -Phenylenediamine and its salts ” | a) Not permitted in the area of the eye as indicated in section 14 of the Cosmetic Regulations. | b) In hair dyes as indicated in section 22 of the Cosmetic Regulations. · Warnings: On the inner label and the outer label of the cosmetic: "CAUTION: this product contains ingredients that may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dying the eyelashes or eyebrows. To do so may cause blindness." Instructions to the following effect accompany each package of hair dye: The preparation may cause serious inflammation of the skin in some persons, and a preliminary test should always be carried out to determine whether or not special sensitivity exists; and To make the test, a small area of skin behind the ear or on the inner surface of the forearm should be cleansed, using either soap and water or alcohol, and a small quantity of the hair dye, as prepared for use, should be applied to the area and allowed to dry. After 24 hours, the area should be washed gently with soap and water. If no irritation or inflammation is apparent, it is usually assumed that no hypersensitivity to the dye exists. The test should, however, be carried out before each application. On no account should the hair dye be used for dyeing eyebrows or eyelashes as severe inflammation of the eye or even blindness may result."

Substance identity

Official source name
Coal tar dye
CAS
95-70-5; 615-50-9
EC
Not supplied in this source row
Identity mapping
Exact CAS: 95-70-5
Linked ingredient
TOLUENE-2,5-DIAMINE
Search this identity across the siteCAS 95-70-5CAS 615-50-9

Linked CosIng identity data

Names and aliases

TOLUENE-2,5-DIAMINE

CosIng description: 2-Methyl-p-phenylenediamine (CI 76042)

EU inventory restriction note: III/9a

Recorded cosmetic function: HAIR DYEING

Function pages:HAIR DYEING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

8 market datasets
PubChem 2D chemical structure for CAS 615-50-9
CAS 615-50-9PubChem CID 22856

Verified chemistry for CAS 615-50-9

2,5-Diaminotoluene sulfate

2,5-diaminotoluene sulfate is an organic sulfate salt obtained by combining 2,5-diaminotoluene with one molar equivalent of sulfuric acid; occurs as an intermediate during hair dye formulation. It has a role as an allergen. It is a diamine and an organic sulfate salt. It is functionally related to a 2-methyl-1,4-phenylenediamine. — ChEBI

IUPAC name
2-methylbenzene-1,4-diamine;sulfuric acid
Molecular formula
C7H12N2O4S
Molecular weight
220.25 g/mol
Exact mass
220.05177804 Da
Monoisotopic mass
220.05177804 Da
Topological polar surface area
135.0 Ų
Molecular complexity
174.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Rotatable bonds
0
Heavy atoms
14
Covalent units
2

Names and synonyms reported to PubChem

Fouramine STDToluene-2,5-diamine sulfateC.I. Oxidation Base 4p-Toluylenediamine sulfate2-Methyl-1,4-benzenediamine sulfateCI Oxidation Base 4Toluene-2,5-diamine, sulfateRodol BLFX
16 more reported names
para-Toluenediamine sulphateNCI-C01832CI 76043para-Toluylenediamine sulphateC.I. 76043Toluylene-2,5-diamine sulphatep-Toluenediamine sulphate2,5-TDSp-Tolylenediamine sulphatep-Toluylenediamine sulphate2,5-Diaminotoluene sulphate8PSD05SPE22-Methyl-para-phenylenediamine sulphateToluene-2,5-diamine, sulfate (1:1)JAROCOL TDSCHEBI:156544
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
CC1=C(C=CC(=C1)N)N.OS(=O)(=O)O
InChI
InChI=1S/C7H10N2.H2O4S/c1-5-4-6(8)2-3-7(5)9;1-5(2,3)4/h2-4H,8-9H2,1H3;(H2,1,2,3,4)
InChIKey
KZTWOUOZKZQDMN-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 95-70-5
CAS 95-70-5PubChem CID 7252

Verified chemistry for CAS 95-70-5

2,5-Diaminotoluene

2-methyl-1,4-phenylenediamine is a diamine in which the two amino groups are substituted into toluene at the 2- and 5-positions. It has a role as an allergen. It derives from a hydride of a toluene. — ChEBI

IUPAC name
2-methylbenzene-1,4-diamine
Molecular formula
C7H10N2
Molecular weight
122.17 g/mol
Exact mass
122.084398327 Da
Monoisotopic mass
122.084398327 Da
XLogP3
0.6
Topological polar surface area
52.0 Ų
Molecular complexity
92.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
2
Rotatable bonds
0
Heavy atoms
9
Covalent units
1

Names and synonyms reported to PubChem

Toluene-2,5-diamine2,5-Toluenediaminep-Toluenediamine2-METHYL-1,4-BENZENEDIAMINE4-Amino-2-methylaniline2-Methyl-p-phenylenediamine1,4-Benzenediamine, 2-methyl-p-Toluylendiamine
16 more reported names
Toluylene-2,5-diaminepara-Toluenediaminepara-Tolylenediaminepara-Toluylenediamine2-Methyl-para-phenylenediamineC.I. 7604224JO8Z0RJU1-methyl-2,5-diaminobenzeneCI 76042PARATOLUENEDIAMINE2,5-toluylenediamineRefChem:82755202-442-1p,m-Tolylenediamine2-methyl-1,4-phenylenediamine2-methyl-benzene-1,4-diamine
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
0
3D donor features
2
3D anionic centres
0
3D cationic centres
2
3D conformers
1
Effective 3D rotors
0.0
Machine-readable structure identifiers
SMILES
CC1=C(C=CC(=C1)N)N
InChI
InChI=1S/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3
InChIKey
OBCSAIDCZQSFQH-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Health Canada Cosmetic Ingredient Hotlist
Source reference
Hotlist restricted entry 30
Source record ID
restricted:30
Source version
Health Canada Hotlist 2025-08-13
Source language
English
Translation status
Original is English
Source updated
2025-08-13
Snapshot checked
2026-08-30 04:07 UTC
Validation method
strict HTML tables t1=490 and t2=90
SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a

Registered dataset notes

Dataset coverage
Administrative prohibitions, restrictions, conditions and warning requirements
Authority note
Official Health Canada compliance indicator; not a complete safety clearance
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

580
current Canada records
90
records marked Restricted
580
records from this source version
516
market records with CAS identity

Status distribution

Prohibited: 490Restricted: 90

Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Canada market context

Complete Hotlist snapshot

Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025

All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.

Verification checklist

  1. Search English/French names and CAS identifiers.
  2. Apply every restriction, concentration and label warning.
  3. Check Food and Drugs Act/Cosmetic Regulations requirements.
  4. Recheck the current Hotlist before notification or sale.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Coal tar dye” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search English/French names and CAS identifiers.
  3. Apply every restriction, concentration and label warning.
  4. Check Food and Drugs Act/Cosmetic Regulations requirements.
  5. Recheck the current Hotlist before notification or sale.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECNot supplied
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

The record cites Hotlist restricted entry 30, source version Health Canada Hotlist 2025-08-13. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Coal tar dye. Hotlist restricted entry 30. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/520/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Canada

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The authority uses this source as compliance guidance; the underlying legislation remains controlling.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Official guidance
  • Source version: Health Canada Hotlist 2025-08-13

What it does not prove

The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source