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Calcium peroxide

Canada Hotlist: Calcium peroxide

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

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Regulatory decision and full conditions

Status
Restricted
Legal role
Official guidance
Regulatory summary
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions and restrictions
Synonyms or related compounds: Calcium dioxide | See " Peroxide and peroxide-generating compounds ".

Substance identity

Official source name
Calcium peroxide
CAS
1305-79-9
EC
215-139-4
Identity mapping
cas_number
Linked ingredient
CALCIUM PEROXIDE
Search this identity across the siteCAS 1305-79-9EC 215-139-4

Linked CosIng identity data

Names and aliases

CALCIUM PEROXIDE

CosIng description: Calcium peroxide

EU inventory restriction note: III/12

Recorded cosmetic function: OXIDISING

Function pages:OXIDISING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

2 market datasets
PubChem 2D chemical structure for CAS 1305-79-9
CAS 1305-79-9PubChem CID 14779

Verified chemistry for CAS 1305-79-9

Calcium peroxide

Calcium peroxide is a member of calcium oxides. — ChEBI

IUPAC name
calcium peroxide
Molecular formula
CaO2
Molecular weight
72.08 g/mol
Exact mass
71.9524201 Da
Monoisotopic mass
71.9524201 Da
Topological polar surface area
46.1 Ų
Molecular complexity
2.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Rotatable bonds
0
Heavy atoms
3
Covalent units
2

Names and synonyms reported to PubChem

Calcium dioxideCalperCalper GCalcium peroxide (Ca(O2))7FRO2ENO91CHEBI:48233RefChem:122888215-139-4
13 more reported names
684-873-9calcium;peroxideUNII-7FRO2ENO91peroxidocalciumCalciumperoxidKalziumperoxidHSDB 965cyc-CaO2EINECS 215-139-4UN1457Ca(O2)(eta~2~-Dioxidanediido)calciumCalcium peroxide [UN1457] [Oxidizer]
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
[O-][O-].[Ca+2]
InChI
InChI=1S/Ca.O2/c;1-2/q+2;-2
InChIKey
LHJQIRIGXXHNLA-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match14779

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: INHALATION: remove to fresh air.; EYES: flush with water for 15 min. and consult physician.; SKIN: flush with water.; INGESTION: give large amounts of water. (USCG, 1999) Source: CAMEO Chemicals
  • ERG2024, Guide 140 (Calcium peroxide): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H272 (97.1%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]; H315 (94.3%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (94.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (94.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P210, P220, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 140 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P220, P264+P265, P280, P305+P354+P338, P317, P370+P378, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Toxicity Summary: IDENTIFICATION AND USE: Calcium peroxide is white or yellowish powder. It is used as a stabilizer for rubber. Other uses including seed disinfectant, dentifrices, dough conditioners, antiseptic, bleaching of oils, modification of starches, high temperature oxidation. An important application of calcium peroxide is for curing the polysulfide sealants used in double glazing window units. Calcium peroxide is also used at several gold mines in Australia to increase recovery of gold and reduce the consumption of cyanide. Calcium peroxide has been identified as being used in hydraulic fracturing as a breaker. HUMAN EXPOSURE AND TOXICITY: Contact with calcium peroxide can severely irritate and may burn the skin and eyes. Exposure can irritate the eyes, nose, and throat. Prolonged exposure can damage the skin. Higher levels of calcium peroxide can irritate the lungs causing coughing and/or shortness of breath. Still higher exposures may cause a buildup of fluid in the lungs (pulmonary edema). This can cause death. ANIMAL STUDIES: Experiments with calcium peroxide revealed that the compound is not toxic to dogs treated orally. ECOTOXICITY STUDIES: New method was proposed for increasing the Source: Hazardous Substances Data Bank (HSDB)
  • Sources/Uses: Used as a rubber stabilizer, antiseptic, seed disinfectant, starch modifier, sewage deodorizer, and wastewater dechlorinator; Also used for dentifrices; in dough conditioners; for bleaching of oils; in high temperature oxidations; for curing the polysulfide sealants used in double glazing window units; to increase recovery of gold and reduce the consumption of cyanide (at gold mines); to improve the bioremediation of soils contaminated with creosote or kerosene; for removing metal ions from acidic waste streams such as coal ash leachate and acid mine drainage; in the cultivation of tomatoes, cucumbers, tobacco, and prawns (Japan); [HSDB] Used as a flour treatment agent; [JECFA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry]; Sewer and Wastewater Treatment [Category: Industry]; Metal Extraction and Refining [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: Stabilizer for rubber. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Seed disinfectant, dentifrices, dough conditioners, antiseptic, bleaching of oils, modification of starches, high temperature oxidation. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Calcium peroxide is used as oxygen source in the leaching of gold and silver ores with cyanide to improve precious metal recovery and leaching kinetics. A relatively new application for CaO2 is as a peroxide source in toothpaste and dental chewing gum products. Calcium peroxide is also used in limited quantities as a hardening accelerator for sulfide rubber, as dough conditioner in the baking industry, and as a nontoxic disinfectant for seed and grain. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: An important application of calcium peroxide is for curing the polysulfide sealants used in double glazing window units. Calcium peroxide is also used at several gold mines in Australia to increase recovery of gold and reduce the consumption of cyanide. Calcium peroxide (PermeOx) is also used to improve the bioremediation of soils contaminated with creosote or kerosene, to deodorize sewage sludges and wastewater, and to dechlorinate wastewater and effluents. A special formulation of calcium peroxide ... is used for removing metal ions from acidic waste streams such as coal ash leachate and acid mine drainage. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for CALCIUM PEROXIDE (7 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Health Canada Cosmetic Ingredient Hotlist
Source reference
Hotlist restricted entry 22
Source record ID
restricted:22
Source version
Health Canada Hotlist 2025-08-13
Source language
English
Translation status
Original is English
Source updated
2025-08-13
Snapshot checked
2026-08-30 04:07 UTC
Validation method
strict HTML tables t1=490 and t2=90
SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a

Registered dataset notes

Dataset coverage
Administrative prohibitions, restrictions, conditions and warning requirements
Authority note
Official Health Canada compliance indicator; not a complete safety clearance
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

580
current Canada records
90
records marked Restricted
580
records from this source version
516
market records with CAS identity

Status distribution

Prohibited: 490Restricted: 90

Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Canada market context

Complete Hotlist snapshot

Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025

All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.

Verification checklist

  1. Search English/French names and CAS identifiers.
  2. Apply every restriction, concentration and label warning.
  3. Check Food and Drugs Act/Cosmetic Regulations requirements.
  4. Recheck the current Hotlist before notification or sale.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Calcium peroxide” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search English/French names and CAS identifiers.
  3. Apply every restriction, concentration and label warning.
  4. Check Food and Drugs Act/Cosmetic Regulations requirements.
  5. Recheck the current Hotlist before notification or sale.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

The record cites Hotlist restricted entry 22, source version Health Canada Hotlist 2025-08-13. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Calcium peroxide. Hotlist restricted entry 22. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/512/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Canada

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The authority uses this source as compliance guidance; the underlying legislation remains controlling.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Official guidance
  • Source version: Health Canada Hotlist 2025-08-13

What it does not prove

The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source