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Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts

Canada Hotlist: Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

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Regulatory decision and full conditions

Status
Restricted
Legal role
Official guidance
Regulatory summary
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions and restrictions
Synonyms or related compounds: Citric acid; Glycolic acid; Lactic acid; Malic acid; Mandelic acid; Tartaric acid; Ammonium glycolate; Sodium citrate; Hydroxycaprylic acid; Mixed fruit acids; Gluconolactone; Ammonium gluconate; Lactobionic acid; Calcium lactobionate | a) Products for use on the skin for consumer use Manufacturer or importer to provide pH levels | b) Products for use on the skin for professional use Manufacturer or importer to provide evidence of safety, including: pH levels AHA concentrations directions for use clinical studies demonstrating minimal skin irritation | c) Products intended to be diluted in bath water may contain levels of AHAs exceeding 10% | d) Other cosmetics | e) Any cosmetics · Maximum concentration: a) Between 3% and 18% total mono-AHA equivalents with a pH equal to or greater than 3.5 | b) Between 18% and 30% total mono-AHA equivalents and/or a pH between 3.0 to 3.5 | d) Between 3% and 30% total mono-AHA equivalents with a pH equal to or greater than 3.0 | 3% · Warnings: a) and b) "Use only as directed" "Avoid contact with the eyes" "If irritation persists, discontinue use and consult a physician" "It is recommended that prior to exposure to the sun, users cover areas where AHAs have been applied with sunscreen" Product labels should contain appropriate directions regarding frequency and/or duration of use b only) "For professional use only" | d) "Use only as directed" "Avoid contact with eyes" "Discontinue use if rash or irritation occurs"

Substance identity

Official source name
Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts
CAS
77-92-9; 79-14-1; 50-21-5; 133-37-9; 6915-15-7; 79-33-4; 5949-29-1; 617-73-2; 90-64-2; 35249-89-9
EC
Not supplied in this source row
Identity mapping
Exact CAS: 77-92-9
Linked ingredient
CITRIC ACID
Search this identity across the siteCAS 77-92-9CAS 79-14-1CAS 50-21-5CAS 133-37-9CAS 6915-15-7CAS 79-33-4CAS 5949-29-1CAS 617-73-2CAS 90-64-2CAS 35249-89-9

Linked CosIng identity data

Names and aliases

CITRIC ACIDcitric acidacidum citricum

CosIng description: 2-Hydroxy-1,2,3-propanetricarboxylic acid

EU inventory restriction note: V/59

Recorded cosmetic function: BUFFERING, CHELATING, FRAGRANCE

Function pages:BUFFERING, CHELATING, FRAGRANCE

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

9 market datasets
PubChem 2D chemical structure for CAS 35249-89-9
CAS 35249-89-9PubChem CID 169677

Verified chemistry for CAS 35249-89-9

Ammonium Glycolate

IUPAC name
azanium 2-hydroxyacetate
Molecular formula
C2H7NO3
Molecular weight
93.08 g/mol
Exact mass
93.042593085 Da
Monoisotopic mass
93.042593085 Da
Topological polar surface area
61.4 Ų
Molecular complexity
34.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
0
Heavy atoms
6
Covalent units
2

Names and synonyms reported to PubChem

ammonium hydroxyacetateAcetic acid, hydroxy-, monoammonium saltHydroxyacetic acid, ammoniuum salt8G1X5P7GILGLICONOL LAcetic acid, 2-hydroxy-, ammonium salt (1:1)EC 609-106-7HYDROXYACETIC ACID AMMONIUM SALT
11 more reported names
DuPont Glyclean OSRefChem:557727AMMONIUM GLYCOLATE [INCI]AMMONIUM HYDROXYACETIC ACIDAcetic acid, hydroxy, monoammonium saltAcetic acid, 2hydroxy, ammonium salt (1:1)609-106-7azanium;2-hydroxyacetateAmmonium 2-hydroxyacetateUNII-8G1X5P7GILHydroxy acetic acid ammonium salt
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)[O-])O.[NH4+]
InChI
InChI=1S/C2H4O3.H3N/c3-1-2(4)5;/h3H,1H2,(H,4,5);1H3
InChIKey
UBKBVPONTPMQQW-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 50-21-5
CAS 50-21-5PubChem CID 612

Verified chemistry for CAS 50-21-5

Lactic Acid

2-hydroxypropanoic acid is a 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. It has a role as a Daphnia magna metabolite and an algal metabolite. It is functionally related to a propionic acid. It is a conjugate acid of a lactate. — ChEBI

IUPAC name
2-hydroxypropanoic acid
Molecular formula
C3H6O3
Molecular weight
90.08 g/mol
Exact mass
90.031694049 Da
Monoisotopic mass
90.031694049 Da
XLogP3
-0.7
Topological polar surface area
57.5 Ų
Molecular complexity
59.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
6
Covalent units
1

Names and synonyms reported to PubChem

DL-Lactic acid2-hydroxypropionic acidMilk acidTonsillosanRacemic lactic acidOrdinary lactic acidAcidum lacticumEthylidenelactic acid
16 more reported names
LactovaganMilchsaeureLactic acid, dl-Kyselina mlecnaLacticum acidumPropanoic acid, 2-hydroxy-598-82-3alpha-Hydroxypropionic acidLactic acid USPAethylidenmilchsaeure(RS)-2-HydroxypropionsaeureFEMA No. 2611MilchsaureLurexPropionic acid, 2-hydroxy-SY-83
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
0
3D hydrophobes
0
3D acceptor features
3
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
4
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
CC(C(=O)O)O
InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)
InChIKey
JVTAAEKCZFNVCJ-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 5949-29-1
CAS 5949-29-1PubChem CID 22230

Verified chemistry for CAS 5949-29-1

2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1)

IUPAC name
2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
Molecular formula
C6H10O8
Molecular weight
210.14 g/mol
Exact mass
210.03756727 Da
Monoisotopic mass
210.03756727 Da
Topological polar surface area
133.0 Ų
Molecular complexity
227.0
Formal charge
0
Hydrogen-bond donors
5
Hydrogen-bond acceptors
8
Rotatable bonds
5
Heavy atoms
14
Covalent units
2

Names and synonyms reported to PubChem

Citric acid monohydrateCitric acid hydrateCITRIC ACID, MONOHYDRATE1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydratecitric acid;hydrate2968PHW8QP1,2,3-Propanetricarboxylic acid, 2-hydroxy-, hydrate (1:1)Acidum citricum monohydrate
16 more reported names
Citiric acidSoothe ChewableSurface WipesStop HairAlphacide ActivatorPURILABGREEN FRESHNATURE CLEANRefChem:6528AQUACETIC-30CITRACID-50W.SKIN TREEMON CLEANSING WATERCleaning Solution for Hemodialysis MachinesDesinfectant Solution for Hemodialysis Machine2-hydroxypropane-1,2,3-tricarboxylic acid monohydrateKID-CLEAN Epiguard (Herbage Basis germ Growth InhibitsSolution)
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C(C(=O)O)C(CC(=O)O)(C(=O)O)O.O
InChI
InChI=1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
InChIKey
YASYEJJMZJALEJ-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 617-73-2
CAS 617-73-2PubChem CID 94180

Verified chemistry for CAS 617-73-2

Hydroxycaprylic Acid

IUPAC name
2-hydroxyoctanoic acid
Molecular formula
C8H16O3
Molecular weight
160.21 g/mol
Exact mass
160.109944368 Da
Monoisotopic mass
160.109944368 Da
XLogP3
2.0
Topological polar surface area
57.5 Ų
Molecular complexity
112.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
6
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

2-Hydroxycaprylic acidOctanoic acid, 2-hydroxy-alpha-Hydroxycaprylic acidalpha-Hydroxyoctanoic acidDL-2-Hydroxyoctanoic acidDL-2-Hydroxycaprylic acid.alpha.-Hydroxycaprylic acid0R6X0G0S8A
16 more reported names
.alpha.-Hydroxy-n-caprylic acidEINECS 210-524-3NSC 189703NSC-189703alpha-Hydroxy-n-caprylic acidCHEBI:86543alpha-HCA acidRefChem:789453HYDROXYCAPRYLIC ACID [INCI](+-)-2-HYDROXYOCTANOIC ACID(+-)-ALPHA-HYDROXYCAPRYLIC ACID(+-)-.ALPHA.-HYDROXYCAPRYLIC ACID210-524-32-Hydroxy-n-octanoic Acid2-hydroxy caprylic acid2-hydroxy-octanoic acid
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
7
3D rings
0
3D hydrophobes
2
3D acceptor features
3
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
10
Effective 3D rotors
6.0
Machine-readable structure identifiers
SMILES
CCCCCCC(C(=O)O)O
InChI
InChI=1S/C8H16O3/c1-2-3-4-5-6-7(9)8(10)11/h7,9H,2-6H2,1H3,(H,10,11)
InChIKey
JKRDADVRIYVCCY-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 6915-15-7
CAS 6915-15-7PubChem CID 525

Verified chemistry for CAS 6915-15-7

Malic Acid

IUPAC name
2-hydroxybutanedioic acid
Molecular formula
C4H6O5
Molecular weight
134.09 g/mol
Exact mass
134.02152329 Da
Monoisotopic mass
134.02152329 Da
XLogP3
-1.3
Topological polar surface area
94.8 Ų
Molecular complexity
129.0
Formal charge
0
Hydrogen-bond donors
3
Hydrogen-bond acceptors
5
Rotatable bonds
3
Heavy atoms
9
Covalent units
1

Names and synonyms reported to PubChem

hydroxysuccinic acidButanedioic acid, hydroxy-Malic acid, DL-Kyselina jablecnahydroxybutanedioic acidPomalus acidalpha-Hydroxysuccinic acidDeoxytetraric acid
16 more reported names
HydroxybutandisaeureMonohydroxybernsteinsaeureSuccinic acid, hydroxy-(+-)-Malic acidMalicum acidumPomalous acidd,l-malic acidFEMA No. 26552-Hydroxyethane-1,2-dicarboxylic acidKyselina hydroxybutandiova(+-)-Hydroxysuccinic acidNSC-25941817L1N4CKPINS NO.296E296INS NO. 296
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
8
3D rings
0
3D hydrophobes
0
3D acceptor features
5
3D donor features
1
3D anionic centres
2
3D cationic centres
0
3D conformers
10
Effective 3D rotors
3.0
Machine-readable structure identifiers
SMILES
C(C(C(=O)O)O)C(=O)O
InChI
InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
InChIKey
BJEPYKJPYRNKOW-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 77-92-9
CAS 77-92-9PubChem CID 311

Verified chemistry for CAS 77-92-9

Citric Acid

Citric acid is a tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms. It has a role as a calcium chelator, an antimicrobial agent, a chelator, a food acidity regulator and a fundamental metabolite. It is a conjugate acid of a citrate anion and a citrate(1-). — ChEBI

IUPAC name
2-hydroxypropane-1,2,3-tricarboxylic acid
Molecular formula
C6H8O7
Molecular weight
192.12 g/mol
Exact mass
192.02700259 Da
Monoisotopic mass
192.02700259 Da
XLogP3
-1.7
Topological polar surface area
132.0 Ų
Molecular complexity
227.0
Formal charge
0
Hydrogen-bond donors
4
Hydrogen-bond acceptors
7
Rotatable bonds
5
Heavy atoms
13
Covalent units
1

Names and synonyms reported to PubChem

Citric acid, anhydrousAcilettenAnhydrous citric acidCitroCitrettenCitric acid anhydrousChemfillHydrocerol A
16 more reported names
1,2,3-Propanetricarboxylic acid, 2-hydroxy-2-hydroxy-1,2,3-propanetricarboxylic acidKyselina citronova2-Hydroxytricarballylic acidbeta-Hydroxytricarballylic acid3-Carboxy-3-hydroxypentane-1,5-dioic acidFEMA No. 2306FEMA Number 2306Citric acid,anhydrousCitricum acidumCitric acid monoglycerideAcidum citricumCitric acid bpXF417D3PSLNSC-30279Citric acid,hydrous
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
11
3D rings
0
3D hydrophobes
0
3D acceptor features
7
3D donor features
1
3D anionic centres
3
3D cationic centres
0
3D conformers
10
Effective 3D rotors
5.0
Machine-readable structure identifiers
SMILES
C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChI
InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChIKey
KRKNYBCHXYNGOX-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 79-14-1
CAS 79-14-1PubChem CID 757

Verified chemistry for CAS 79-14-1

Glycolic Acid

IUPAC name
2-hydroxyacetic acid
Molecular formula
C2H4O3
Molecular weight
76.05 g/mol
Exact mass
76.016043985 Da
Monoisotopic mass
76.016043985 Da
XLogP3
-1.1
Topological polar surface area
57.5 Ų
Molecular complexity
40.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
5
Covalent units
1

Names and synonyms reported to PubChem

hydroxyacetic acidHydroxyethanoic acidGlycollic acidglycolatealpha-Hydroxyacetic acid2-Hydroxyethanoic acidKyselina glykolovaKyselina hydroxyoctova
16 more reported names
GLYCOLLATENSC-1660WT12SX38SCHEBI:174974-03-00-00571 (Beilstein Handbook Reference)2-oxonioacetateCHEBI:29805OceanBlu BarrierOceanBlu Pre-PostRefChem:5867Jungshea Glycolic Acid PadsInstaMix Glycolic Concentratepari 30% Glycolic Acid Peelpari 70% Glycolic Acid PeelGlycolic Acid 7% Toning SolutionGLYCOLIC Acid 35 Skin Chemical Peel
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
0
3D hydrophobes
0
3D acceptor features
3
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
2
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
C(C(=O)O)O
InChI
InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChIKey
AEMRFAOFKBGASW-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 79-33-4
CAS 79-33-4PubChem CID 107689

Verified chemistry for CAS 79-33-4

L-Lactic Acid

IUPAC name
(2S)-2-hydroxypropanoic acid
Molecular formula
C3H6O3
Molecular weight
90.08 g/mol
Exact mass
90.031694049 Da
Monoisotopic mass
90.031694049 Da
XLogP3
-0.7
Topological polar surface area
57.5 Ų
Molecular complexity
59.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
1
Heavy atoms
6
Covalent units
1

Names and synonyms reported to PubChem

L-(+)-Lactic acid(S)-Lactic acid(S)-2-Hydroxypropanoic acidSarcolactic acid(S)-2-Hydroxypropionic acid(+)-Lactic acidParalactic acid(S)-(+)-Lactic acid
16 more reported names
Lactic acid, L-TisulacPropanoic acid, 2-hydroxy-, (2S)-Sarcolacticum acidumL-(+)-alpha-Hydroxypropionic acidF9S9FFU82NCHEBI:422Lactisan WinterKey DermolacPleo SanuvisL Lactic AcidClO2-C ActivatorRefChem:55440Chlorine Dioxide Teat DipJabon antiseptico a base de acido lactico201-196-2
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
1
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
0
3D hydrophobes
0
3D acceptor features
3
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
3
Effective 3D rotors
1.0
Machine-readable structure identifiers
SMILES
C[C@@H](C(=O)O)O
InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
InChIKey
JVTAAEKCZFNVCJ-REOHCLBHSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 90-64-2
CAS 90-64-2PubChem CID 1292

Verified chemistry for CAS 90-64-2

Mandelic Acid

IUPAC name
2-hydroxy-2-phenylacetic acid
Molecular formula
C8H8O3
Molecular weight
152.15 g/mol
Exact mass
152.047344113 Da
Monoisotopic mass
152.047344113 Da
XLogP3
0.6
Topological polar surface area
57.5 Ų
Molecular complexity
138.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
2
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

dl-Mandelic acidPhenylglycolic acidParamandelic acidAmygdalic acidUromalineRacemic mandelic acidPhenylhydroxyacetic acid(RS)-Mandelic acid
16 more reported names
alpha-Hydroxyphenylacetic acidAcido mandelicoKyselina mandlovaBenzeneacetic acid, alpha-hydroxy-alpha-Hydroxybenzeneacetic acidNSC-7925NH496X0UJXCHEBI:35825RefChem:5982202-007-6611-72-3Almond acid2-Phenylglycolic acidp-Mandelic acidHydroxy(phenyl)acetic acid(+/-)-alpha-Hydroxyphenylacetic acid
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
1
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
6
3D rings
1
3D hydrophobes
0
3D acceptor features
3
3D donor features
1
3D anionic centres
1
3D cationic centres
0
3D conformers
10
Effective 3D rotors
2.0
Machine-readable structure identifiers
SMILES
C1=CC=C(C=C1)C(C(=O)O)O
InChI
InChI=1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChIKey
IWYDHOAUDWTVEP-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Health Canada Cosmetic Ingredient Hotlist
Source reference
Hotlist restricted entry 8
Source record ID
restricted:8
Source version
Health Canada Hotlist 2025-08-13
Source language
English
Translation status
Original is English
Source updated
2025-08-13
Snapshot checked
2026-08-30 04:07 UTC
Validation method
strict HTML tables t1=490 and t2=90
SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a

Registered dataset notes

Dataset coverage
Administrative prohibitions, restrictions, conditions and warning requirements
Authority note
Official Health Canada compliance indicator; not a complete safety clearance
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

580
current Canada records
90
records marked Restricted
580
records from this source version
516
market records with CAS identity

Status distribution

Prohibited: 490Restricted: 90

Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Canada market context

Complete Hotlist snapshot

Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025

All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.

Verification checklist

  1. Search English/French names and CAS identifiers.
  2. Apply every restriction, concentration and label warning.
  3. Check Food and Drugs Act/Cosmetic Regulations requirements.
  4. Recheck the current Hotlist before notification or sale.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search English/French names and CAS identifiers.
  3. Apply every restriction, concentration and label warning.
  4. Check Food and Drugs Act/Cosmetic Regulations requirements.
  5. Recheck the current Hotlist before notification or sale.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECNot supplied
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

The record cites Hotlist restricted entry 8, source version Health Canada Hotlist 2025-08-13. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts. Hotlist restricted entry 8. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/498/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Canada

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The authority uses this source as compliance guidance; the underlying legislation remains controlling.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Official guidance
  • Source version: Health Canada Hotlist 2025-08-13

What it does not prove

The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source