Great Britain cosmetic ingredient regulations
GB rules must be versioned separately from EU rules as they diverge.
- Regulator
- Office for Product Safety and Standards
- Source language
- English
- Coverage version
- GB retained Regulation 1223/2009 schedules, effective 15 August 2026
What this list is
Great Britain carried EU Regulation 1223/2009 onto its own statute book after Brexit and has amended it separately ever since. The two lists started identical and no longer are, which is why a GB check cannot be answered from an EU one.
- 2,329 GB records: 1,758 prohibited, 326 restricted, 245 on a positive list.
- The regulator is the Office for Product Safety and Standards, not the European Commission.
- GB and EU annexes are amended by different bodies on different dates, so they drift apart substance by substance.
- A substance absent from the GB list is not thereby permitted — absence is absence of a record, not a decision.
The Cosmetic Products Enforcement Regulations 2013 kept Regulation 1223/2009 in force in Great Britain after EU exit, so the structure a formulator already knows — Annex II for prohibited substances, Annex III for restricted ones, Annexes IV to VI for colourants, preservatives and UV filters — is the same here. What changed is who amends it. The Office for Product Safety and Standards now does that for Great Britain, and the European Commission does it for the EU, on their own timetables.
That divergence is the practical point of this page. When the Commission adds a substance to Annex II, Great Britain does not follow automatically. The reverse holds too. Two lists that began as one copy now differ entry by entry, and the gap widens with each amendment cycle, so a compliance answer for one market is not evidence for the other even when the substance and the wording look identical.
Northern Ireland is not covered here. Under the Windsor Framework it continues to apply the EU regulation, so a product placed on the market across the whole United Kingdom is answering to two rulebooks at once. Check the EU records for that half.
The 2,329 records below carry the status the GB source gives them and nothing more. Where a record is marked restricted, the concentration limit, product-type condition and warning text come from the source as written; where a substance has no record at all, that means no GB entry was resolved here, not that its use has been considered and allowed.
Checked against
Official ingredient records
2329 matching recordsThimerosal
CAS 54-64-8 · EC 200-210-4
The consolidated GB Cosmetics Regulation lists this record in Annex V.
Conditions: Eye products · 0,007% (of Hg) If mixed with other mercurial compounds authorised by this Regulation, the maximum concentration of Hg remains fixed at 0,007% · Contains Thiomersal
Source:GB Cosmetics Regulation, Annex V, entry 16 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thioacetamide
CAS 62-55-5 · EC 200-541-4
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 742 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thioglycolic acid
CAS 68-11-1 · EC 200-677-4
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: (a) Hair waving or straightening products · (a) 8% 11% · (a) General use ready for use pH 7 to 9,5 Professional use ready for use pH 7 to 9,5 · Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions
Source:GB Cosmetics Regulation, Annex III, entry 2a · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thiophanate-methyl
CAS 23564-05-8 · EC 245-740-7
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1047 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thiophanate-methyl (ISO); dimethyl (1,2- phenylenedicarbamothioyl)biscarbamat; dimethyl 4,4’-(o-phenylene)bis(3- thioallophanate)
CAS 23564-05-8 · EC 245-740-7
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1687 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thiotepa (INN)
CAS 52-24-4 · EC 200-135-7
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 310 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thiourea and its derivatives, with the exception of the one listed in Annex III
CAS 62-56-6 · EC 200-543-5
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 321 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thiuram monosulphides
CAS 97-74-5 · EC 202-605-7
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 353 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thuja Occidentalis Bark Extract;Thuja Occidentalis Leaf;Thuja Occidentalis Leaf Extract;Thuja Occidentalis Leaf Oil;Thuja Occidentalis Stem Extract;Thuja Occidentalis Stem Oil;Thuja Occidentalis Root Extract
CAS 90131-58-1 · EC 290-370-1
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: Peroxide value less than 10 mmoles/L
Source:GB Cosmetics Regulation, Annex III, entry 119 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Thyropropic acid (INN) and its salts
CAS 51-26-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 9 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Titanium Dioxide
CAS 13463-67-7; 1317-70-0; 1317-80-2 · EC 236-675-5; 215-280-1; 215-282-2
The consolidated GB Cosmetics Regulation lists this record in Annex VI.
Conditions: 25%
Source:GB Cosmetics Regulation, Annex VI, entry 27 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Titanium Dioxide (nano)
CAS 13463-67-7; 1317-70-0; 1317-80-2 · EC 236-675-5; 215-280-1; 215-282-2
The consolidated GB Cosmetics Regulation lists this record in Annex VI.
Conditions: 25% · Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: purity ≥ 99%, rutile form, or rutile with up to 5% anatase, with crystalline structure and physical appearance as clusters of spherical, needle, or lanceolate shapes, median particle size based on number size distribution ≥ 30 nm, aspect ratio from 1 to 4,5, and volume specific surface area ≤ 460 m 2 /cm 3 , coated with Silica, Hydrated Silica, Alumina, Aluminium Hydroxide, Aluminium Stearate, Stearic Acid, Trimethoxycaprylylsilane, Glycerin, Dimethicone, Hydrogen Dimethicone, Simethicone, or coated with one of the following combinations: Silica at a maximum concentration of 16% and Cetyl Phosphate at a maximum concentration of 6%, Alumina at a maximum concentration of 7% and Manganese Dioxide at a maximum concentration of 0,7% (not to be used in lip products), Alumina at a maximum concentration of 3% and Triethoxycaprylylsilane at a maximum concentration of 9%, photocatalytic activity ≤ 10% compared to corresponding non-coated or non-doped reference, nanoparticles are photostable in the final formulation. · For face products containing Titanium Dioxide (nano) coated with the combination Alumina and Manganese Dioxide: Not to be used on the lips.
Source:GB Cosmetics Regulation, Annex VI, entry 27a · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Titanium dioxide
CAS 13463-67-7 · EC 236-675-5
The consolidated GB Cosmetics Regulation lists this record in Annex IV.
Conditions: Purity criteria as set out in Commission Directive 95/45/EC (E 171)
Source:GB Cosmetics Regulation, Annex IV, entry 143 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tolboxane (INN)
CAS 2430-46-8
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 177 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tolbutamide (INN)
CAS 64-77-7 · EC 200-594-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 65 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluene
CAS 108-88-3 · EC 203-625-9
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: Nail products · 25 % · Keep out of reach of children To be used by adults only
Source:GB Cosmetics Regulation, Annex III, entry 185 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluene-2,5-DiamineToluene-2,5-Diamine Sulfate
CAS 95-70-5; 615-50-9 · EC 202-442-1; 210-431-8
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: (a) Hair dye substance in oxidative hair dye products · (a) (i) General use (a) (ii) Professional use · (a) To be printed on the label: The mixing ratio. “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary (b) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary “ black henna ” tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines (toluenediamines). Wear suitable gloves. For professional use only .
Source:GB Cosmetics Regulation, Annex III, entry 9a · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluene-3,4-Diamine and its salts, when used as a substance in hair dye products
CAS 496-72-0 · EC 207-826-2
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1313 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluidine sulphate (1:1)
CAS 540-25-0 · EC 208-741-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1070 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluidines, their isomers, salts and halogenated and sulphonated derivatives
CAS 26915-12-8 · EC 248-105-2
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 32 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toluidinium chloride
CAS 540-23-8 · EC 208-740-8
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1069 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Toxaphene
CAS 8001-35-2 · EC 232-283-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1105 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tralkoxydim (ISO); 2-(N-ethoxypropanimidoyl)-3-hydroxy-5-mesitylcyclohex-2-en-1-one
CAS 87820-88-0 · EC 618-075-9
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1570 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trans-4-cyclohexyl-L-proline monohydro-chloride
CAS 90657-55-9 · EC 419-160-1
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1117 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Transfluthrin (ISO); 2,3,5,6-tetrafluorobenzyl trans-2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylate
CAS 118712-89-3 · EC 405-060-5
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1737 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tranylcypromine (INN) and its salts
CAS 155-09-9 · EC 205-841-9
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 324 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tretamine (INN)
CAS 51-18-3 · EC 200-083-5
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 328 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tretinoin (INN) (retinoic acid and its salts)
CAS 302-79-4 · EC 206-129-0
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 375 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triadimenol (ISO); (1RS,2RS;1RS,2SR)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;α-tert-butyl-β-(4-chlorophenoxy)-1H-1,2,4-triazole-1-ethanol
CAS 55219-65-3 · EC 259-537-6
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1609 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy-3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate
CAS 221354-37-6 · EC 432-270-4
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1500 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triamterene (INN) and its salts
CAS 396-01-0 · EC 206-904-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 275 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tributyl phosphate
CAS 126-73-8 · EC 204-800-2
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1166 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trichlormethine (INN) and its salts
CAS 817-09-4 · EC 212-442-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 327 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trichloroacetic acid
CAS 76-03-9 · EC 200-927-2
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 10 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trichloroethylene
CAS 79-01-6 · EC 201-167-4
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 645 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trichloromethylstannane
CAS 993-16-8 · EC 213-608-8
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1554 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trichloronitromethane (chloropicrine)
CAS 76-06-2 · EC 200-930-9
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 325 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triclocarban
CAS 101-20-2 · EC 202-924-1
The consolidated GB Cosmetics Regulation lists this record in Annex V.
Conditions: 0,2% · Purity criteria: 3,3',4,4'-Tetrachloroazobenzene <1 ppm 3,3',4,4'-Tetrachloroazoxybenzene <1 ppm
Source:GB Cosmetics Regulation, Annex V, entry 23 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triclocarban
CAS 101-20-2 · EC 202-924-1
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: Rinse-off products · 1,5% · Purity criteria: 3,3',4,4'-Tetrachloroazobenzene ≤ 1 ppm 3,3',4,4'-Tetrachloroazoxybenzene ≤ 1 ppm For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product
Source:GB Cosmetics Regulation, Annex III, entry 100 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triclosan
CAS 3380-34-5 · EC 222-182-2
The consolidated GB Cosmetics Regulation lists this record in Annex V.
Conditions: (a) Toothpastes Hand soaps Body soaps/Shower gels Deodorants (non-spray) Face powders and blemish concealers Nail products for cleaning the fingernails and toenails before the application of artificial nail systems · (a) 0,3%
Source:GB Cosmetics Regulation, Annex V, entry 25 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Tridemorph
CAS 24602-86-6 · EC 246-347-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 737 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triflumizole (ISO); (1E)-N-[4-chloro-2-(trifluoromethyl)phenyl]-1- (1H-imidazol-1-yl)-2- propoxyethanimine
CAS 68694-11-1 · EC 604-708-8
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1640 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trifluoroiodomethane
CAS 2314-97-8 · EC 219-014-5
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1046 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trifluperidol (INN)
CAS 749-13-3
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 188 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trifluralin (ISO); α,α,α-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine; 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline;N,N-dipropyl-2,6-dinitro-4-trifluoromethylaniline
CAS 1582-09-8 · EC 216-428-8
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1498 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Triflusulfuron-methyl; methyl 2-({[4-(dimethylamino)-6-(2,2,2- trifluoroethoxy)-1,3,5-triazin-2- yl]carbamoyl}sulfamoyl)-3- methylbenzoate
CAS 126535-15-7 · EC 603-146-9
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1586 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trimanganese bis (orthophosphate)
The consolidated GB Cosmetics Regulation lists this record in Annex IV.
Source:GB Cosmetics Regulation, Annex IV, entry 141 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trimethyl borate
CAS 121-43-7 · EC 204-468-9
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1760 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trimethylbenzoyl diphenylphosphine oxide
CAS 75980-60-8 · EC 278-355-8
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Conditions: Artificial nail systems · 5,0% · Professional use · For professional use only Avoid skin contact Read directions for use carefully
Source:GB Cosmetics Regulation, Annex III, entry 311 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Trimethylopropane tri(3-aziridinylpropanoate); (TAZ)
CAS 52234-82-9 · EC 257-765-0
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Source:GB Cosmetics Regulation, Annex II, entry 1532 · version 2026-08-15 · effective Aug. 15, 2026 · source checked 2026-08-30
Market coverage contract
Complete consolidated annex dataset- Included scope
- Current consolidated Annexes II–VI for England, Scotland and Wales.
- If no match is found
- No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.
Complete verification checklist
- Confirm INCI/CAS/EC identity.
- Review every current GB Annex II–VI match.
- Check commencement dates and later statutory instruments.
- Verify SCPN, responsible-person, safety-report and labelling duties.
How Great Britain differs from other markets
Comparing this market's imported rules against every other market's for the same substance. A market with no imported rule for a substance is left out of that comparison rather than treated as permitting it.
A formula cleared elsewhere can fail here.
Permitted here under conditions and prohibited, or more tightly held, elsewhere — so a formula built for this market may not travel.
and 98 more — see the full comparison
Official sources and legal role
Great Britain Cosmetics Regulation — consolidated Annexes II–VI and amendments
Complete consolidated GB Annexes II–VI, with later amendments versioned separately
Legal meaning: Binding GB schedules and versioned amendments to retained Regulation 1223/2009; applies to England, Wales and Scotland, not Northern Ireland
Available language: English
Contains public sector information licensed under the Open Government Licence v3.0.
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: Office for Product Safety and Standards.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.