Canada cosmetic ingredient regulations

1,2-Epoxybutane

Canada Hotlist: 1,2-Epoxybutane

CAS 106-88-7

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 1 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1,3-Butadiene

Canada Hotlist: 1,3-Butadiene

CAS 106-99-0 · EC 203-450-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 2 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1,3-Dimethylpentylamine and its salts

Canada Hotlist: 1,3-Dimethylpentylamine and its salts

CAS 105-41-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 3 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1- and 2-Naphthylamines and their salts

Canada Hotlist: 1- and 2-Naphthylamines and their salts

CAS 134-32-7; 91-59-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 5 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1-Butyl-3-(N-crotonoylsulfanilyl) urea

Canada Hotlist: 1-Butyl-3-(N-crotonoylsulfanilyl) urea

CAS 52964-42-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2-Butenamide, N-[4-[[[(butylamino)carbonyl]amino]sulfonyl]phenyl]-; Crotonoylcarbutamide; Crotulin

Source:Hotlist prohibited entry 6 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1-Methoxy-2,4-diaminobenzene and its salts

Canada Hotlist: 1-Methoxy-2,4-diaminobenzene and its salts

CAS 615-05-4

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2,4-diaminoanisole; Cl 76050

Source:Hotlist prohibited entry 7 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1-Methoxy-2,5-diaminobenzene and their salts

Canada Hotlist: 1-Methoxy-2,5-diaminobenzene and their salts

CAS 5307-02-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2,5-diaminoanisole

Source:Hotlist prohibited entry 8 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

1-Naphthol, and its salts

Canada Hotlist: 1-Naphthol, and its salts

CAS 90-15-3 · EC 201-969-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) In Hair dyes as an oxidizing colouring agent | b) In combination with hydrogen peroxide · Maximum concentration: a) 2% | b) 1%

Source:Hotlist restricted entry 1 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

11-α-Hydroxypregn-4-ene-3,20-dione and its esters

Canada Hotlist: 11-α-Hydroxypregn-4-ene-3,20-dione and its esters

CAS 80-75-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 4 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2,3,7,8-Tetrachlorodibenzo-p-dioxin

Canada Hotlist: 2,3,7,8-Tetrachlorodibenzo-p-dioxin

CAS 1746-01-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 11 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2,3-Dichloro-2-methylbutane

Canada Hotlist: 2,3-Dichloro-2-methylbutane

CAS 507-45-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Amylene dichloride

Source:Hotlist prohibited entry 12 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2,4-Diaminophenylethanol and its salts

Canada Hotlist: 2,4-Diaminophenylethanol and its salts

CAS 14572-93-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 13 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2,4-Dihydroxy-3-methylbenzaldehyde

Canada Hotlist: 2,4-Dihydroxy-3-methylbenzaldehyde

CAS 6248-20-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 14 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-(4-Allyl-2-methoxyphenoxy)-N,N-diethylacetamide and its salts

Canada Hotlist: 2-(4-Allyl-2-methoxyphenoxy)-N,N-diethylacetamide and its salts

CAS 305-13-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Estil

Source:Hotlist prohibited entry 9 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-(4-Methoxybenzyl-N-(2-pyridyl)amino) ethyldimethylamine maleate

Canada Hotlist: 2-(4-Methoxybenzyl-N-(2-pyridyl)amino) ethyldimethylamine maleate

CAS 59-33-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 10 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Amino-1,2-bis(4-methoxyphenol) ethanol and its salts

Canada Hotlist: 2-Amino-1,2-bis(4-methoxyphenol) ethanol and its salts

CAS 5934-19-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 15 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Amino-4-nitrophenol

Canada Hotlist: 2-Amino-4-nitrophenol

CAS 99-57-0 · EC 202-767-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 16 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Amino-5-nitrophenol

Canada Hotlist: 2-Amino-5-nitrophenol

CAS 121-88-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 17 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Bromo-2-nitropropane-1,3-diol

Canada Hotlist: 2-Bromo-2-nitropropane-1,3-diol

CAS 52-51-7 · EC 200-143-0

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics that contain amines or amides. | b) Other cosmetics · Maximum concentration: b) 0.1%

Source:Hotlist restricted entry 2 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Methoxypropanol

Canada Hotlist: 2-Methoxypropanol

CAS 1589-47-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 18 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Methoxypropyl-1-acetate

Canada Hotlist: 2-Methoxypropyl-1-acetate

CAS 70657-70-4

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 19 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Methyl-m-phenylenediamine

Canada Hotlist: 2-Methyl-m-phenylenediamine

CAS 823-40-5 · EC 212-513-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Toluene-2,6-diamine

Source:Hotlist prohibited entry 21 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Methylheptylamine and its salts

Canada Hotlist: 2-Methylheptylamine and its salts

CAS 540-43-2

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2-Heptanamine, N-methyl-; Methylaminoheptane; Neosupranol; Oenethyl; Pacamine

Source:Hotlist prohibited entry 20 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Naphthol

Canada Hotlist: 2-Naphthol

CAS 135-19-3 · EC 205-182-7

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 22 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

2-Pentylidenecyclohexanone

Canada Hotlist: 2-Pentylidenecyclohexanone

CAS 25677-40-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 23 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

3,6,10-Trimethyl-3,5,9-undecatrien-2-one

Canada Hotlist: 3,6,10-Trimethyl-3,5,9-undecatrien-2-one

CAS 1117-41-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 25 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

3-(α-Naphthyl)-4-hydroxycoumarin

Canada Hotlist: 3-(α-Naphthyl)-4-hydroxycoumarin

CAS 39923-41-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 24 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

3-Diethylaminopropyl cinnamate

Canada Hotlist: 3-Diethylaminopropyl cinnamate

CAS 538-66-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 26 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

3-Imidazol-4-ylacrylic acid and its ethyl ester

Canada Hotlist: 3-Imidazol-4-ylacrylic acid and its ethyl ester

CAS 104-98-3; 27538-35-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Urocanic acid; ethyl urocanate

Source:Hotlist prohibited entry 27 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4,4'-Bis(dimethylamino)benzophenone

Canada Hotlist: 4,4'-Bis(dimethylamino)benzophenone

CAS 90-94-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Michler's ketone

Source:Hotlist prohibited entry 30 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin

Canada Hotlist: 4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 29 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4,4'-Isopropylidenediphenol

Canada Hotlist: 4,4'-Isopropylidenediphenol

CAS 80-05-7 · EC 201-245-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Bisphenol A

Source:Hotlist prohibited entry 31 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4,6-Dimethyl-8- tert -butylcoumarin

Canada Hotlist: 4,6-Dimethyl-8- tert -butylcoumarin

CAS 17874-34-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 32 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4- tert -Butylphenol

Canada Hotlist: 4- tert -Butylphenol

CAS 98-54-4

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 41 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4- tert -Butylpyrocatechol

Canada Hotlist: 4- tert -Butylpyrocatechol

CAS 98-29-3

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 42 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-(4-Methoxyphenyl)-3-butene-2-one

Canada Hotlist: 4-(4-Methoxyphenyl)-3-butene-2-one

CAS 943-88-4

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 28 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Amino-2-nitrophenol

Canada Hotlist: 4-Amino-2-nitrophenol

CAS 119-34-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 33 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Aminosalicylic acid and its salts

Canada Hotlist: 4-Aminosalicylic acid and its salts

CAS 65-49-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 34 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Benzyloxyphenol

Canada Hotlist: 4-Benzyloxyphenol

CAS 103-16-2

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Monobenzone

Source:Hotlist prohibited entry 35 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Ethoxy-m-phenylenediamine and its salts

Canada Hotlist: 4-Ethoxy-m-phenylenediamine and its salts

CAS 5862-77-1; 6219-69-8; 68015-98-5; 67801-06-3

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 36 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Ethoxyphenol

Canada Hotlist: 4-Ethoxyphenol

CAS 622-62-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 37 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Methoxy-m-phenylenediamine and its sulfate salts

Canada Hotlist: 4-Methoxy-m-phenylenediamine and its sulfate salts

CAS 615-05-4; 39156-41-7; 6219-67-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2,4-diaminoanisole; 2,4-diaminoanisole sulphate; 1,3-Benzenediamine, 4-methoxy-, sulfate

Source:Hotlist prohibited entry 38 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Methoxy-m-phenylenediamine-HCl

Canada Hotlist: 4-Methoxy-m-phenylenediamine-HCl

CAS 614-94-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 2,4-Diaminoanisole dihydrochloride

Source:Hotlist prohibited entry 39 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

4-Methyl-m-phenylenediamine and its salts

Canada Hotlist: 4-Methyl-m-phenylenediamine and its salts

CAS 95-80-7

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Toluene-2,4-diamine

Source:Hotlist prohibited entry 40 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5,5'-Diisopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite

Canada Hotlist: 5,5'-Diisopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite

CAS 552-22-7

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Thymol iodide

Source:Hotlist prohibited entry 44 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5,5-Diphenyl-4-imidazolidone

Canada Hotlist: 5,5-Diphenyl-4-imidazolidone

CAS 3254-93-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 45 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5- (α, β-Dibromophenethyl)-5-methylhydantoin

Canada Hotlist: 5- (α, β-Dibromophenethyl)-5-methylhydantoin

CAS 511-75-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 5-(1,2-Dibromo-2-phenylethyl)-5-methylimidazolidine-2,4-dione

Source:Hotlist prohibited entry 43 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5-Bromo-5-nitro-1,3-dioxane

Canada Hotlist: 5-Bromo-5-nitro-1,3-dioxane

CAS 30007-47-7 · EC 250-001-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics that contain amines or amides. | b) Other cosmetics · Maximum concentration: b) 0.1%

Source:Hotlist restricted entry 3 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

5-Methyl-2,3-hexanedione

Canada Hotlist: 5-Methyl-2,3-hexanedione

CAS 13706-86-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 46 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

6,10-Dimethyl-3,5,9-undecatrien-2-one

Canada Hotlist: 6,10-Dimethyl-3,5,9-undecatrien-2-one

CAS 141-10-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 47 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30