What does the restriction note for TOLUENE-2,6-DIAMINE mean?

The restriction field for TOLUENE-2,6-DIAMINE reads: II/413. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 823-40-5?

CAS 823-40-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains TOLUENE-2,6-DIAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5978131/07/2020

TOLUENE-2,6-DIAMINE

1,3-Benzenediamine, 2-methyl-

TOLUENE-2,6-DIAMINE is linked to 2 EU annex records on this page. Inventory note: II/413.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	2	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Evidence linked Prohibited Open this evidence	1	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	2	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 823-40-5

CAS 823-40-5PubChem CID 13205

2,6-Diaminotoluene

2,6-diaminotoluene is a diamine that is toluene in which both of the hydrogens ortho- to the methyl group are replaced by amino groups. It has a role as a mutagen. It is a diamine and a primary amino compound. It derives from a hydride of a toluene. — ChEBI

IUPAC name: 2-methylbenzene-1,3-diamine

Molecular formula: C7H10N2
Molecular weight: 122.17 g/mol
Exact mass: 122.084398327 Da
XLogP3: 0.9
Topological polar surface area: 52.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2,6-ToluenediamineToluene-2,6-diamine1,3-Benzenediamine, 2-methyl-2-Methyl-m-phenylenediamine2-Methyl-1,3-benzenediamine2,6-Tolylenediamine2,6-Toluylenediamine2,6-Diamino-1-methylbenzene

16 more reported names

2-Methyl-1,3-phenylenediamineo-Toluene diamineToluene, 2,6-diamino-1,3-DIAMINO-2-METHYLBENZENERODOL 26DATNSC-147490H838Q10551CHEBI:762882,6-DATRefChem:83124212-513-9EINECS 212-513-9NSC 147490CCRIS 3031HSDB 4131Tolylene-2,6-diamine

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:76288
ChEMBL:CHEMBL1489438
EPA DTXSID:DTXSID4027319
PubMed:23077796
PubMed:22319232
PubMed:22084566
PubMed:22016709
PubMed:21447151
PubMed:20869512
PubMed:20656055
PubMed:20026473
PubMed:18606566
PubMed:17728315
PubMed:17267016
PubMed:17070881

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TOLUENE-2,6-DIAMINE

INCI name

TOLUENE-2,6-DIAMINE

Description

1,3-Benzenediamine, 2-methyl-

Record provenance

Inventory reference: 59781
Imported identity: TOLUENE-2,6-DIAMINE
Source update: 31/07/2020

European Commission CosIng source notes

Annex records for TOLUENE-2,6-DIAMINE

Annex II Identified ingredient

Entry 1144

Diaminotoluene[1]; [4-methyl-m-phenylene diamine][2]; [2-methyl-m-phenylene diamine][3]

CAS: 25376-45-8 [1] / 95-80-7 [2] / 823-40-5 [3]

EC: 246-910-3 [1] / 202-453-1 [2] / 212-513-9 [3]

Annex II Restriction reference

Entry 413

2-Methyl-m-phenylenediamine (Toluene-2,6-diamine)

CAS: 823-40-5

EC: 212-513-9

Key data

CAS

823-40-5

212-513-9

Restriction

II/413

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28959 · TOLUENE-2,6-DIAMINE

Ingredients with overlapping formulation functions

TETRAHYDRO-6-NITROQUINOXALINEHAIR DYEING, LIGHT STABILIZER

THYMOLDENATURANT, FRAGRANCE, HAIR DYEING

TOLUENE-2,5-DIAMINEHAIR DYEING

TOLUENE-2,5-DIAMINE SULFATEHAIR DYEING

TOLUENE-3,4-DIAMINEHAIR DYEING

ULTRAMARINESHAIR DYEING

VITEX NEGUNDO FLOWER/LEAF/SEED OILANTI-SEBUM, ANTIOXIDANT, HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How TOLUENE-2,6-DIAMINE appears in the CosIng inventory

The CosIng inventory lists TOLUENE-2,6-DIAMINE as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TOLUENE-2,6-DIAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TOLUENE-2,6-DIAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for TOLUENE-2,6-DIAMINE reads: "II/413". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, TOLUENE-2,6-DIAMINE carries the following function designation(s):

HAIR DYEING

CAS 823-40-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for TOLUENE-2,6-DIAMINE

This page combines the CosIng inventory entry for TOLUENE-2,6-DIAMINE with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TOLUENE-2,6-DIAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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