Brazil cosmetic ingredient regulations
ANVISA materials require Portuguese-source verification and separate regulatory lists.
- Regulator
- ANVISA
- Source language
- Portuguese with INCI crosswalks
- Coverage version
- ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
What this list is
Brazil's list here is prohibitions only, published by ANVISA in Portuguese through numbered resolutions. The restricted-use and positive lists are separate instruments and are not part of this set.
- 1,387 Brazilian records, all of them prohibitions.
- ANVISA publishes through RDC resolutions, each amending what came before; the consolidated text is what governs.
- The Portuguese text is authoritative, with INCI names used as a crosswalk rather than as the legal identifier.
- Restricted substances, colourants, preservatives and UV filters live in other ANVISA instruments not covered here.
Every Brazilian record on this site is a prohibition, and that is a statement about the source rather than about Brazil. ANVISA regulates cosmetic ingredients through a series of resolutions — RDCs — each of which amends, extends or replaces earlier ones. The set we hold is the consolidated list of prohibited substances. Brazil's restricted-use list, and its positive lists for colourants, preservatives and UV filters, are separate instruments and are not represented below.
So a substance with no record here has not been checked against those other lists. Silence on this page means silence about prohibition, and nothing at all about restriction.
The Portuguese text is the legal one. INCI names appear as a crosswalk to help identify a substance across markets, but a Brazilian entry identifies its subject in Portuguese and by CAS number, and where a crosswalk and the source disagree, the source is what a regulator will read.
Checked against
Official ingredient records
1387 matching records3,3’-diclorobenzidina
CAS 91-94-1 · EC 202-109-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,3’-diclorobenzidina
Source:RDC 529/2021 consolidated annex, entry 712 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,3’-dimetoxibenzidina
CAS 119-90-4 · EC 204-355-4
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,3’-dimetoxibenzidina
Source:RDC 529/2021 consolidated annex, entry 709 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,4-dinitrotolueno
CAS 610-39-9 · EC 210-222-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,4-dinitrotolueno
Source:RDC 529/2021 consolidated annex, entry 693 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,4-metilenodioxianilina e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 14268-66-7 · EC 238-161-6
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,4-metilenodioxianilina e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1248 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,4-metilenodioxifenol e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 533-31-3 · EC 208-561-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,4-metilenodioxifenol e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1247 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,5,5-trimetilciclohex-2-enona
CAS 78-59-1 · EC 201-126-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,5,5-trimetilciclohex-2-enona
Source:RDC 529/2021 consolidated annex, entry 1101 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,5-dibromo-4-hidroxibenzonitrila
CAS 1689-84-5 · EC 216-882-7
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,5-dibromo-4-hidroxibenzonitrila
Source:RDC 529/2021 consolidated annex, entry 1031 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,5-dinitrotolueno
CAS 618-85-9 · EC 210-566-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,5-dinitrotolueno
Source:RDC 529/2021 consolidated annex, entry 694 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,6,10-Trimetil-3,5,9-undecatrieno-2-on a, quando usado como ingrediente de fragrância.
CAS 1117-41-5 · EC 214-245-8
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,6,10-Trimetil-3,5,9-undecatrieno-2-on a, quando usado como ingrediente de fragrância.
Source:RDC 529/2021 consolidated annex, entry 449 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,7-Dimetil-2-octeno-1-ol (6,7-dihidrogeraniol), quando usado como ingrediente de fragrância.
CAS 40607-48-5 · EC 254-999-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,7-Dimetil-2-octeno-1-ol (6,7-dihidrogeraniol), quando usado como ingrediente de fragrância.
Source:RDC 529/2021 consolidated annex, entry 429 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,7-bis(dietilamino)-fenoxazín-5-io e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 47367-75-9; 33203-82-6 · EC 251-403-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,7-bis(dietilamino)-fenoxazín-5-io e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1275 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,7-bis(dimetilamino)-fenotiazin-5-io e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 61-73-4 · EC 200-515-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,7-bis(dimetilamino)-fenotiazin-5-io e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1306 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3,7-diamino-2,8-dimetil-5-fenil-fenazinio e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 477-73-6 · EC 207-518-8
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3,7-diamino-2,8-dimetil-5-fenil-fenazinio e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1322 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-(4-isopropilfenil)-1,1-dimetiluréia
CAS 34123-59-6 · EC 251-835-4
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-(4-isopropilfenil)-1,1-dimetiluréia
Source:RDC 529/2021 consolidated annex, entry 1061 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-(N-metil-N-(4-metilamino-3-nitrofenil) amino) propano-1,2-diol e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 93633-79-5 · EC 403-440-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-(N-metil-N-(4-metilamino-3-nitrofenil) amino) propano-1,2-diol e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1289 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[(2,4-dimetil-5-sulfonatofenil)azo]-4-hi droxinaftaleno-1-sulfonato dissódico (CI 14700), quando usado como substância que entra na composição de corantes capilares
CAS 4548-53-2 · EC 224-909-9
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[(2,4-dimetil-5-sulfonatofenil)azo]-4-hi droxinaftaleno-1-sulfonato dissódico (CI 14700), quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1341 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[(2-nitro-4-(trifluorometil)fenil)amino] propano-1,2-diol (HC Amarelo nº 6) e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 104333-00-8 · EC 410-010-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[(2-nitro-4-(trifluorometil)fenil)amino] propano-1,2-diol (HC Amarelo nº 6) e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1324 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[[4-[(2-hidroxietil)amino]-2-nitrofenil]a mino]-1,2-propanodiol e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 114087-41-1; 114087-42-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[[4-[(2-hidroxietil)amino]-2-nitrofenil]a mino]-1,2-propanodiol e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1327 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[[4-[(2-hidroxietil)metilamino]-2-nitrof enil]amino]-1,2-propanodiol e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 173994-75-7; 102767-27-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[[4-[(2-hidroxietil)metilamino]-2-nitrof enil]amino]-1,2-propanodiol e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1326 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[[4-[[diamino(fenilazo)fenil]azo]-1-naft alenil]azo]-N,N,N-trimetil-benzenaminio e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 83803-98-9 · EC 280-919-3
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[[4-[[diamino(fenilazo)fenil]azo]-1-naft alenil]azo]-N,N,N-trimetil-benzenaminio e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1298 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-[[4-[[diamino(fenillazo)fenil]azo]-2-me tilfenil]azo]-N,N,N-trimetil-benzenamini o e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 83803-99-0 · EC 280-920-9
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-[[4-[[diamino(fenillazo)fenil]azo]-2-me tilfenil]azo]-N,N,N-trimetil-benzenamini o e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1297 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-etil-2-metil-2-(3-metilbutil)-1,3-oxazoli dina
CAS 143860-04-2 · EC 421-150-7
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-etil-2-metil-2-(3-metilbutil)-1,3-oxazoli dina
Source:RDC 529/2021 consolidated annex, entry 1163 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-hidroxi-4-(4’-sulfonatonaftilazo)naftale no-2,7-disulfonato trissódico (CI 16185),
CAS 915-67-3 · EC 213-022-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-hidroxi-4-(4’-sulfonatonaftilazo)naftale no-2,7-disulfonato trissódico (CI 16185),
Source:RDC 529/2021 consolidated annex, entry 1350 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-hidroxi-4-[(1-sulfonato-2-naftil)azo]-2- naftoato de cálcio (CI 15880), quando usado como substância que entra na composição de corantes capilares
CAS 6417-83-0 · EC 229-142-3
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-hidroxi-4-[(1-sulfonato-2-naftil)azo]-2- naftoato de cálcio (CI 15880), quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1349 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-hidroxi-N-(o-tolil)-4-[(2,4,5- triclorofenil)azo]naftaleno-2-carboxamid a (CI 12370) e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 6535-46-2 · EC 229-440-3
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-hidroxi-N-(o-tolil)-4-[(2,4,5- triclorofenil)azo]naftaleno-2-carboxamid a (CI 12370) e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1346 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-nitro-4-aminofenoxietanol e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 50982-74-6
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-nitro-4-aminofenoxietanol e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1250 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3-Óxido de
CAS 38304-91-5 · EC 253-874-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3-Óxido de
Source:RDC 529/2021 consolidated annex, entry 372 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3´6´-dihidroxi-4´,5´-diiodoespirol[isobenz enofurano-1(3H),9´-[9H]xanteno]-3-ona (Solvente Vermelho 73) e seu respectivo sal sódico (Vermelho Ácido 95;CI 45425), quando usado como substância que entra na composição de corantes capilares
CAS 38577-97-8; 33239-19-9 · EC 254-010-7; 251-419-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3´6´-dihidroxi-4´,5´-diiodoespirol[isobenz enofurano-1(3H),9´-[9H]xanteno]-3-ona (Solvente Vermelho 73) e seu respectivo sal sódico (Vermelho Ácido 95;CI 45425), quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1336 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
3’-etil-5’,6’,7’,8’-tetrahidro-5’,5’,8’,8’- tetrametil-2’-acetonaftona ou 7- acetil-6-etil -1,1,4,4-tetrametil - 1,2,3,4-tetrahidronaftaleno
CAS 88-29-9 · EC 201-817-7
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 3’-etil-5’,6’,7’,8’-tetrahidro-5’,5’,8’,8’- tetrametil-2’-acetonaftona ou 7- acetil-6-etil -1,1,4,4-tetrametil - 1,2,3,4-tetrahidronaftaleno
Source:RDC 529/2021 consolidated annex, entry 362 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 - Metil – m - fenilenodiamina e seus sais
CAS 95-80-7 · EC 202-453-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 - Metil – m - fenilenodiamina e seus sais
Source:RDC 529/2021 consolidated annex, entry 364 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 - terc – butilfenol
CAS 98-54-4 · EC 202-679-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 - terc – butilfenol
Source:RDC 529/2021 consolidated annex, entry 340 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 - terc – butilpirocatecol
CAS 98-29-3 · EC 202-653-9
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 - terc – butilpirocatecol
Source:RDC 529/2021 consolidated annex, entry 341 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 – Benziloxifenol, 4 - metoxifenol e 4 – etoxifeno; 4-etoxifenol (4-ETHOXYPHENOL)
CAS 103-16-2; 150-76-5; 622-62-8 · EC 203-083-3; 205-769-8; 210-748-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 – Benziloxifenol, 4 - metoxifenol e 4 – etoxifeno; 4-etoxifenol (4-ETHOXYPHENOL)
Source:RDC 529/2021 consolidated annex, entry 178 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 – Fenilbut - 3 - en - 2 – ona
CAS 122-57-6 · EC 204-555-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 – Fenilbut - 3 - en - 2 – ona
Source:RDC 529/2021 consolidated annex, entry 356 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4 – dimetilaminobenzoato de amila, misturas de isômeros (padimato A*)
CAS 14779-78-3 · EC 238-849-6
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4 – dimetilaminobenzoato de amila, misturas de isômeros (padimato A*)
Source:RDC 529/2021 consolidated annex, entry 381 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4',5'-dibromo-3',6'-dihidroxiespiro[isobe nzofurano-1(3H),9'-[9H]xanteno]-3-ona; 4',5'-dibromofluoresceina (Solvente Vermelho 72) e seu sal sódico (CI 45370), quando usado como substância que entra na composição de corantes capilares
CAS 596-03-2; 4372-02-5 · EC 209-876-0; 224-468-2
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4',5'-dibromo-3',6'-dihidroxiespiro[isobe nzofurano-1(3H),9'-[9H]xanteno]-3-ona; 4',5'-dibromofluoresceina (Solvente Vermelho 72) e seu sal sódico (CI 45370), quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1333 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4, 4' - Dihidroxi - 3, 3' - (3 - metiltiopropilideno) dicumarina
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4, 4' - Dihidroxi - 3, 3' - (3 - metiltiopropilideno) dicumarina
Source:RDC 529/2021 consolidated annex, entry 207 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4'-[(4-metil-1,3-fenileno)bis(azo)]bis[6- metil-1,3-benzenodiamina] (Marrom Básico 4) e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 4482-25-1 · EC 224-764-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4'-[(4-metil-1,3-fenileno)bis(azo)]bis[6- metil-1,3-benzenodiamina] (Marrom Básico 4) e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1296 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4'-bis(dimetilamino)benzofenona
CAS 90-94-8 · EC 202-027-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4'-bis(dimetilamino)benzofenona
Source:RDC 529/2021 consolidated annex, entry 1149 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4'-diaminodifenilamina e seus sais, quando usado como substância que entra na composição de corantes capilares
CAS 537-65-5 · EC 208-673-4
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4'-diaminodifenilamina e seus sais, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1309 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4'-oxidianilina (éter p-aminofenílico) e seus sais
CAS 101-80-4 · EC 202-977-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4'-oxidianilina (éter p-aminofenílico) e seus sais
Source:RDC 529/2021 consolidated annex, entry 1160 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4'-tiodianilina e seus sais
CAS 139-65-1 · EC 205-370-9
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4'-tiodianilina e seus sais
Source:RDC 529/2021 consolidated annex, entry 1159 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4’-Metilenodianilina
CAS 101-77-9 · EC 202-974-4
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4’-Metilenodianilina
Source:RDC 529/2021 consolidated annex, entry 705 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4’-bi-o-toluidina
CAS 119-93-7 · EC 204-358-0
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4’-bi-o-toluidina
Source:RDC 529/2021 consolidated annex, entry 721 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4’-metilenodi-o-toluidina
CAS 838-88-0 · EC 212-658-8
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4’-metilenodi-o-toluidina
Source:RDC 529/2021 consolidated annex, entry 707 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4′-carbonimidoilbis[N,N-dimetilanilina]
CAS 492-80-8 · EC 207-762-5
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4′-carbonimidoilbis[N,N-dimetilanilina]
Source:RDC 529/2021 consolidated annex, entry 1067 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4′-isobutiletilidenodifenol
CAS 6807-17-6 · EC 401-720-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4′-isobutiletilidenodifenol
Source:RDC 529/2021 consolidated annex, entry 1079 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,4′-metilenobis(2-etilanilina)
CAS 19900-65-3 · EC 243-420-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,4′-metilenobis(2-etilanilina)
Source:RDC 529/2021 consolidated annex, entry 1038 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,5-diamino-1-((4-clorofenil)metil)-1H-pi razol, quando usado como substância que entra na composição de corantes capilares
CAS 163183-00-4
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,5-diamino-1-((4-clorofenil)metil)-1H-pi razol, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1218 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
4,5-diamino-1-metilpirazole, e seu sal HCl, quando usado como substância que entra na composição de corantes capilares
CAS 20055-01-0; 21616-59-1
ANVISA lists this substance among materials that may not be used in personal-hygiene products, cosmetics or perfumes in Brazil.
Conditions: 4,5-diamino-1-metilpirazole, e seu sal HCl, quando usado como substância que entra na composição de corantes capilares
Source:RDC 529/2021 consolidated annex, entry 1217 (through RDC 1.030/2026) · version RDC 529/2021 consolidated through RDC 1.030/2026 · effective June 15, 2026 · source checked 2026-08-31
Market coverage contract
Complete prohibited dataset plus current restricted-list workflow- Included scope
- All 1,387 substantive current prohibited rows in RDC 529/2021 consolidated through RDC 1.030/2026, plus the current RDC 1.029 restricted-list and identity workflow.
- If no match is found
- RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
Complete verification checklist
- Resolve Portuguese, INCI and CAS identity with the ANVISA crosswalk.
- Check the consolidated prohibited list including RDC 1.030/2026 changes.
- Apply RDC 1.029/2026 restrictions and the still-effective complementary rules.
- Verify Mercosur incorporation, regularisation, labelling and transition periods.
How Brazil differs from other markets
Comparing this market's imported rules against every other market's for the same substance. A market with no imported rule for a substance is left out of that comparison rather than treated as permitting it.
A formula cleared elsewhere can fail here.
Official sources and legal role
Brazil ANVISA INCI translation panel
Official Portuguese–INCI–CAS crosswalk and status history; not a complete allowed list
Legal meaning: Identity and labelling crosswalk only; regulatory lists must be sourced separately
Available language: Portuguese with INCI and CAS
Brazil ANVISA restricted substances — RDC 1.029/2026
First part of the current restricted-substances list with use fields, maximum concentrations, limitations and label warnings
Legal meaning: Binding ANVISA resolution effective on publication; replaced RDC 530/2021 for this list part
Available language: Portuguese with INCI and CAS fields
Brazil ANVISA consolidated prohibited substances — RDC 529/2021 through RDC 1.030/2026
All 1,387 substantive current prohibited rows after applying RDC 1.030/2026 additions, amendments and exclusions to RDC 529/2021
Legal meaning: Binding consolidated prohibited list for personal-hygiene products, cosmetics and perfumes
Available language: Portuguese with English/INCI names and CAS/EC fields
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: ANVISA.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: Portuguese with INCI crosswalks.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.