What does the restriction note for BASIC RED 2 mean?

The restriction field for BASIC RED 2 reads: II/1322. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 477-73-6?

CAS 477-73-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains BASIC RED 2?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3207715/10/2010

BASIC RED 2

3,7-diamino-2,8-dimethyl-5-phenylphenazinium chloride (CI 50240)

BASIC RED 2 is linked to 1 EU annex record on this page. Inventory note: II/1322.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 477-73-6

CAS 477-73-6PubChem CID 2723800

C.I. Basic Red 2

Safranin O is an organic chloride salt having 3,7-diamino-2,8-dimethyl-5-phenylphenazin-5-ium as the counterion. It is commonly used for staining Gram negative bacteria. It has a role as a fluorochrome and a histological dye. It contains a 3,7-diamino-2,8-dimethyl-5-phenylphenazin-5-ium. — ChEBI

IUPAC name: 3,7-dimethyl-10-phenylphenazin-10-ium-2,8-diamine chloride

Molecular formula: C20H19ClN4
Molecular weight: 350.8 g/mol
Exact mass: 350.1298243 Da
Topological polar surface area: 68.8 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 2
Defined stereocentres: 0

Also known as

BASIC RED 2SafraninSafranine OSafranine TSafranin TGossypimineSafranine ZhSafranine A

16 more reported names

Safranine THSafranineSafranine BSafranine GSafranine JSafranine YSafranine GFSafranine OKSafranine TNSafranine TSSafranine YNTolusafranineHidaco safranineMitsui safranineBrilliant safranine GCalcozine Red Y

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:197447
ChEMBL:CHEMBL5195997
EPA DTXSID:DTXSID60874047
PubMed:11408205

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BASIC RED 2

INCI name

BASIC RED 2

Description

3,7-diamino-2,8-dimethyl-5-phenylphenazinium chloride (CI 50240)

Record provenance

Inventory reference: 32077
Imported identity: BASIC RED 2
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for BASIC RED 2

Annex II Restriction reference

Entry 1322

Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl- and its salts, when used as a substance in hair dye…

CAS: 477-73-6

EC: 207-518-8

Key data

CAS

477-73-6

207-518-8

Restriction

II/1322

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3092 · BASIC RED 2

Ingredients with overlapping formulation functions

BASIC ORANGE 69HAIR DYEING

BASIC RED 1HAIR DYEING

BASIC RED 118HAIR DYEING

BASIC RED 1:1HAIR DYEING

BASIC RED 22HAIR DYEING

BASIC RED 46HAIR DYEING

BASIC RED 51HAIR DYEING

BASIC RED 76HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BASIC RED 2 appears in the CosIng inventory

The CosIng inventory lists BASIC RED 2 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BASIC RED 2 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BASIC RED 2 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for BASIC RED 2 reads: "II/1322". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, BASIC RED 2 carries the following function designation(s):

HAIR DYEING

CAS 477-73-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for BASIC RED 2

This page combines the CosIng inventory entry for BASIC RED 2 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research BASIC RED 2 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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