MINOXIDIL
2,4-Pyrimidinediamine, 6-(1-Piperidinyl)-, 3-Oxide
MINOXIDIL is linked to 1 EU annex record on this page. Inventory note: II/372.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Evidence linked Prohibited Open this evidence | 1 | English |
| Canada | Evidence linked Prohibited Open this evidence | 1 | English and French |
| New Zealand | Evidence linked Prohibited Open this evidence | 1 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Evidence linked Prohibited Open this evidence | 1 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Evidence linked Prohibited Open this evidence | 1 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Evidence linked Prohibited Open this evidence | 1 | Portuguese with INCI crosswalks |
| India | Evidence linked Prohibited Open this evidence | 1 | English and Hindi |
| Saudi Arabia | Evidence linked Prohibited Open this evidence | 1 | Arabic and English |
Chemical identity and properties

Minoxidil
Minoxidil is a pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6. It has a role as a vasodilator agent and an antihypertensive agent. It is a member of piperidines, an aminopyrimidine and a pyrimidine N-oxide. — ChEBI
- IUPAC name
- 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
- Molecular formula
- C9H15N5O
- Molecular weight
- 209.25 g/mol
- Exact mass
- 209.12766012 Da
- XLogP3
- 1.2
- Topological polar surface area
- 88.9 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:6942
- ChEBI:CHEBI:92128
- ChEMBL:CHEMBL1372483
- ChEMBL:CHEMBL609587
- ChEMBL:CHEMBL802
- EPA DTXSID:DTXSID301372970
- EPA DTXSID:DTXSID9040685
- PubMed:29968805
- PubMed:22363845
- PubMed:22077158
- PubMed:17761356
- PubMed:16253450
- PubMed:16043173
- PubMed:15922339
- PubMed:4647
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for MINOXIDIL
INCI name
MINOXIDIL
INN name
minoxidil
Description
2,4-Pyrimidinediamine, 6-(1-Piperidinyl)-, 3-Oxide
Record provenance
- Inventory reference
- 85161
- Imported identity
- MINOXIDIL
- Source update
- 15/10/2010
Annex records for MINOXIDIL
6-(Piperidinyl)-2,4-pyrimidinediamine-3-oxide (Minoxidil (INN)) and its salts
Key data
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
- HAIR FIXING
- Permitting physical control of hair style.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How MINOXIDIL appears in the CosIng inventory
The CosIng inventory lists MINOXIDIL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
MINOXIDIL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for MINOXIDIL
This page combines the CosIng inventory entry for MINOXIDIL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research MINOXIDIL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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