What does the restriction note for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL mean?

The restriction field for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL reads: II/1307. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 94082-85-6?

CAS 94082-85-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3152115/10/2010

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL

Ethanol, 2,2'-[(4,6-diamino-1,3-phenylene)bis(oxy)]bis-, dihydrochloride

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL is linked to 1 EU annex record on this page. Inventory note: II/1307.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 94082-85-6

CAS 94082-85-6PubChem CID 17909858

4,6-Bis(2-hydroxyethoxy)-m-phenylenediamine hydrochloride

IUPAC name: 2-[2,4-diamino-5-(2-hydroxyethoxy)phenoxy]ethanol;dihydrochloride

Molecular formula: C10H18Cl2N2O4
Molecular weight: 301.16 g/mol
Exact mass: 300.0643624 Da
Topological polar surface area: 111.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 6
Covalent units: 3
Defined stereocentres: 0

Also known as

UNII-59949U2SPDEthanol, 2,2'-((4,6-diamino-1,3-phenylene)bis(oxy))bis-, dihydrochloride4,6-Bis(2-hydroxyethoxy)-m-phenylenediamine HCl [INCI]Ethanol, 2,2'-[(4,6-diamino-1,3-phenylene)bis(oxy)]bis-, dihydrochloride4,6-BIS(2-HYDROXYETHOXY)-m-PHENYLENEDIAMINE HCl4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE DIHYDROCHLORIDERefChem:96598WFSSVTHTFFJDKO-UHFFFAOYSA-N

2 more reported names

2,2'-((4,6-Diamino-1,3-phenylene)bis(oxy))bis(ethan-1-ol) dihydrochloride2,2'-[(4,6-Diamino-1,3-phenylene)bis(oxy)]di(ethan-1-ol)--hydrogen chloride (1/2)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID20240380

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL

INCI name

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL

Description

Ethanol, 2,2'-[(4,6-diamino-1,3-phenylene)bis(oxy)]bis-, dihydrochloride

Record provenance

Inventory reference: 31521
Imported identity: 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL

Annex II Restriction reference

Entry 1307

4,6-Bis(2-hydroxyethoxy)-m-phenylenediamine and its salts, when used as a substance in hair dye pro…

CAS: 94082-85-6

Key data

CAS

94082-85-6

—

Restriction

II/1307

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#310 · 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCl

Ingredients with overlapping formulation functions

4,4'-DIAMINODIPHENYLAMINE SULFATEHAIR DYEING

4,5-DIAMINO-1-((4-CHLOROPHENYL)METHYL)-1H-PYRAZOLE-SULFATEHAIR DYEING

4,5-DIAMINO-1-METHYLPYRAZOLE HCLHAIR DYEING

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINEHAIR DYEING

4-AMINO-2-HYDROXYTOLUENEHAIR DYEING

4-AMINO-2-HYDROXYTOLUENE SULFATEHAIR DYEING

4-AMINO-2-NITRODIPHENYLAMINE-2'-CARBOXYLIC ACIDHAIR DYEING

4-AMINO-2-NITROPHENOLHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL appears in the CosIng inventory

The CosIng inventory lists 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL reads: "II/1307". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL carries the following function designation(s):

HAIR DYEING

CAS 94082-85-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL

This page combines the CosIng inventory entry for 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research 4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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