ASEAN cosmetic ingredient regulations

2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate;

CAS 15625-89-5 · EC 239-701-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1721 · version 2026-1 · source checked 2026-08-30

2-methoxyethyl acrylate

CAS 3121-61-7 · EC 221-499-3 (I)

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1668 · version 2026-1 · source checked 2026-08-30

2-methylimidazole

CAS 693-98-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1654 · version 2026-1 · source checked 2026-08-30

2-{4-(2-Ammoniopropylamino)-6-[4-hydroxy-3-(5-methyl-2-

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1194 · version 2026-1 · source checked 2026-08-30

3',6'-Dihydroxy-4',5'-diiodospiro(isobenzofuran-1(3H),9'-

CAS 38577-97-8; 33239-19-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1336 · version 2026-1 · source checked 2026-08-30

3'-Ethyl-5',6',7’,8'-tetrahydro-5',5',8',8'-tetramethyl-2'-

CAS 88-29-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 362 · version 2026-1 · source checked 2026-08-30

3(or 5)-((4-(Benzylmethylamino)phenyl)azo)-1,2-(or 1,4)-

CAS 89959-98-8; 12221-69-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1259 · version 2026-1 · source checked 2026-08-30

3(or5)-[[4-[(7-amino-1-hydroxy-3-sulphonato-2-naphthyl)azo]-1-

CAS 3442-21-5; 34977-63-4 · EC 222-351-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1266 · version 2026-1 · source checked 2026-08-30

3,3'-Dibromo-4,4'-hexamethylenedioxydi- benzamidine (Dibromohexamidine) and its salts ( including isethionate) (CAS No. 93856-83-8)

CAS 93856-83-8 · EC 299-116-4

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.1%

Source:ASEAN Annex VI, reference 15 · version 2026-1 · source checked 2026-08-30

3,3'-Dichlorobenzidine

CAS 91-94-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 712 · version 2026-1 · source checked 2026-08-30

3,3'-Dichlorobenzidine dihydrochloride

CAS 612-83-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 715 · version 2026-1 · source checked 2026-08-30

3,3'-Dichlorobenzidine dihydrogen bis(sulphate)

CAS 64969-34-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 718 · version 2026-1 · source checked 2026-08-30

3,3'-Dichlorobenzidine sulphate

CAS 74332-73-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 719 · version 2026-1 · source checked 2026-08-30

3,3'-Dimethoxybenzidine

CAS 119-90-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 709 · version 2026-1 · source checked 2026-08-30

3,3- Bis(4-hydroxyphenyl)phthalide (Phenolphthalein) (INN)

CAS 77-09-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 417 · version 2026-1 · source checked 2026-08-30

3,3-(1,4-Phenylene) bis (5,6-diphenyl- 1,2,4-triazine) CAS No. 55514-22-2

CAS 55514-22-2 · EC 700-823-1 (L)

ASEAN Annex VII lists this record among UV filters allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 5% · Not to be used in application that may lead to exposure of the end user's lungs by inhalation.’

Source:ASEAN Annex VII, reference 30 · version 2026-1 · source checked 2026-08-30

3,3’-(1,4-Phenylenedimethylene)bis(7,7-dimethyl-2- oxo-bicyclo-[2,2,1]hept-1-yl methanesulfonic acid) and its salts Terephthalylidene CAS No. 92761-26-7 Dicamphor Sulfonic Acid CAS No. 90457-82-2

CAS 92761-26-7; 90457-82-2

ASEAN Annex VII lists this record among UV filters allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 10% (expressed as acid)

Source:ASEAN Annex VII, reference 7 · version 2026-1 · source checked 2026-08-30

3,3’-(Sulfonylbis(2-nitro-4,1-phenylene)imino)bis(6-

CAS 6373-79-1 · EC 228-922-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1258 · version 2026-1 · source checked 2026-08-30

3,3’-Bis(1-hydroxymethyl-2,5-dioxoimidazolidin- 4-yl)-1,1’-methylenediurea (“Imidazolidinyl urea”) CAS No. 39236-46-9

CAS 39236-46-9 · EC 254-372-6

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.6%

Source:ASEAN Annex VI, reference 27 · version 2026-1 · source checked 2026-08-30

3,4',5–Tribromosalicylanilide

CAS 87-10-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 373 · version 2026-1 · source checked 2026-08-30

3,4,5-Trimethoxyphenethylamine and its salts

CAS 54-04-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 222 · version 2026-1 · source checked 2026-08-30

3,4-Diaminobenzoic acid, when used as a substance in hair dye

CAS 619-05-6 · EC 210-577-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1229 · version 2026-1 · source checked 2026-08-30

3,4-Dihydro-2-methoxy-2-methyl-4-phenyl-2H,5H,pyrano(3,2-c)-

CAS 518-20-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 234 · version 2026-1 · source checked 2026-08-30

3,4-Dihydro-2H-1,4-benzoxazin-6-ol Hydroxybenzomorpholine CAS No 26021-57-8

CAS 26021-57-8 · EC 247-415-5

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 % • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg(21) • Keep in nitrite-free containers The direction for use “wear suitable gloves” must be included in label or leaflet text. · The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 234 · version 2026-1 · source checked 2026-08-30

3,4-Dinitrotoluene

CAS 610-39-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 693 · version 2026-1 · source checked 2026-08-30

3,4-Methylenedioxyaniline and its salts, when used as a

CAS 14268-66-7 · EC 238-161-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1248 · version 2026-1 · source checked 2026-08-30

3,4-Methylenedioxyphenol and its salts, when used as a

CAS 533-31-3 · EC 208-561-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1247 · version 2026-1 · source checked 2026-08-30

3,5,5-Trimethylcyclohex-2-enone

CAS 78-59-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1101 · version 2026-1 · source checked 2026-08-30

3,5-Dibromo-4-hydroxybenzonitrile

CAS 1689-84-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1031 · version 2026-1 · source checked 2026-08-30

3,5-Dinitrotoluene

CAS 618-85-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 694 · version 2026-1 · source checked 2026-08-30

3,6,10-Trimethyl-3,5,9-undecatrien-2-one, when used as a

CAS 1117-41-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 449 · version 2026-1 · source checked 2026-08-30

3,7-Dimethyl-2-octen-1-ol (6,7-Dihydrogeraniol), when used as a

CAS 40607-48-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 429 · version 2026-1 · source checked 2026-08-30

3,7-Dimethylocta-2,6- dienenitrile

CAS 5146-66-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1638 · version 2026-1 · source checked 2026-08-30

3- and 4-(4-Hydroxy-4-methylpentyl) cyclohex-3-ene-1- carbaldehyde (HICC)

CAS 51414-25-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1380 · version 2026-1 · source checked 2026-08-30

3-(1–Naphthyl)-4-hydroxycoumarin

CAS 39923-41-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 243 · version 2026-1 · source checked 2026-08-30

3-(2-Hydroxyethyl)-p- phenylene diammonium sulphate Hydroxyethyl-p- Phenylenediamine Sulfate CAS No 93841-25-9

CAS 93841-25-9 · EC 298-995-1

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0% (calculated as sulphate) Indonesia only: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% (calculated as sulphate). The direction for use “wear suitable gloves” must be included in label or leaflet text. · The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows Indonesia only: Rinse immediately if product comes into contact with eyes.

Source:ASEAN Annex III, reference 256 · version 2026-1 · source checked 2026-08-30

3-(4-Chlorophenyl)-1,1-dimethyluronium trichloroacetate;

CAS 140-41-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1019 · version 2026-1 · source checked 2026-08-30

3-(4-Isopropylphenyl)-1,1-dimethylurea

CAS 34123-59-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1061 · version 2026-1 · source checked 2026-08-30

3-(N-Hexadecyl-N-2- hydroxyethyl ammonio) propylbis (2-hydroxyethyl) ammonium difluoride

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Oral hygiene products (except mouthwash) (b) Mouthwash · 0.15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15 % · (a) & (b) Contains 3-(N-Hexadecyl-N-2- hydroxyethylammonio) propylbis (2- hydroxyethyl) ammonium difluoride (a) “Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimize swallowing. In case of intake of fluoride from other sources consult a dentist or doctor.” (12) (b) Do not use for children below 6 years of age

Source:ASEAN Annex III, reference 37 · version 2026-1 · source checked 2026-08-30

3-(N-Methyl-N-(4-methylamino-3-nitrophenyl)amino)propane-1,2-

CAS 93633-79-5 · EC 403-440-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1289 · version 2026-1 · source checked 2026-08-30

3-(Piperazin-1-yl)-benzo[d]isothiazole hydrochloride

CAS 87691-88-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1513 · version 2026-1 · source checked 2026-08-30

3-(difluoromethyl)-1- methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)

CAS 907204-31-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1672 · version 2026-1 · source checked 2026-08-30

3-(p-Chlorophenoxy)-propane-1,2-diol (chlorphenesin) CAS No. 104-29-0

CAS 104-29-0 · EC 203-192-6

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.3%

Source:ASEAN Annex VI, reference 50 · version 2026-1 · source checked 2026-08-30

3-Acetyl-6-methylpyran-2,4 (3H)-dione (Dehydroacetic acid) and its salts Dehydroacetic acid (CAS No. 520-45-6, 16807- 48-0), Sodium dehydroacetate (CAS No. 4418-26-2)

CAS 520-45-6; 16807-48-0; 4418-26-2 · EC 224-580-1

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.6% (acid) · Prohibited in aerosol dispensers (sprays)

Source:ASEAN Annex VI, reference 13 · version 2026-1 · source checked 2026-08-30

3-Amino-2,4-dichlorophenol and its hydrochloride 3-Amino-2,4-dichlorophenol 3-Amino-2,4-dichlorophenol HCl CAS No 61693-42-3 / CAS No 61693- 43-4

CAS 61693-42-3; 61693-43-4 · EC 262-909-0

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 1.5% (as hydrochloride) · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5 % (as hydrochloride) (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows

Source:ASEAN Annex III, reference 227 · version 2026-1 · source checked 2026-08-30

3-Amino-7-(dimethylamino)-2- methoxyphenoxazin-5-ium chloride Basic Blue 124 CAS No 67846-56-4

CAS 67846-56-4

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · 0.5% · — Do not use with nitrosating agents — Maximum nitrosamine content: 50 μg/kg(21) — Keep in nitrite-free containers The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Do not use to dye eyelashes or eyebrows.”

Source:ASEAN Annex III, reference 321 · version 2026-1 · source checked 2026-08-30

3-Amino-9-ethyl carbazole; 9-ethylcarbazol-3-ylamine

CAS 132-32-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1523 · version 2026-1 · source checked 2026-08-30

3-Benzylidene camphor (3-Benzylidene Camphor)

CAS 15087-24-8 · EC 239-139-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1379 · version 2026-1 · source checked 2026-08-30

3-Chloro-2,6-Dihydroxy-4-methyl-benzaldehyde (chloroatranol)

CAS 57074-21-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1382 · version 2026-1 · source checked 2026-08-30

3-Chloro-4-(3-fluorobenzyloxy)aniline

CAS 202197-26-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1520 · version 2026-1 · source checked 2026-08-30