ASEAN cosmetic ingredient regulations

4-Benzyloxyphenol and 4-ethoxyphenol

CAS 103-16-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 178 · version 2026-1 · source checked 2026-08-30

4-Chloro-2-aminophenol, when used as a substance in hair dye

CAS 95-85-2 · EC 202-458-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1219 · version 2026-1 · source checked 2026-08-30

4-Cyano-2,6-diiodophenyl octanoate

CAS 3861-47-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1063 · version 2026-1 · source checked 2026-08-30

4-Diethylamino-o-toluidine and its salts, when used as a substance in hair dye products

CAS 148-71-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1310 · version 2026-1 · source checked 2026-08-30

4-Ethoxy-m-phenylenediamine and its salts

CAS 67801-06-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 406 · version 2026-1 · source checked 2026-08-30

4-Ethylamino-3-nitrobenzoic acid (N-Ethyl-3-Nitro PABA) and its

CAS 2788-74-1 · EC 412-090-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1290 · version 2026-1 · source checked 2026-08-30

4-Hydroxyindole, when used as a substance in hair dye

CAS 2380-94-1 · EC 219-177-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1220 · version 2026-1 · source checked 2026-08-30

4-Mesyl-2-nitrotoluene

CAS 1671-49-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1499 · version 2026-1 · source checked 2026-08-30

4-Methoxytoluene-2,5-diamine and its HCl salt, when used as a

CAS 56496-88-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1221 · version 2026-1 · source checked 2026-08-30

4-Methyl-m-phenylene diisocyanate

CAS 584-84-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1119 · version 2026-1 · source checked 2026-08-30

4-Methyl-m-phenylenediamine and its salts

CAS 95-80-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 364 · version 2026-1 · source checked 2026-08-30

4-Methylbenzylidene Camphor; 3-(4'-methylbenzylidene)-camphor

CAS 36861-47-9; 38102-62-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1723 · version 2026-1 · source checked 2026-08-30

4-Nitro-m-phenylenediamine and its salts, when used as a

CAS 5131-58-8 · EC 225-876-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1282 · version 2026-1 · source checked 2026-08-30

4-Nitrobiphenyl

CAS 92-93-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 686 · version 2026-1 · source checked 2026-08-30

4-Nitrosophenol

CAS 104-91-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 995 · version 2026-1 · source checked 2026-08-30

4-Phenylazophenylene-1,3-diamine citrate hydrochloride

CAS 5909-04-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 81 · version 2026-1 · source checked 2026-08-30

4-Phenylbut-3-en-2-one

CAS 122-57-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 356 · version 2026-1 · source checked 2026-08-30

4-Vinylcyclohexene

CAS 100-40-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1569 · version 2026-1 · source checked 2026-08-30

4-[(3-Chlorophenyl)(1H-imidazol-1-yl)methyl]-1,2-

CAS 159939-85-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1516 · version 2026-1 · source checked 2026-08-30

4-[(4-Aminophenyl)(4-iminocyclohexa-2,5-dien-1-

CAS 3248-93-9; 632-99-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1329 · version 2026-1 · source checked 2026-08-30

4-[(4-Ethoxyphenyl)azo]naphthol (Solvent Red 3; CI 12010) and

CAS 6535-42-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1344 · version 2026-1 · source checked 2026-08-30

4-[(4-Nitrophenyl)azo]aniline (Disperse Orange 3) and its salts,

CAS 730-40-5 · EC 211-984-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1281 · version 2026-1 · source checked 2026-08-30

4-[(tetrahydro-2H-pyran-2-yl)oxy]phenol (Deoxyarbutin,

CAS 53936-56-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1657 · version 2026-1 · source checked 2026-08-30

4-[4-(1,3-Dihydroxyprop-2-yl)phenylamino]-1,8-dihydroxy-5-

CAS 114565-66-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1002 · version 2026-1 · source checked 2026-08-30

4-methylpentan-2-one; isobutyl methyl ketone (MIBK)

CAS 08-10-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1689 · version 2026-1 · source checked 2026-08-30

4-o-Tolylazo-o-toluidine

CAS 97-56-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 989 · version 2026-1 · source checked 2026-08-30

4-tert-Butyl-3-methoxy-2,6-dinitrotoluene (Musk ambrette)

CAS 83-66-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 414 · version 2026-1 · source checked 2026-08-30

4-tert-Butylbenzoic acid

CAS 98-73-7 · EC 202-696-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1549 · version 2026-1 · source checked 2026-08-30

4-tert-Butylphenol

CAS 98-54-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 340 · version 2026-1 · source checked 2026-08-30

4-tert-Butylpyrocatechol

CAS 98-29-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 341 · version 2026-1 · source checked 2026-08-30

5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19;

CAS 1047-16-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1366 · version 2026-1 · source checked 2026-08-30

5,5'-Di-isopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodate

CAS 552-22-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 361 · version 2026-1 · source checked 2026-08-30

5,5-Diphenyl-4-imidazolidone

CAS 3254-93-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 160 · version 2026-1 · source checked 2026-08-30

5,6,12,13-Tetrachloroanthra(2,1,9-def:6,5,10-

CAS 115662-06-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1003 · version 2026-1 · source checked 2026-08-30

5-((4-(Dimethylamino)phenyl)azo)-1,4-dimethyl-1H-1,2,4-

CAS 12221-52-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1292 · version 2026-1 · source checked 2026-08-30

5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-

CAS 41107-56-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1064 · version 2026-1 · source checked 2026-08-30

5-(3-Butyryl-2,4,6-trimethylphenyl)-2-[1-(ethoxyimino)propyl]-3-

CAS 138164-12-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1190 · version 2026-1 · source checked 2026-08-30

5-(alpha, beta-Dibromophenethyl)-5-methylhydantoin

CAS 511-75-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 119 · version 2026-1 · source checked 2026-08-30

5-Amino-2,6-dimethoxy-3-hydroxypyridine and its salts, when

CAS 104333-03-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1308 · version 2026-1 · source checked 2026-08-30

5-Amino-4-fluoro-2-methylphenol sulfate, when used as a

CAS 163183-01-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1222 · version 2026-1 · source checked 2026-08-30

5-Chloro-1,3-dihydro-2H-indol-2-one

CAS 17630-75-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1034 · version 2026-1 · source checked 2026-08-30

5-Ethoxy-3-trichloromethyl-1,2,4-thiadiazole

CAS 2593-15-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1054 · version 2026-1 · source checked 2026-08-30

5-Hydroxy-1,4-benzodioxane and its salts, when used as a

CAS 10288-36-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1246 · version 2026-1 · source checked 2026-08-30

5-Methyl-2,3-hexanedione, when used as a fragrance ingredient.

CAS 13706-86-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 447 · version 2026-1 · source checked 2026-08-30

5-Nitro-o-toluidine [1] 5-Nitro-o-toluidine hydrochloride [2]

CAS 99-55-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1195 · version 2026-1 · source checked 2026-08-30

5-Nitroacenaphthene

CAS 602-87-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 691 · version 2026-1 · source checked 2026-08-30

5-fluoro-1,3-dimethyl-N-[2-(4- methylpentan-2-yl) phenyl]-1H-

CAS 494793-67-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1674 · version 2026-1 · source checked 2026-08-30

5-tert-Butyl-1,2,3-trimethyl-4,6-dinitrobenzene (Musk tibetene)

CAS 145-39-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 422 · version 2026-1 · source checked 2026-08-30

6,10-Dimethyl-3,5,9-undecatrien-2-one, when used as a

CAS 141-10-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 433 · version 2026-1 · source checked 2026-08-30

6,6'-Bis(diazo-5,5',6,6'-tetrahydro-5,5'-dioxo)[methylene-bis(5-

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1497 · version 2026-1 · source checked 2026-08-30