What does the restriction note for BASIC RED 22 mean?

The restriction field for BASIC RED 22 reads: II/1292. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 12221-52-2?

CAS 12221-52-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains BASIC RED 22?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3207815/10/2010

BASIC RED 22

5-(4'-dimethylaminophenylazo)-1,4-dimethyl-triazolium chloride

BASIC RED 22 is linked to 1 EU annex record on this page. Inventory note: II/1292.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 12221-52-2

CAS 12221-52-2PubChem CID 73759884

Basic Red 22

IUPAC name: 4-[(2,4-dimethyl-1,2,4-triazol-4-ium-3-yl)diazenyl]-N,N-dimethylaniline;methyl sulfate

Molecular formula: C13H20N6O4S
Molecular weight: 356.40 g/mol
Exact mass: 356.12667431 Da
Topological polar surface area: 124.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 8
Covalent units: 2
Defined stereocentres: 0

Also known as

Synacril Red 3BC.I. Basic Red 22Czerwien anilanowa blnCzerwien anilanowa bln [Polish]7W576V407RBASIC RED 22 METHOSULFATE1H-1,2,4-Triazolium, 5-((4-(dimethylamino)phenyl)azo)-1,4-dimethyl-, methyl sulfate4H-1,2,4-Triazolium, 5-((p-(dimethylamino)phenyl)azo)-1,4-dimethyl-, methyl sulfate

14 more reported names

4H-1,2,4-Triazolium, 5-(2-(4-(dimethylamino)phenyl)diazenyl)-1,4-dimethyl-, methyl sulfate (1:1)CI 11055C.I. 110555-((4-(Dimethylamino)phenyl)azo)-1,4-dimethyl-1H-1,2,4-triazolium1H-1,2,4-Triazolium, 5-((4-(dimethylamino)phenyl)azo)-1,4-dimethyl-1H-1,2,4-Triazolium, 5-[[4-(dimethylamino)phenyl]azo]-1,4-dimethyl-, methyl sulfate4H-1,2,4-Triazolium, 5-[2-[4-(dimethylamino)phenyl]diazenyl]-1,4-dimethyl-, methyl sulfate (1:1)CI Basic Red 22RefChem:561091BASIC RED 22 [INCI]602-140-3UNII-7W576V407RZRVPOURSNDQODC-UHFFFAOYSA-M4-[(2,4-Dimethyl-2,4-dihydro-3H-1,2,4-triazol-3-ylidene)hydrazinylidene]-N,N-dimethylcyclohexa-2,5-dien-1-iminium methyl sulfate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID10946021

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match73759884

Attributed physical-property, hazard, environmental and use annotations.

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BASIC RED 22

INCI name

BASIC RED 22

Description

5-(4'-dimethylaminophenylazo)-1,4-dimethyl-triazolium chloride

Record provenance

Inventory reference: 32078
Imported identity: BASIC RED 22
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for BASIC RED 22

Annex II Restriction reference

Entry 1292

5-((4-(Dimethylamino)phenyl)azo)-1,4-dimethyl-1H-1,2,4-triazolium and its salts, when used as a sub…

CAS: 12221-52-2

Key data

CAS

12221-52-2

—

Restriction

II/1292

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3093 · BASIC RED 22

Ingredients with overlapping formulation functions

BASIC RED 1HAIR DYEING

BASIC RED 118HAIR DYEING

BASIC RED 1:1HAIR DYEING

BASIC RED 2HAIR DYEING

BASIC RED 46HAIR DYEING

BASIC RED 51HAIR DYEING

BASIC RED 76HAIR DYEING

BASIC VIOLET 1HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BASIC RED 22 appears in the CosIng inventory

The CosIng inventory lists BASIC RED 22 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BASIC RED 22 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BASIC RED 22 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for BASIC RED 22 reads: "II/1292". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, BASIC RED 22 carries the following function designation(s):

HAIR DYEING

CAS 12221-52-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for BASIC RED 22

This page combines the CosIng inventory entry for BASIC RED 22 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research BASIC RED 22 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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