What does the restriction note for BASIC RED 46 mean?

The restriction field for BASIC RED 46 reads: II/1259. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 12221-69-1?

CAS 12221-69-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains BASIC RED 46?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3207915/10/2010

BASIC RED 46

1H-1,2,4-triazolium, 1,4-dimethyl-5-[[4-[methyl(phenylmethyl)amino]phenyl]azo]-, bromide

BASIC RED 46 is linked to 1 EU annex record on this page. Inventory note: II/1259.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 12221-69-1

CAS 12221-69-1PubChem CID 12011963

Basic Red 46

IUPAC name: N-benzyl-4-[(2,4-dimethyl-1,2,4-triazol-4-ium-3-yl)diazenyl]-N-methylaniline bromide

Molecular formula: C18H21BrN6
Molecular weight: 401.3 g/mol
Exact mass: 400.10111 Da
Topological polar surface area: 49.7 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 5
Covalent units: 2
Defined stereocentres: 0

Also known as

C.I. Basic Red 4658KJM7T349LOWACRYL RED 46C.I.BASIC RED 46C.I.1108254H-1,2,4-TRIAZOLIUM, 1,4-DIMETHYL-5-(2-(4-(METHYL(PHENYLMETHYL)AMINO)PHENYL)DIAZENYL)-, BROMIDE (1:1)astrazone red FBLRefChem:116622

15 more reported names

602-156-0BASICRED46Basic Red 46, Technical grade5-((4-(Benzyl(methyl)amino)phenyl)diazenyl)-1,4-dimethyl-4H-1,2,4-triazol-1-ium bromideN-benzyl-4-[(2,4-dimethyl-1,2,4-triazol-4-ium-3-yl)diazenyl]-N-methylaniline;bromideUNII-58KJM7T349DIACRYL RED GRL-NC18H21BrN6SYHRPJPCZWZVSR-UHFFFAOYSA-MHY-D1214AS-17150CS-01436005-({4-[Benzyl(methyl)amino]phenyl}diazenyl)-1,4-dimethyl-1H-1,2,4-triazol-4-ium bromideN-benzyl-4-[(2,4-dimethyl-1,2,4-triazol-4-ium-3-yl)azo]-N-methyl-aniline;bromide1H-1,2,4-Triazolium, 1,4-dimethyl-5-[(E)-2-[4-[methyl(phenylmethyl)amino]phenyl]diazenyl]-, bromide (1:1)

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID30879822

Evidence from additional scientific databases

NIH PubChem PUG-View

Exact identifier match12011963

Attributed physical-property, hazard, environmental and use annotations.

Signal: Danger Source: European Chemicals Agency (ECHA)
GHS Hazard Statements: H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]; H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H411 (50%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]; H412 (50%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
Precautionary Statement Codes: P264, P264+P265, P270, P273, P280, P301+P317, P305+P354+P338, P317, P330, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
ECHA C&L Notifications Summary: Aggregated GHS information provided per 6 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status

Source	Result	Checked
NIH PubChem PUG-View	Exact match	2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BASIC RED 46

INCI name

BASIC RED 46

Description

1H-1,2,4-triazolium, 1,4-dimethyl-5-[[4-[methyl(phenylmethyl)amino]phenyl]azo]-, bromide

Record provenance

Inventory reference: 32079
Imported identity: BASIC RED 46
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for BASIC RED 46

Annex II Restriction reference

Entry 1259

3(or5)-((4-(Benzylmethylamino)phenyl)azo)-1,2-(or1,4)-dimethyl-1H-1,2,4-triazolium and its salts, w…

CAS: 89959-98-8 / 12221-69-1

EC: 289-660-0

Key data

CAS

12221-69-1

—

Restriction

II/1259

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3094 · BASIC RED 46

Ingredients with overlapping formulation functions

BASIC RED 118HAIR DYEING

BASIC RED 1:1HAIR DYEING

BASIC RED 2HAIR DYEING

BASIC RED 22HAIR DYEING

BASIC RED 51HAIR DYEING

BASIC RED 76HAIR DYEING

BASIC VIOLET 1HAIR DYEING

BASIC VIOLET 11:1HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BASIC RED 46 appears in the CosIng inventory

The CosIng inventory lists BASIC RED 46 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BASIC RED 46 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BASIC RED 46 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for BASIC RED 46 reads: "II/1259". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, BASIC RED 46 carries the following function designation(s):

HAIR DYEING

CAS 12221-69-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for BASIC RED 46

This page combines the CosIng inventory entry for BASIC RED 46 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research BASIC RED 46 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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