What does the restriction note for PHENOLPHTHALEIN mean?

The restriction field for PHENOLPHTHALEIN reads: II/417. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains PHENOLPHTHALEIN?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8499715/10/2010

PHENOLPHTHALEIN

PHENOLPHTHALEIN is linked to 1 EU annex record on this page. Inventory note: II/417.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Evidence linked Prohibited Open this evidence	1	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 5768-87-6

CAS 5768-87-6PubChem CID 2735117

2-((4-Hydroxyphenyl)(4-oxo-2,5-cyclohexadien-1-ylidene)methyl)benzoic acid

IUPAC name: 2-[(4-hydroxyphenyl)-(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzoic acid

Molecular formula: C20H14O4
Molecular weight: 318.3 g/mol
Exact mass: 318.08920892 Da
XLogP3: 3.8
Topological polar surface area: 74.6 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Benzoic acid, 2-((4-hydroxyphenyl)(4-oxo-2,5-cyclohexadien-1-ylidene)methyl)-2-((4-hydroxyphenyl)(4-oxocyclohexa-2,5-dienylidene)methyl)benzoic acid2-[(4-hydroxyphenyl)(4-oxo-2,5-cyclohexadien-1-ylidene)methyl]benzoic acid2-[(4-hydroxyphenyl)(4-oxocyclohexa-2,5-dienylidene)methyl]benzoic acidAG-205/33124005SR-01000117802SR-01000117802-12-[(4-HYDROXYPHENYL)(4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE)METHYL]BENZOIC ACID

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL222562
EPA DTXSID:DTXSID10973276

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 77-09-8

CAS 77-09-8PubChem CID 4764

Phenolphthalein

Phenolphthalein is a member of phenols. It is functionally related to a 2-benzofuran-1(3H)-one. — ChEBI

IUPAC name: 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one

Molecular formula: C20H14O4
Molecular weight: 318.3 g/mol
Exact mass: 318.08920892 Da
XLogP3: 3.6
Topological polar surface area: 66.8 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

PhthalimettenEuchessinaPhenolaxPhthalinEspotabsPurgophenKoprolLaxogen

16 more reported names

TrilaxPurgaSpulmako-laxChocolaxPurgenDihydroxyphthalophenonePhenolphtaleineCorrectolMedilaxColaxLaxin3,3-Bis(4-hydroxyphenyl)phthalideFemiLax3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranoneFenolftaleinFenolftaleina

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:34914
ChEMBL:CHEMBL63857
EPA DTXSID:DTXSID0021125
PubMed:23041872
PubMed:23037998
PubMed:23001288
PubMed:22975400
PubMed:22902504
PubMed:22862562
PubMed:22784191
PubMed:22675455
PubMed:22645489
PubMed:22629096
PubMed:22615669
PubMed:22559521

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PHENOLPHTHALEIN

INCI name

PHENOLPHTHALEIN

Record provenance

Inventory reference: 84997
Imported identity: PHENOLPHTHALEIN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PHENOLPHTHALEIN

Annex II Restriction reference

Entry 417

3,3-Bis(4-hydroxyphenyl)phthalide (Phenolphthalein (INN))

CAS: 77-09-8

EC: 201-004-7

Key data

CAS

77-09-8 / 5768-87-6

201-004-7

Restriction

II/417

Function

NOT REPORTED: No function currently reported.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#20705 · PHENOLPHTHALEIN

Ingredients with overlapping formulation functions

PERFLUORO DIMETHYLETHYLPENTANENOT REPORTED

PERFLUOROPROPANENOT REPORTED

PERFLUOROPROPYLENENOT REPORTED

PHALAENOPSIS APHRODITE EMBRYO EXTRACTNOT REPORTED

PHOSPHORUSNOT REPORTED

PHTHALIC ANHYDRIDENOT REPORTED

PHYLLOSTACHYS PUBESCENS BARK EXTRACTNOT REPORTED

PHYTELEPHAS AEQUATORIALIS SEED POWDERNOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PHENOLPHTHALEIN appears in the CosIng inventory

The CosIng inventory lists PHENOLPHTHALEIN as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PHENOLPHTHALEIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PHENOLPHTHALEIN appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for PHENOLPHTHALEIN reads: "II/417". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, PHENOLPHTHALEIN carries the following function designation(s):

NOT REPORTED

CAS 77-09-8 / 5768-87-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for PHENOLPHTHALEIN

This page combines the CosIng inventory entry for PHENOLPHTHALEIN with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research PHENOLPHTHALEIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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