European Union cosmetic ingredient regulations
EU Cosmetics Regulation 1223/2009 annexes and the CosIng discovery database.
- Regulator
- European Commission
- Source language
- English and EU languages
- Coverage version
- Regulation (EC) 1223/2009 consolidated to 1 May 2026
What this list is
The EU list is not one list. Regulation 1223/2009 splits substances across five annexes that answer different questions, and reading the wrong one is the most common way to get an EU answer wrong.
- Annex II prohibits 1,739 substances outright.
- Annex III permits 373 substances only within stated limits, product types and warnings.
- Annexes IV, V and VI are positive lists: 154 colourants, 54 preservatives, 33 UV filters.
- For those three categories, absence from the annex means not permitted — the opposite of Annex II's logic.
- CosIng is a discovery database, not the law; the annexes as published are.
Most markets on this site publish one list. The EU publishes five, and they do not work the same way. Annex II names substances that may not be used at all. Annex III names substances that may be used, but only within a concentration limit, for stated product types, and often with a warning that must appear on the label. Annexes IV, V and VI are positive lists for colourants, preservatives and UV filters.
That last distinction reverses the logic and catches people out. For a substance in general, absence from Annex II is not permission — nothing has been decided about it. For a preservative, absence from Annex V is a decision: it may not be used as a preservative in a cosmetic product. The same silence means opposite things depending on which annex you are reading.
CosIng is worth naming separately, because it is what most searches land on. It is the Commission's database for finding ingredients and their annex references, and it is genuinely useful for that. It is not the legal text. When CosIng and the published annex disagree — usually because an amendment has come into force and the database has not caught up — the annex governs.
An Annex III entry is also more than a number. The limit, the product-type condition and the warning text travel together, and quoting the concentration without the condition it applies to produces an answer that is right about the figure and wrong about the product.
Checked against
Official ingredient records
2353 matching recordsN-methoxy-N-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide; pydiflumetofen
Source reference: Annex II, entry 1687 · 11/11/2022
N-{2-[[1,1'-bi(cyclopropyl)]-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide; sedaxane
Source reference: Annex II, entry 1688 · 11/11/2022
4-methylpentan-2-one; isobutyl methyl ketone (MIBK)
Source reference: Annex II, entry 1689 · 11/11/2022
Caramiphen (INN) and its salts
Source reference: Annex II, entry 169 · 20/10/2010
Dimethomorph (ISO); (E,Z)-4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl)morpholine
Source reference: Annex II, entry 1690 · 11/11/2022
Imazamox (ISO); (RS)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methoxymethylnicotinic acid
Source reference: Annex II, entry 1691 · 11/11/2022
Thiamethoxam (ISO); 3-(2-chloro-thiazol-5-ylmethyl)-5-methyl[1,3,5]oxadiazinan-4-ylidene-N-nitroamine
Source reference: Annex II, entry 1692 · 11/11/2022
Triticonazole (ISO); (RS)-(E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-methyl)cyclopentanol
Source reference: Annex II, entry 1693 · 11/11/2022
Desmedipham (ISO); ethyl 3-phenylcarbamoyloxyphenylcarbamate
Source reference: Annex II, entry 1694 · 11/11/2022
Dibutyltin bis(2-ethylhexanoate)
Source reference: Annex II, entry 1696 · 24/08/2023
Dibutyltin di(acetate)
Source reference: Annex II, entry 1697 · 24/08/2023
Barium diboron tetraoxide
Source reference: Annex II, entry 1699 · 24/08/2023
Diethyl 4-nitrophenyl phosphate (Paraoxon - ISO)
Source reference: Annex II, entry 170 · 20/10/2010
2,2-dimethylpropan-1-ol,tribromo derivative; 3-bromo-2,2-bis(bromomethyl)propan-1-ol
Source reference: Annex II, entry 1700 · 24/08/2023
2,4,6-tri-tert-butylphenol
Source reference: Annex II, entry 1701 · 24/08/2023
4,4’-sulphonyldiphenol; bisphenol S
Source reference: Annex II, entry 1702 · 24/08/2023
Quinoclamine (ISO); 2-amino-3-chloro-1,4-naphthoquinone
Source reference: Annex II, entry 1704 · 24/08/2023
Perfluoroheptanoic acid; tridecafluoroheptanoic acid
Source reference: Annex II, entry 1705 · 24/08/2023
methyl N-(isopropoxycarbonyl)-L-valyl-(3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate
Source reference: Annex II, entry 1706 · 24/08/2023
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts
Source reference: Annex II, entry 1707 · 24/08/2023
6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
Source reference: Annex II, entry 1708 · 24/08/2023
6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
Source reference: Annex II, entry 1709 · 24/08/2023
Metethoheptazine (INN) and its salts
Source reference: Annex II, entry 171 · 20/10/2010
Theophylline; 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Source reference: Annex II, entry 1710 · 24/08/2023
1,3,5-triazine-2,4,6-triamine; melamine
Source reference: Annex II, entry 1711 · 24/08/2023
Fluopicolide (ISO); 2,6-dichloro-N-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide
Source reference: Annex II, entry 1712 · 24/08/2023
N-(2-nitrophenyl)phosphoric triamide
Source reference: Annex II, entry 1713 · 24/08/2023
N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; isoflucypram
Source reference: Annex II, entry 1714 · 24/08/2023
Reaction mass of 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide [≥ 78 % syn isomers ≤ 15 % anti isomers relative content]; isopyrazam
Source reference: Annex II, entry 1715 · 24/08/2023
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents]
Source reference: Annex II, entry 1716 · 24/08/2023
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate;
Source reference: Annex II, entry 1718 · 25/09/2023
Pentapotassium 2,2’,2’’,2’’’,2’’’’-(ethane-1,2-diylnitrilo)pentaacetate
Source reference: Annex II, entry 1719 · 24/08/2023
Oxpheneridine (INN) and its salts
Source reference: Annex II, entry 172 · 20/10/2010
N-carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid); Pentetic Acid (INCI)
Source reference: Annex II, entry 1720 · 24/08/2023
Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate; Pentasodium Pentetate (INCI)
Source reference: Annex II, entry 1721 · 24/08/2023
Acetamiprid (ISO); (1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine
Source reference: Annex II, entry 1722 · 24/08/2023
Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene
Source reference: Annex II, entry 1723 · 24/08/2023
Bentazone (ISO); 3-isopropyl-2,1,3-benzothiadiazine-4-one-2,2-dioxide
Source reference: Annex II, entry 1724 · 24/08/2023
Styrene/Acrylates copolymer (nano) [INCI] Sodium Styrene/Acrylates copolymer (nano) [INCI]
Source reference: Annex II, entry 1725 · 18/03/2024
Copper (nano) [INCI] Colloidal Copper (nano) [INCI]
Source reference: Annex II, entry 1726 · 04/06/2024
Silver (nano) [1 nm < particle diameter ≤ 100 nm] Silver (massive) [particle diameter ≥ 1 mm]
Source reference: Annex II, entry 1727 · 15/01/2026
Gold (nano) [INCI], Colloidal Gold (nano) [INCI] [1] Gold Thioethylamino Hyaluronic Acid (nano) [INCI] [2] Acetyl heptapeptide-9 Colloidal gold (nano) [INCI] [3]
Source reference: Annex II, entry 1728 · 04/06/2024
Platinum (nano) [INCI], Colloidal Platinum (nano) [INCI] [1] Acetyl tetrapeptide-17 Colloidal Platinum (nano) [INCI] [2]
Source reference: Annex II, entry 1729 · 04/06/2024
Ethoheptazine (INN) and its salts
Source reference: Annex II, entry 173 · 20/10/2010
Market coverage contract
Complete annex dataset- Included scope
- Annexes II–VI: prohibited and restricted substances, colourants, preservatives and UV filters.
- If no match is found
- No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Complete verification checklist
- Confirm the exact INCI/CAS/EC identity.
- Review every matching Annex II–VI row and its conditions.
- Check SCCS opinions, CMR/nanomaterial rules and later amendments.
- Verify product classification, claims, labelling and responsible-person duties.
How European Union differs from other markets
Comparing this market's imported rules against every other market's for the same substance. A market with no imported rule for a substance is left out of that comparison rather than treated as permitting it.
A formula cleared elsewhere can fail here.
and 22 more — see the full comparison
Permitted here under conditions and prohibited, or more tightly held, elsewhere — so a formula built for this market may not travel.
and 103 more — see the full comparison
Official sources and legal role
PubChem PUG-View annotations
Attributed physical-property, hazard, environmental, use and literature annotations for uniquely matched PubChem compounds
Legal meaning: Scientific context aggregated by PubChem; individual values retain their named depositor or publication source
EMBL-EBI ChEBI 2.0
Curated definitions, chemical classes, roles, names, relationships and cross-references
Legal meaning: Curated scientific ontology; not a cosmetics permission or prohibition list
FDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Legal meaning: Identity registry only; UNII availability does not imply FDA review or approval
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Legal meaning: Independent expert review considered by FDA; not a government approval or binding market rule
EU Safety Gate cosmetic product alerts
Published cosmetic product alerts, notifying country, risk, product identifiers and corrective measures
Legal meaning: Official market-surveillance alerts; not proof that a named ingredient caused an incident
Available language: English and EU languages
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: European Commission.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English and EU languages.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.