European Union cosmetic ingredient regulations
EU Cosmetics Regulation 1223/2009 annexes and the CosIng discovery database.
- Regulator
- European Commission
- Source language
- English and EU languages
- Coverage version
- Regulation (EC) 1223/2009 consolidated to 1 May 2026
What this list is
The EU list is not one list. Regulation 1223/2009 splits substances across five annexes that answer different questions, and reading the wrong one is the most common way to get an EU answer wrong.
- Annex II prohibits 1,739 substances outright.
- Annex III permits 373 substances only within stated limits, product types and warnings.
- Annexes IV, V and VI are positive lists: 154 colourants, 54 preservatives, 33 UV filters.
- For those three categories, absence from the annex means not permitted — the opposite of Annex II's logic.
- CosIng is a discovery database, not the law; the annexes as published are.
Most markets on this site publish one list. The EU publishes five, and they do not work the same way. Annex II names substances that may not be used at all. Annex III names substances that may be used, but only within a concentration limit, for stated product types, and often with a warning that must appear on the label. Annexes IV, V and VI are positive lists for colourants, preservatives and UV filters.
That last distinction reverses the logic and catches people out. For a substance in general, absence from Annex II is not permission — nothing has been decided about it. For a preservative, absence from Annex V is a decision: it may not be used as a preservative in a cosmetic product. The same silence means opposite things depending on which annex you are reading.
CosIng is worth naming separately, because it is what most searches land on. It is the Commission's database for finding ingredients and their annex references, and it is genuinely useful for that. It is not the legal text. When CosIng and the published annex disagree — usually because an amendment has come into force and the database has not caught up — the annex governs.
An Annex III entry is also more than a number. The limit, the product-type condition and the warning text travel together, and quoting the concentration without the condition it applies to produces an answer that is right about the figure and wrong about the product.
Checked against
Official ingredient records
2353 matching recordsNickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]
Source reference: Annex II, entry 1461 · 30/07/2020
Nickel boride (NiB) [1]; Dinickel boride [2]; Trinickel boride [3]; Nickel boride [4]; Dinickel silicide [5]; Nickel disilicide [6];Dinickel phosphide [7]; Nickel boron phosphide [8]
Source reference: Annex II, entry 1462 · 04/08/2020
Dialuminium nickel tetraoxide [1]; Nickel titanium trioxide [2]; Nickel titanium oxide [3]; Nickel divanadium hexaoxide [4]; Cobalt dimolybdenum nickel octaoxide [5]; Nickel zirkonium trioxide [6]; Molybdenum nickel tetraoxide [7]; Nickel tungsten tetraoxide [8]; Olivine, nickel green [9]; Lithium nickel dioxide [10]; Molybdenum nickel oxide [11]
Source reference: Annex II, entry 1463 · 04/08/2020
Cobalt lithium nickel oxide
Source reference: Annex II, entry 1464 · 30/07/2020
Dibutyltin dichloride; (DBTC)
Source reference: Annex II, entry 1466 · 30/07/2020
4,4'-Bis(N-carbamoyl-4-methylbenzenesulfonamide)diphenylmethane
Source reference: Annex II, entry 1467 · 30/07/2020
1,2-Epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide
Source reference: Annex II, entry 1469 · 30/07/2020
Metformin (INN) and its salts
Source reference: Annex II, entry 147 · 20/10/2010
6-Glycidyloxynapht-1-yl oxymethyloxirane
Source reference: Annex II, entry 1470 · 30/07/2020
2-(2-Aminoethylamino)ethanol; (AEEA)
Source reference: Annex II, entry 1471 · 30/07/2020
2,3-Epoxypropyltrimethylammonium chloride; glycidyl trimethylammonium chloride
Source reference: Annex II, entry 1473 · 30/07/2020
1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride
Source reference: Annex II, entry 1474 · 30/07/2020
(E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
Source reference: Annex II, entry 1475 · 30/07/2020
4,4'-(1,3-Phenylene-bis(1-methylethylidene))bis-phenol
Source reference: Annex II, entry 1476 · 30/07/2020
2-Chloro-6-fluoro-phenol
Source reference: Annex II, entry 1477 · 30/07/2020
2-Methyl-5-tert-butylthiophenol
Source reference: Annex II, entry 1478 · 30/07/2020
2-Butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
Source reference: Annex II, entry 1479 · 30/07/2020
Isosorbide dinitrate (INN)
Source reference: Annex II, entry 148 · 20/10/2010
Profoxydim (ISO); 2-{(EZ)-1-[(2RS)-2-(4-chlorophenoxy)propoxyimino]butyl}-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-one
Source reference: Annex II, entry 1480 · 30/07/2020
Tepraloxydim (ISO); (RS)-(EZ)-2-{1-[(2E)-3-chloroallyloxyimino]propyl}-3-hydroxy-5-perhydropyran-4-ylcyclohex-2-en-1-one
Source reference: Annex II, entry 1481 · 30/07/2020
Cyclic 3-(1,2-ethanediylacetale)-estra-5(10),9(11)-diene-3,17-dione
Source reference: Annex II, entry 1482 · 30/07/2020
Androsta-1,4,9(11)-triene-3,17-dione
Source reference: Annex II, entry 1483 · 30/07/2020
Reaction mass of: Ca salicylates (branched C10-14 and C18-30 alkylated); Ca phenates (branched C10-14 and C18-30 alkylated); Ca sulfurised phenates (branched C10-14 and C18-30 alkylated)
Source reference: Annex II, entry 1484 · 30/07/2020
1,2-Benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich
Source reference: Annex II, entry 1485 · 30/07/2020
Reaction mass of: diester of 4,4'-methylenebis[2-(2-hydroxy-5-methylbenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulfonic acid (1:2); triester of 4,4'-methylenebis[2-(2-hydroxy-5-methylbenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxonaphthalene-1-sulfonic acid (1:3)
Source reference: Annex II, entry 1486 · 30/07/2020
Diammonium 1-hydroxy-2-(4-(4-carboxyphenylazo)-2,5-dimethoxyphenylazo)-7-amino-3-naphthalenesulfonate
Source reference: Annex II, entry 1487 · 30/07/2020
3-Oxoandrost-4-ene-17-ß-carboxylic acid
Source reference: Annex II, entry 1488 · 30/07/2020
(Z)-2-Methoxymino-2-[2-(tritylamino)thiazol-4-yl]acetic acid
Source reference: Annex II, entry 1489 · 30/07/2020
Trisodium nitrilotriacetate
Source reference: Annex II, entry 1490 · 30/07/2020
2-Ethylhexyl-2-ethylhexanoate
Source reference: Annex II, entry 1491 · 30/07/2020
Diisobutyl phthalate
Source reference: Annex II, entry 1492 · 30/07/2020
Perfluorooctane sulfonic acid; heptadecafluorooctane-1-sulfonic acid [1]; Potassium perfluorooctanesulfonate; potassium heptadecafluorooctane-1-sulfonate [2]; Diethanolamine perfluorooctane sulfonate [3]; Ammonium perfluorooctane sulfonate; ammonium heptadecafluorooctanesulfonate [4]; Lithium perfluorooctane sulfonate; lithium heptadecafluorooctanesulfonate [5]
Source reference: Annex II, entry 1493 · 30/07/2020
Ethyl 1-(2,4-dichlorophenyl)5-(trichloromethyl)-1H-1,2,4-triazole-3-carboxylate
Source reference: Annex II, entry 1494 · 30/07/2020
1-Bromo-2-methylpropyl propionate
Source reference: Annex II, entry 1495 · 30/07/2020
Chloro-1-ethylcyclohexyl carbonate
Source reference: Annex II, entry 1496 · 30/07/2020
6,6'-Bis(diazo-5,5',6,6'-tetrahydro-5,5'-dioxo)[methylene-bis(5-(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulphonyloxy)-6-methyl-2-phenylene]di(naphthalene-1-sulfonate)
Source reference: Annex II, entry 1497 · 30/07/2020
Trifluralin (ISO); a,a,a-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine; 2,6-dinitro-N,N-dipropyl-4-trifluoromethylaniline; N,N-dipropyl-2,6-dinitro-4-trifluoromethylaniline
Source reference: Annex II, entry 1498 · 30/07/2020
4-Mesyl-2-nitrotoluene
Source reference: Annex II, entry 1499 · 30/07/2020
Rauwolfia serpentia L., alkaloids and their salts
Source reference: Annex II, entry 15 · 17/10/2010
Triammonium 4-[4-[7-(4-carboxylatoanilino)-1-hydroxy-3-sulfonato-2-naphthylazo]-2,5-dimethoxyphenylazo]benzoate
Source reference: Annex II, entry 1500 · 30/07/2020
Reaction mass of: triammonium 6-amino-3-((2,5-diethoxy-4-(3-phosphonophenyl)azo)phenyl)azo-4-hydroxy-2-naphthalenesulfonate; diammonium 3-((4-((7-amino-1-hydroxy-3-sulfo-naphthalen-2-yl)azo)-2,5-diethoxyphenyl)azo)benzoate
Source reference: Annex II, entry 1501 · 30/07/2020
N,N'-Diacetylbenzidine
Source reference: Annex II, entry 1502 · 30/07/2020
Market coverage contract
Complete annex dataset- Included scope
- Annexes II–VI: prohibited and restricted substances, colourants, preservatives and UV filters.
- If no match is found
- No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Complete verification checklist
- Confirm the exact INCI/CAS/EC identity.
- Review every matching Annex II–VI row and its conditions.
- Check SCCS opinions, CMR/nanomaterial rules and later amendments.
- Verify product classification, claims, labelling and responsible-person duties.
How European Union differs from other markets
Comparing this market's imported rules against every other market's for the same substance. A market with no imported rule for a substance is left out of that comparison rather than treated as permitting it.
A formula cleared elsewhere can fail here.
and 22 more — see the full comparison
Permitted here under conditions and prohibited, or more tightly held, elsewhere — so a formula built for this market may not travel.
and 103 more — see the full comparison
Official sources and legal role
PubChem PUG-View annotations
Attributed physical-property, hazard, environmental, use and literature annotations for uniquely matched PubChem compounds
Legal meaning: Scientific context aggregated by PubChem; individual values retain their named depositor or publication source
EMBL-EBI ChEBI 2.0
Curated definitions, chemical classes, roles, names, relationships and cross-references
Legal meaning: Curated scientific ontology; not a cosmetics permission or prohibition list
FDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Legal meaning: Identity registry only; UNII availability does not imply FDA review or approval
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Legal meaning: Independent expert review considered by FDA; not a government approval or binding market rule
EU Safety Gate cosmetic product alerts
Published cosmetic product alerts, notifying country, risk, product identifiers and corrective measures
Legal meaning: Official market-surveillance alerts; not proof that a named ingredient caused an incident
Available language: English and EU languages
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: European Commission.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English and EU languages.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.