ASEAN cosmetic ingredient regulations

3-Diethylaminopropyl cinnamate

CAS 538-66-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 130 · version 2026-1 · source checked 2026-08-30

3-Ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine

CAS 143860-04-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1163 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-4-(phenylazo)-2-naphthoic acid and its calcium salt

CAS 27757-79-5; 6371-76-2 · EC 228-899-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1331 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-4-[(2-hydroxynaphthyl)azo]-7-nitronaphthalene-1-

CAS 16279-54-2; 5610-64-0 · EC 227-029-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1323 · version 2026-1 · source checked 2026-08-30

3-Hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-

CAS 6535-46-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1346 · version 2026-1 · source checked 2026-08-30

3-Imidazol-4-ylacrylic acid and its ethyl ester (Urocanic acid)

CAS 104-98-3 · EC 203-258-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 418 · version 2026-1 · source checked 2026-08-30

3-Nitro-4-aminophenoxyethanol and its salts, when used as a

CAS 50982-74-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1250 · version 2026-1 · source checked 2026-08-30

3-Oxoandrost-4-ene-17-ß-carboxylic acid

CAS 302-97-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1488 · version 2026-1 · source checked 2026-08-30

3-[(2-nitro-4-(trifluoromethyl)phenyl)amino]propane-1,2-diol (HC

CAS 104333-00-8 · EC 410-010-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1324 · version 2026-1 · source checked 2026-08-30

3-[(4-(Acetylamino)phenyl)azo]-4-hydroxy-7-[[[[5-hydroxy-6-

CAS 3441-14-3 · EC 222-348-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1269 · version 2026-1 · source checked 2026-08-30

3-[[4-[(2-Hydroxyethyl)Methylamino]-2-Nitrophenyl]amino]-1,2-

CAS 173994-75-7; 102767-27-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1326 · version 2026-1 · source checked 2026-08-30

3-[[4-[(2-Hydroxyethyl)amino]-2-nitrophenyl]amino]-1,2-

CAS 114087-41-1; 114087-42-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1327 · version 2026-1 · source checked 2026-08-30

3-methylpyrazole

CAS 453-58-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1686 · version 2026-1 · source checked 2026-08-30

3H-Indolium, 2-(2-((2,4-dimethoxyphenyl)amino)ethenyl)-1,3,3-

CAS 4208-80-4 · EC 224-132-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1273 · version 2026-1 · source checked 2026-08-30

3H-Indolium, 2-[[(4-methoxyphenyl)methylhydrazono]methyl]-

CAS 54060-92-3 · EC 258-946-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1272 · version 2026-1 · source checked 2026-08-30

4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-

CAS 596-03-2; 4372-02-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1333 · version 2026-1 · source checked 2026-08-30

4'-Ethoxy-2-benzimidazoleanilide

CAS 120187-29-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1005 · version 2026-1 · source checked 2026-08-30

4,4'- Isobutylethylidenediphenol

CAS 6807-17-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1079 · version 2026-1 · source checked 2026-08-30

4,4'-(1,3-Phenylene-bis(1-methylethylidene))bis-phenol

CAS 13595-25-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1476 · version 2026-1 · source checked 2026-08-30

4,4'-(4-Iminocyclohexa-2,5-dienylidenemethylene) dianiline

CAS 69-61-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 706 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine

CAS 119-93-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 721 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine dihydrochloride

CAS 612-82-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 722 · version 2026-1 · source checked 2026-08-30

4,4'-Bi-o-toluidine sulphate

CAS 74753-18-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 724 · version 2026-1 · source checked 2026-08-30

4,4'-Bis(N-carbamoyl-4-

CAS 151882-81-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1467 · version 2026-1 · source checked 2026-08-30

4,4'-Bis(dimethylamino)benzophenone; (Michler's ketone)

CAS 90-94-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1149 · version 2026-1 · source checked 2026-08-30

4,4'-Carbonimidoylbis[N,N-dimethylaniline] and its salts

CAS 492-80-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1067 · version 2026-1 · source checked 2026-08-30

4,4'-Diaminodiphenylamine and its salts, when used as a

CAS 537-65-5 · EC 208-673-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1309 · version 2026-1 · source checked 2026-08-30

4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 207 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenebis(2-ethylaniline)

CAS 19900-65-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1038 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenedi-o-toluidine

CAS 838-88-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 707 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenedianiline

CAS 101-77-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 705 · version 2026-1 · source checked 2026-08-30

4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'- diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p- Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'- diisocyanate [3]; Methylenediphenyl diisocyanate [4]

4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'- diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p- Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'- diisocyanate [3]; Methylenediphenyl di

CAS 101-68-8 · EC 202-966-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1533 · version 2026-1 · source checked 2026-08-30

4,4'-Oxydianiline (p-aminophenyl ether) and its salts

CAS 101-80-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1160 · version 2026-1 · source checked 2026-08-30

4,4'-Thiodianiline and its salts

CAS 139-65-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1159 · version 2026-1 · source checked 2026-08-30

4,4'-[(4-Methyl-1,3-phenylene)bis(azo)]bis[6-methyl-1,3-

CAS 4482-25-1 · EC 224-764-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1296 · version 2026-1 · source checked 2026-08-30

4,4’-sulphonyldiphenol; bisphenol S

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1702 · version 2026-1 · source checked 2026-08-30

4,5-Diamino-1-((4-chlorophenyl)methyl)-1H-pyrazole sulfate,

CAS 163183-00-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1218 · version 2026-1 · source checked 2026-08-30

4,5-Diamino-1-methylpyrazole and its HCl salt, when used as a

CAS 20055-01-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1217 · version 2026-1 · source checked 2026-08-30

4,6-Bis(2-hydroxyethoxy)-m-phenylenediamine and its salts,

CAS 94082-85-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1307 · version 2026-1 · source checked 2026-08-30

4,6-Dimethyl-8-tert-butylcoumarin, when used as a fragrance

CAS 17874-34-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 430 · version 2026-1 · source checked 2026-08-30

4-(2,4-Dihydroxyphenylazo)benzenesulphonic acid and its

CAS 2050-34-2; 547-57-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1330 · version 2026-1 · source checked 2026-08-30

4-(4-Methoxyphenyl)-3-butene-2-one, when used as a fragrance

CAS 943-88-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 443 · version 2026-1 · source checked 2026-08-30

4-(Phenylazo)resorcinol (Solvent Orange 1; CI 11920) and its

CAS 2051-85-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1343 · version 2026-1 · source checked 2026-08-30

4-Amino-2-nitrophenol

CAS 119-34-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 412 · version 2026-1 · source checked 2026-08-30

4-Amino-3-fluorophenol

CAS 399-95-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1242 · version 2026-1 · source checked 2026-08-30

4-Amino-3-hydroxytoluene when used as a substance in hair

CAS 2835-98-5 · EC 220-620-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1643 · version 2026-1 · source checked 2026-08-30

4-Aminoazobenzene

CAS 60-09-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 990 · version 2026-1 · source checked 2026-08-30

4-Aminobenzenesulfonic acid and its salts, when used as a

CAS 121-57-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1257 · version 2026-1 · source checked 2026-08-30

4-Aminobenzoic acid and its esters, with the free amino group

CAS 94-09-7 · EC 202-303-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 167 · version 2026-1 · source checked 2026-08-30

4-Aminosalicylic acid and its salts

CAS 65-49-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 31 · version 2026-1 · source checked 2026-08-30