ASEAN cosmetic ingredient regulations

Bietamiverine (INN)

CAS 479-81-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 287 · version 2026-1 · source checked 2026-08-30

Bifenthrin (ISO); (2-methylbiphenyl-3-yl)methyl rel-(1R,3R)-3-

CAS 82657-04-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1558 · version 2026-1 · source checked 2026-08-30

Bifonazole

CAS 60628-96-8 · EC 262-336-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1725 · version 2026-1 · source checked 2026-08-30

Bimatoprost

CAS 155206-00-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference A1142 · version 2026-1 · source checked 2026-08-30

Binapacryl

CAS 485-31-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 688 · version 2026-1 · source checked 2026-08-30

Biphenyl-2-ol CAS No. 90-43-7

CAS 90-43-7 · EC 201-993-5

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol) · Avoid contact with eyes.

Source:ASEAN Annex VI, reference 7 · version 2026-1 · source checked 2026-08-30

Biphenyl-2-ylamine

CAS 90-41-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1116 · version 2026-1 · source checked 2026-08-30

Biphenyl-3,3',4,4'-tetrayltetraamine; diaminobenzidine

CAS 91-95-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1511 · version 2026-1 · source checked 2026-08-30

Biphenyl-4-ylamine and its salts

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 726 · version 2026-1 · source checked 2026-08-30

Bis(2-(2-methoxyethoxy)ethyl)ether; tetraglyme

CAS 143-24-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1663 · version 2026-1 · source checked 2026-08-30

Bis(2-chloroethyl) ether

CAS 111-44-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1174 · version 2026-1 · source checked 2026-08-30

Bis(cyclopentadienyl)-bis(2,6-difluoro-3-(pyrrol-1-yl)-

CAS 125051-32-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1009 · version 2026-1 · source checked 2026-08-30

Bis(α,α-dimethylbenzyl) peroxide

CAS 80-43-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1680 · version 2026-1 · source checked 2026-08-30

Bisphenol A (4,4'-Isopropylidenediphenol)

CAS 80-05-7 · EC 201-245-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1176 · version 2026-1 · source checked 2026-08-30

Bithionol (INN)

CAS 97-18-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 352 · version 2026-1 · source checked 2026-08-30

Boric acid, borates and tetraborates with the exception of substance No 1184 in Annex II CAS No 10043-35-3/11113-50-1

CAS 10043-35-3; 11113-50-1

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Talc (b) Products for oral hygiene (c) Other products (excluding bath products and hair waving products) · a) 5% (as boric acid) b) 0.1% (as boric acid) c) 3% (as boric acid) · (a) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin if the concentration of free soluble borates exceeds 1.5% (boric acid) (b) Not to be used in products for children under 3 years of age (c) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin if the concentration of free soluble borates exceeds 1.5% (as boric acid) Except Indonesia and Singapore – under review · (a) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin (b) 1. Not to be swallowed 2. Not to be used in products for children under 3 years of age (c) 1. Not to be used in products for children under 3 years of age 2. Not to be used on peeling or irritated skin

Source:ASEAN Annex III, reference 1a · version 2026-1 · source checked 2026-08-30

Bretylium tosilate (INN)

CAS 61-75-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 56 · version 2026-1 · source checked 2026-08-30

Brodifacoum (ISO); 4-hydroxy-3-(3-(4′-bromo-4-biphenylyl)-

CAS 56073-10-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1629 · version 2026-1 · source checked 2026-08-30

Bromadiolone (ISO); 3- [3-(4′-bromobiphenyl- 4-yl)-3-hydroxy-

CAS 28772-56-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1634 · version 2026-1 · source checked 2026-08-30

Bromine, elemental

CAS 7726-95-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 55 · version 2026-1 · source checked 2026-08-30

Bromisoval (INN)

CAS 496-67-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 58 · version 2026-1 · source checked 2026-08-30

Bromoethane

CAS 74-96-4

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1097 · version 2026-1 · source checked 2026-08-30

Bromoethylene

CAS 593-60-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 653 · version 2026-1 · source checked 2026-08-30

Bromomethane

CAS 74-83-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1094 · version 2026-1 · source checked 2026-08-30

Bromoxynil heptanoate (ISO)

CAS 56634-95-8

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1192 · version 2026-1 · source checked 2026-08-30

Brompheniramine (INN) and its salts

CAS 86-22-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 59 · version 2026-1 · source checked 2026-08-30

Bronopol (INN) CAS No. 52-51-7

CAS 52-51-7 · EC 200-143-0

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.1% · Avoid formation of nitrosamines

Source:ASEAN Annex VI, reference 21 · version 2026-1 · source checked 2026-08-30

Brucine

CAS 357-57-3

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 62 · version 2026-1 · source checked 2026-08-30

Bupirimate (ISO); 5-butyl-2-ethylamino-6- methylpyrimidin-4-yl

CAS 41483-43-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1639 · version 2026-1 · source checked 2026-08-30

Buta-1,3-diene

CAS 106-99-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 463 · version 2026-1 · source checked 2026-08-30

Butane, if it contains ≥ 0.1 % w/w Butadiene

CAS 106-97-8 · EC 203-448-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 465 · version 2026-1 · source checked 2026-08-30

Butanilicaine (INN) and its salts

CAS 3785-21-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 90 · version 2026-1 · source checked 2026-08-30

Butopiprine (INN) and its salts

CAS 55837-15-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 288 · version 2026-1 · source checked 2026-08-30

Butyl 4-hydroxybenzoate and its salts Propyl 4- hydroxybenzoate and its salts Butylparaben; CAS No. 94-26-8; Propylparaben; CAS No. 94-13-3 sodium propylparaben; CAS No. 35285-69-9 sodium butylparaben; CAS No. 36457-20-2 ; potassium butylparaben; CAS No. 38566-94-8; potassium propylparaben; CAS No. 84930-16- 5;

Butyl 4-hydroxybenzoate and its salts Propyl 4- hydroxybenzoate and its salts Butylparaben; CAS No. 94-26-8; Propylparaben; CAS No. 94-13-3 sodium propylparaben; CAS No. 35285-69-9 sodium butylparaben; CAS No. 36457-20-2 ; potassium butylparaben; CAS No.

CAS 94-26-8; 94-13-3; 35285-69-9; 36457-20-2; 38566-94-8; 84930-16-5 · EC 202-318-7

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.14 % (as acid) for the sum of the individual concentrations 0.8 % (as acid) for mixtures of substances mentioned in entry 12 and 12a, where the sum of the individual concentrations of butyl- and propylparaben and their salts does not exceed 0.14 % · Not to be used in leave-on products designed for application on the nappy area of children under three years of age. · For leave-on products designed for children under three years of age: “Do not use on the nappy area”’

Source:ASEAN Annex VI, reference 12a · version 2026-1 · source checked 2026-08-30

Butyl glycidyl ether

CAS 2426-08-6

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1050 · version 2026-1 · source checked 2026-08-30

C16-alkyltrimethylammonium chloride C18-alkyltrimethylammonium chloride Cetrimonium chloride CAS No. 112-02-7 Steartrimonium chloride CAS No. 112-03-8

CAS 112-02-7; 112-03-8 · EC 203-928-6

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Rinse-off hair products (b) Leave-on hair products (c) Face products · (a) 2.5 % for the individual concentrations or the sum of the individual concentrations of cetrimonium chloride and steartrimonium chloride (b) 1.0 % for the individual concentrations or the sum of the individual concentrations of cetrimonium chloride and steartrimonium chloride (c) 0.5 % for the individual concentrations or the sum of the individual concentrations of cetrimonium chloride and steartrimonium chloride · For purposes other than inhibiting the development of micro- organisms in the product. The purpose has to be apparent from the presentation of the product. As a preservative, see Annex VI Part 1, No 44.

Source:ASEAN Annex III, reference 286 · version 2026-1 · source checked 2026-08-30

C22-alkyltrimethylammonium chloride Behentrimonium chloride CAS No 17301-53-0

CAS 17301-53-0 · EC 241-327-0

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Rinse-off hair products (b) Leave-on hair products · (a) 5.0 % for the individual concentration of behentrimonium chloride or the sum of the individual concentrations of cetrimonium chloride, steartrimonium chloride and behentrimonium chloride, while at the same time respecting the relevant maximum concentration for the sum of cetrimonium chloride and steartrimonium chloride set out in entry 286. (b) 3.0 % for the individual concentration of behentrimonium chloride or the sum of the individual concentrations of cetrimonium chloride, steartrimonium chloride and behentrimonium chloride, while at the same time respecting the relevant maximum concentration for the sum of cetrimonium chloride and steartrimonium chloride set out in entry 286. · For purposes other than inhibiting the development of micro- organisms in the product. The purpose has to be apparent from the presentation of the product As a preservative, see Annex VI Part 1, No 44.

Source:ASEAN Annex III, reference 287 · version 2026-1 · source checked 2026-08-30

CBeAnSz aNlkoo. n1i2u1m-5 c4h-l0o ride, bromide and saccharinate (13) Benzalkonium chloride (CAS No. 8001-54-5, 63449-41-2, 68424-85-1, 68391-01-5, 61789- 71-7, 85409-22-9),Benzalkonium bromide (CAS No. 91080-29-4), Benzalkonium saccharinate (CAS No. 68989-01-5)

CBeAnSz aNlkoo. n1i2u1m-5 c4h-l0o ride, bromide and saccharinate (13) Benzalkonium chloride (CAS No. 8001-54-5, 63449-41-2, 68424-85-1, 68391-01-5, 61789- 71-7, 85409-22-9),Benzalkonium bromide (CAS No. 91080-29-4), Benzalkonium saccharinate (CAS No. 6898

CAS 8001-54-5; 63449-41-2; 68424-85-1; 68391-01-5; 61789-71-7; 85409-22-9; 91080-29-4; 68989-01-5 · EC 263-080-8

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

Conditions: 0.1% calculated as Benzalkonium chloride · athraonu nfodr t hoera el ycearse a unsde o. n the lips · - Avoid contact with the eyes

Source:ASEAN Annex VI, reference 54 · version 2026-1 · source checked 2026-08-30

CI Acid Black 131 and its salts, when used as a substance in

CAS 12219-01-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1252 · version 2026-1 · source checked 2026-08-30

CI Solvent Yellow 14

CAS 842-07-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1107 · version 2026-1 · source checked 2026-08-30

Cadmium and its compounds

CAS 7440-43-9

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 68 · version 2026-1 · source checked 2026-08-30

Cadmium carbonate

CAS 513-78-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1598 · version 2026-1 · source checked 2026-08-30

Cadmium hydroxide; cadmium dihydroxide

CAS 21041-95-2

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1599 · version 2026-1 · source checked 2026-08-30

Cadmium nitrate; cadmium dinitrate

CAS 10325-94-7

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1600 · version 2026-1 · source checked 2026-08-30

Calcium 3-hydroxy-4-[(1-sulphonato-2-naphthyl)azo]-2-

CAS 6417-83-0

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 1349 · version 2026-1 · source checked 2026-08-30

Calcium fluoride Calcium fluoride CAS No 7789-75-5

CAS 7789-75-5 · EC 232-188-7

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Oral hygiene products (except mouthwash) (b) Mouthwash · 0.15% calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15% · (a) & (b) Contains calcium fluoride (a) "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimise swallowing. In case of intake of fluoride from other sources consult a dentist or doctor." (12) (b) Do not use for children below 6 years of age

Source:ASEAN Annex III, reference 30 · version 2026-1 · source checked 2026-08-30

Calcium fluorophosphate Calcium monofluorophosphate CAS No 7789-74-4

CAS 7789-74-4 · EC 232-187-1

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Oral hygiene products (except mouthwash) (b) Mouthwash · 0.15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15 % · (a) & (b) Contains calcium monofluoro- phosphate. (a) “Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimize swallowing. In case of intake of fluoride from other sources consult a dentist or doctor.”(12) (b) Do not use for children below 6 years of age

Source:ASEAN Annex III, reference 29 · version 2026-1 · source checked 2026-08-30

Calcium hydroxide Calcium hydroxide CAS No 1305-62-0

CAS 1305-62-0 · EC 215-137-3

ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.

Conditions: (a) Hair straighteners containing two components: calcium hydroxide and a guanidine salt (b) pH adjuster – for depilatories (c) Other uses (eg. pH adjuster, processing aid) · (a) 7% by weight calcium hydroxide · (b) pH < 12.7 (c) pH < 11 · (a) • Contains alkali • Avoid contact with eyes • Can cause blindness • Keep out of reach of children (b) • Contains alkali • Keep out of reach of children • Avoid contact with eyes

Source:ASEAN Annex III, reference 15c · version 2026-1 · source checked 2026-08-30

Cantharides, Cantharis vesicatoria

CAS 92457-17-5

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 69 · version 2026-1 · source checked 2026-08-30

Captafol

CAS 2425-06-1

ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.

Source:ASEAN Annex II, reference 734 · version 2026-1 · source checked 2026-08-30