Canada cosmetic ingredient regulations
The Cosmetic Ingredient Hotlist records administrative prohibitions and restrictions.
- Regulator
- Health Canada
- Source language
- English and French
- Coverage version
- Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
Official ingredient records
580 matching recordsMephenesin and its esters
Canada Hotlist: Mephenesin and its esters
CAS 59-47-2
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 301 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Meprobamate
Canada Hotlist: Meprobamate
CAS 57-53-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 302 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Mercury and its compounds
Canada Hotlist: Mercury and its compounds
CAS 7439-97-6; 21908-53-2; 62-38-4; 94-43-9; 102-98-7; 6273-99-0; 54-64-8
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: Mercuric oxide; Phenyl mercuric acetate; Phenyl mercuric benzoate; Phenyl mercuric borate; Thimerosal
Source:Hotlist prohibited entry 303 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Mescaline and its salts
Canada Hotlist: Mescaline and its salts
CAS 54-04-6
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: 3,4,5-trimethoxyphenethylamine
Source:Hotlist prohibited entry 304 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metaldehyde
Canada Hotlist: Metaldehyde
CAS 9002-91-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 305 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metamfepramone and its salts
Canada Hotlist: Metamfepramone and its salts
CAS 15351-09-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 306 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metethoheptazine and its salts
Canada Hotlist: Metethoheptazine and its salts
CAS 509-84-2
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 307 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metformin and its salts
Canada Hotlist: Metformin and its salts
CAS 657-24-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 308 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methacrylic acid
Canada Hotlist: Methacrylic acid
CAS 79-41-4 · EC 201-204-4
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: a) Cosmetics that contain more than 5% methacrylic acid | b) Other cosmetics · Warnings: a) "This product contains methacrylic acid, is poisonous, is to be kept out of reach of children" and, "In the case of accidental ingestion, a Poison Control Centre or physician is to be contacted immediately."
Source:Hotlist restricted entry 52 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methapyrilene and its salts
Canada Hotlist: Methapyrilene and its salts
CAS 91-80-5
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 309 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metheptazine and its salts
Canada Hotlist: Metheptazine and its salts
CAS 469-78-3
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 310 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methocarbamol
Canada Hotlist: Methocarbamol
CAS 532-03-6
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 311 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methotrexate
Canada Hotlist: Methotrexate
CAS 59-05-2 · EC 200-413-8 (I)
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 312 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methoxydiglycol
Canada Hotlist: Methoxydiglycol
CAS 111-77-3 · EC 203-906-6
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: Diethylene glycol monomethyl ether; DEGME
Source:Hotlist prohibited entry 313 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methoxyethanol
Canada Hotlist: Methoxyethanol
CAS 109-86-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 314 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methoxyethanol acetate
Canada Hotlist: Methoxyethanol acetate
CAS 110-49-6 · EC 203-772-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 315 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methoxyisopropanol
Canada Hotlist: Methoxyisopropanol
CAS 107-98-2 · EC 203-539-1
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Synonyms or related compounds: Propylene glycol monomethyl ether · Maximum concentration: 0.5% of 2-methoxypropanol (1589-47-5)
Source:Hotlist restricted entry 53 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methoxyisopropyl acetate
Canada Hotlist: Methoxyisopropyl acetate
CAS 108-65-6; 84540-57-8 · EC 203-603-9
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Synonyms or related compounds: Propylene glycol monomethyl ether acetate. · Maximum concentration: 0.5% total of 2-methoxypropanol (1589-47-5) and/or 2-methoxypropyl-1-acetate (70657-70-4)
Source:Hotlist restricted entry 54 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl N-methyl anthranilate
Canada Hotlist: Methyl N-methyl anthranilate
CAS 85-91-6
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Maximum concentration: 0.1%
Source:Hotlist restricted entry 57 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl alcohol
Canada Hotlist: Methyl alcohol
CAS 67-56-1 · EC 200-659-6
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Synonyms or related compounds: Methanol | Cosmetics containing an amount of methyl alcohol equal to or greater than 5 ml must be packaged in a child-resistant container. Containers, that contain an amount of methyl alcohol equal or greater than 5 mL must meet the requirements set out in subsection 28.2 of the Cosmetic Regulations.
Source:Hotlist restricted entry 55 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl eugenol
Canada Hotlist: Methyl eugenol
CAS 93-15-2 · EC 202-223-0
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Permitted as a naturally occurring component in botanical extracts. | a) Fine fragrances | b) Eau de toilette | c) In a fragrance cream | d) Other leave-on products and in oral hygiene products | e) Rinse-off products · Maximum concentration: a) 0.01% | b) 0.004% | c) 0.002% | d) 0.0002% | e) 0.001%
Source:Hotlist restricted entry 56 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl methacrylate monomer
Canada Hotlist: Methyl methacrylate monomer
CAS 80-62-6 · EC 201-297-1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 316 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl salicylate
Canada Hotlist: Methyl salicylate
CAS 119-36-8 · EC 204-317-7
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Maximum concentration: 1%
Source:Hotlist restricted entry 58 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyl-trans-2-butenoate
Canada Hotlist: Methyl-trans-2-butenoate
CAS 623-43-8
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 319 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methylene Glycol
Canada Hotlist: Methylene Glycol
CAS 463-57-0 · EC 207-339-5
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: See " Formaldehyde ".
Source:Hotlist restricted entry 60 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methylene chloride
Canada Hotlist: Methylene chloride
CAS 75-09-2 · EC 200-838-9
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: Synonyms or related compounds: Dichloromethane | Not permitted in aerosol products.
Source:Hotlist restricted entry 59 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methylisothiazolinone (MI)
Canada Hotlist: Methylisothiazolinone (MI)
CAS 2682-20-4 · EC 220-239-6
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: a) Not permitted in leave-on products. · Maximum concentration: b) Rinse-off products Note: If MI is present in a formulation with Methylisothiazolinone / Methylchloroisothiazolinone (MI/MCI) in combination, the cumulative, total concentration of MI and MI/MCI may not exceed 0.0015%. · Warnings: b) 0.0015%
Source:Hotlist restricted entry 61 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methylisothiazolinone / Methylchloroisothiazolinone, in combination
Canada Hotlist: Methylisothiazolinone / Methylchloroisothiazolinone, in combination
CAS 26172-55-4; 2682-20-4
Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.
Conditions: a) Not permitted in leave-on products. · Maximum concentration: b) Rinse-off products Note: MCI is only permitted when present in combination with MI. If MI/MCI is present in a formulation with MI alone, the cumulative, total concentration of MI/MCI and MI may not exceed 0.0015%. · Warnings: b) 0.0015%
Source:Hotlist restricted entry 62 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyloxirane monomer
Canada Hotlist: Methyloxirane monomer
CAS 75-56-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: Propylene oxide
Source:Hotlist prohibited entry 317 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methylphenidate and its salts
Canada Hotlist: Methylphenidate and its salts
CAS 113-45-1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 318 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Methyprylon and its salts
Canada Hotlist: Methyprylon and its salts
CAS 125-64-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 320 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Metyrapone
Canada Hotlist: Metyrapone
CAS 54-36-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 321 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Minoxidil, its salts and derivatives
Canada Hotlist: Minoxidil, its salts and derivatives
CAS 38304-91-5 · EC 253-874-2
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 322 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Mofebutazone
Canada Hotlist: Mofebutazone
CAS 2210-63-1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 323 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Morpholine and its salts
Canada Hotlist: Morpholine and its salts
CAS 110-91-8 · EC 203-815-1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 324 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Musk ambrette
Canada Hotlist: Musk ambrette
CAS 83-66-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: 4- tert -butyl-3-methoxy-2,6-dinitrotoluene
Source:Hotlist prohibited entry 325 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Musk tibetene
Canada Hotlist: Musk tibetene
CAS 145-39-1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: 1- tert -butyl-3,4,5-trimethyl-2,6-dinitrobenzene
Source:Hotlist prohibited entry 326 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
N,N-bis(2-Chloroethyl)methylamine N-oxide and its salts
Canada Hotlist: N,N-bis(2-Chloroethyl)methylamine N-oxide and its salts
CAS 126-85-2
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: Nitrogen mustard N-oxide
Source:Hotlist prohibited entry 327 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
N-5-Chlorobenzoxazol-2-ylacetamide and its salts
Canada Hotlist: N-5-Chlorobenzoxazol-2-ylacetamide and its salts
CAS 35783-57-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 328 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nalorphine, its salts and ethers
Canada Hotlist: Nalorphine, its salts and ethers
CAS 62-67-9
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 329 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Naphazoline and its salts
Canada Hotlist: Naphazoline and its salts
CAS 835-31-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 330 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Naphthalene
Canada Hotlist: Naphthalene
CAS 91-20-3
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 331 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Narcotics, natural and synthetic
Canada Hotlist: Narcotics, natural and synthetic
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 332 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Neodymium and its salts
Canada Hotlist: Neodymium and its salts
CAS 7440-00-8
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 333 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Neostigmine and its salts
Canada Hotlist: Neostigmine and its salts
CAS 59-99-4
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 334 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nerium oleander , its extracts and its glycosides
Canada Hotlist: Nerium oleander , its extracts and its glycosides
CAS 465-16-7; 84929-39-5 · EC 284-522-6
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Conditions: Synonyms or related compounds: Oleandrin; Digitoxigenin; Neriin; Folinerin; Rosagenin
Source:Hotlist prohibited entry 335 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nicotine and its salts
Canada Hotlist: Nicotine and its salts
CAS 54-11-5
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 336 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nitrites, amyl
Canada Hotlist: Nitrites, amyl
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 337 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nitrites, inorganic, except sodium nitrite
Canada Hotlist: Nitrites, inorganic, except sodium nitrite
CAS 14797-65-0
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 338 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Nitrobenzene
Canada Hotlist: Nitrobenzene
CAS 98-95-3
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Source:Hotlist prohibited entry 339 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30
Market coverage contract
Complete Hotlist snapshot- Included scope
- All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.
- If no match is found
- The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
Complete verification checklist
- Search English/French names and CAS identifiers.
- Apply every restriction, concentration and label warning.
- Check Food and Drugs Act/Cosmetic Regulations requirements.
- Recheck the current Hotlist before notification or sale.
Official sources and legal role
Health Canada Cosmetic Ingredient Hotlist
Administrative prohibitions, restrictions, conditions and warning requirements
Legal meaning: Official Health Canada compliance indicator; not a complete safety clearance
Available language: English / French
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: Health Canada.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English and French.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.