Canada cosmetic ingredient regulations

Tripelennamine

Canada Hotlist: Tripelennamine

CAS 91-81-6

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 473 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Tuaminoheptane, its isomers and salts

Canada Hotlist: Tuaminoheptane, its isomers and salts

CAS 123-82-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 474 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Urea

Canada Hotlist: Urea

CAS 57-13-6 · EC 200-315-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Cosmetics intended to be diluted in bath water | b) Other cosmetics · Maximum concentration: b) 10%

Source:Hotlist restricted entry 87 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Urea (carbamide) peroxide

Canada Hotlist: Urea (carbamide) peroxide

CAS 124-43-6 · EC 204-701-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Peroxide and peroxide-generating compounds ".

Source:Hotlist restricted entry 88 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Urginea scilla Stern . and its galenical preparations

Canada Hotlist: Urginea scilla Stern . and its galenical preparations

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 475 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Vaccines

Canada Hotlist: Vaccines

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 476 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Valnoctamide

Canada Hotlist: Valnoctamide

CAS 4171-13-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 477 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Veratrine, its salts and galenical preparations

Canada Hotlist: Veratrine, its salts and galenical preparations

CAS 62-59-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 478 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Veratrum spp . and their preparations

Canada Hotlist: Veratrum spp . and their preparations

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 479 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Versalide

Canada Hotlist: Versalide

CAS 88-29-9

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 480 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Vinyl chloride monomer

Canada Hotlist: Vinyl chloride monomer

CAS 75-01-4 · EC 200-831-0

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 481 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Warfarin and its salts

Canada Hotlist: Warfarin and its salts

CAS 81-81-2

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 482 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Xanthinol

Canada Hotlist: Xanthinol

CAS 2530-97-4

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 483 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Xylidines, their isomers, salts, halogenated and sulfonated derivatives

Canada Hotlist: Xylidines, their isomers, salts, halogenated and sulfonated derivatives

CAS 1300-73-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 484 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Xylometazoline and its salts

Canada Hotlist: Xylometazoline and its salts

CAS 526-36-3

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 485 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Yohimbine and its salts

Canada Hotlist: Yohimbine and its salts

CAS 146-48-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 486 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Zinc peroxide

Canada Hotlist: Zinc peroxide

CAS 1314-22-3 · EC 215-226-7

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: See " Peroxide and peroxide-generating compounds ".

Source:Hotlist restricted entry 89 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Zirconium and its compounds

Canada Hotlist: Zirconium and its compounds

CAS 7440-67-7 · EC 231-176-9

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Not permitted in aerosol dispensers. | Permitted as aluminum zirconium complexes and as zirconium lakes, salts and pigments of colouring agents only. See also " Aluminum zirconium complexes ". | Table 2 notes Table 2 note 1 Cells in this column are left blank when the substance does not have a known CAS . Return to table 2 note 1 referrer Table 2 note 2 Cells in this column are left blank when no synonyms or related compounds are provided for the entry. Return to table 2 note 2 referrer Table 2 note 3 Cells in this column are left blank when no condition of use is specified and the restriction applies to all cosmetic products. Return to table 2 note 3 referrer Table 2 note 4 Cells in this column are left blank when no maximum concentration is specified. Return to table 2 note 4 referrer Table 2 note 5 Cells in this column are left blank when no warning or cautionary statements are specified. Return to table 2 note 5 referrer

Source:Hotlist restricted entry 90 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

Zoxazolamine

Canada Hotlist: Zoxazolamine

CAS 61-80-3

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 487 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

m -Cresol

Canada Hotlist: m -Cresol

CAS 95-48-7; 108-39-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics intended to be used on or around mucosal membranes such as eyes, mouth or nose | b) Other cosmetics · Maximum concentration: 0.1% · Warnings: "Do not use in the area of the eye, mouth or nose"

Source:Hotlist restricted entry 51 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

o -Cresol

Canada Hotlist: o -Cresol

CAS 95-48-7; 108-39-4

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: a) Not permitted in cosmetics intended to be used on or around mucosal membranes such as eyes, mouth or nose | b) Other cosmetics · Maximum concentration: 0.1% · Warnings: "Do not use in the area of the eye, mouth or nose"

Source:Hotlist restricted entry 63 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

o -Phenylenediamine and its salts

Canada Hotlist: o -Phenylenediamine and its salts

CAS 95-54-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 353 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

p -Chloro- m -cresol

Canada Hotlist: p -Chloro- m -cresol

CAS 59-50-7 · EC 200-431-6

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: Chlorocresol | a) Not permitted in cosmetics intended to be used on or around mucosal membranes such as eyes, mouth or nose | b) Other cosmetics · Maximum concentration: 0.1% · Warnings: "Do not use in the area of the eye, mouth or nose"

Source:Hotlist restricted entry 64 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

p -Hydroxyanisole

Canada Hotlist: p -Hydroxyanisole

CAS 150-76-5 · EC 205-769-8

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: 4-Methoxyphenol | Permitted only in nail products. · Maximum concentration: 0.1% If hydroquinone and p-hydroxyanisole are used in the same product, the total concentration of the 2 ingredients may not exceed 0.1% · Warnings: "Avoid skin contact" "Read directions carefully before using"

Source:Hotlist restricted entry 66 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

p -Phenylenediamine and its salts

Canada Hotlist: p -Phenylenediamine and its salts

CAS 106-50-3; 624-18-0; 16245-77-5

Health Canada lists this ingredient as restricted; the listed conditions and warnings apply.

Conditions: Synonyms or related compounds: p -Phenylenediamine HCL; p -Phenylenediamine sulfate | a) Not permitted in products intended for use on the skin. Additionally see " Coal tar dye ". | b) Oxidative hair dyes · Maximum concentration: b) 3% after dilution with an oxidizer · Warnings: b) On the inner label and the outer label of the cosmetic: "CAUTION: This product contains ingredients that may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dying the eyelashes or eyebrows. To do so may cause blindness." Instructions to the following effect accompany each package of hair dye: the preparation may cause serious inflammation of the skin in some persons and a preliminary test should always be carried out to determine whether or not special sensitivity exists; and to make the test, a small area of skin behind the ear or on the inner surface of the forearm should be cleansed, using either soap and water or alcohol, and a small quantity of the hair dye as prepared for use should be applied to the area and allowed to dry. After 24 hours, the area should be washed gently with soap and water. If no irritation or inflammation is apparent, it is usually assumed that no hypersensitivity to the dye exists. The test should, however, be carried out before each application. On no account should the hair dye be used for dyeing eyebrows or eyelashes as severe inflammation of the eye or even blindness may result.

Source:Hotlist restricted entry 69 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

p-Cresol and mixtures thereof

Canada Hotlist: p-Cresol and mixtures thereof

CAS 106-44-5; 1319-77-3

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: Mixed cresols

Source:Hotlist prohibited entry 356 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

trans -2-Heptenal

Canada Hotlist: trans -2-Heptenal

CAS 18829-55-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 461 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

α-Methylanisalacetone

Canada Hotlist: α-Methylanisalacetone

CAS 104-27-8

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Conditions: Synonyms or related compounds: 1-(4-methoxyphenyl)-1-pentene-3-one

Source:Hotlist prohibited entry 488 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

α-Santonin

Canada Hotlist: α-Santonin

CAS 481-06-1

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 489 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30

β-Eucaine

Canada Hotlist: β-Eucaine

CAS 500-34-5

Health Canada lists this ingredient as prohibited for use in cosmetic products.

Source:Hotlist prohibited entry 490 · version Health Canada Hotlist 2025-08-13 · source checked 2026-08-30