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InventoryRef 3883815/10/2010

UREA

Urea

UREA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

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MarketEvidence statusRecordsSource language
European UnionSource mapped
Inventory entry; no linked annex rule
0English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaEvidence linked
Restricted
Open this evidence		1English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Restricted
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 57-13-6
CAS 57-13-6PubChem CID 1176

Urea

Urea is a carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). It has a role as a fertilizer, a flour treatment agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a Daphnia magna metabolite. It is a monocarboxylic acid amide and a one-carbon compound. It is functionally related to a carbonic acid. It is a tautomer of a carbamimidic acid. — ChEBI

IUPAC name
urea
Molecular formula
CH4N2O
Molecular weight
60.056 g/mol
Exact mass
60.032362755 Da
XLogP3
-1.4
Topological polar surface area
69.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

carbamideCarbonyldiamideUreophilCarbonyldiamineUreaphilKeratinaminUrevertAlphadrate
16 more reported names
AquadrateCarbadermPastaronUrepearlCarbonyl diamideCarbamide resinUltra MideVarioform iiAqua CareHarnstoffMocovinaNutraplusPrespersion, 75 ureaSupercel 3000Aqua Care HPUreacin-10 lotion
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for UREA

INCI name

UREA

INN name

urea

Ph. Eur. name

ureum

Description

Urea

Record provenance

Inventory reference
38838
Imported identity
UREA
Source update
15/10/2010
European Commission CosIng source notes
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Browse EU annexes

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Key data

CAS
57-13-6
EC
200-315-5
Restriction
—
Function
ANTISTATIC
Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
BUFFERING
Stabilising the pH of an aqueous medium in a narrow range even if an acid or base is added. Altering and/or maintaining a cosmetic product's pH at the desired level.
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29684 · UREA

Ingredients with overlapping formulation functions

TRISODIUM SULFOSUCCINATEBUFFERING, CHELATING, SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE
TRITICUM VULGARE PROTEINBUFFERING, FILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN …
TRITICUM VULGARE SEED EXTRACTBUFFERING, DETANGLING, SKIN CONDITIONING, SKIN PROTECTING
TROMETHAMINEBUFFERING, FRAGRANCE
URIC ACIDBUFFERING, SKIN CONDITIONING
ZINC CARBONATE HYDROXIDEBUFFERING, BULKING
ZINC GLYCINATEBUFFERING
ZINC HEXAMETAPHOSPHATEANTICORROSIVE, BUFFERING, CHELATING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How UREA appears in the CosIng inventory

The CosIng inventory lists UREA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

UREA is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

UREA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, UREA carries the following function designation(s):

CAS 57-13-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for UREA

This page reproduces the CosIng inventory entry for UREA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research UREA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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