ASEAN cosmetic ingredient regulations
Regional annexes require member-state effective-date and deviation checks.
- Regulator
- ASEAN Cosmetic Committee / national regulators
- Source language
- English and national languages
- Coverage version
- ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
What this list is
The ASEAN Cosmetic Directive is not law anywhere by itself. Each member state enacts it separately, on its own date, sometimes with its own changes — so a regional answer is a starting point, not a compliance answer.
- 2,224 regional records: 1,728 prohibited, 249 restricted, 247 on a positive list.
- The directive is agreed regionally and given force by each member state's own instrument.
- Effective dates differ between member states, so the same annex can be in force in one and not another.
- Member states may add national requirements the regional annexes do not contain.
The ASEAN Cosmetic Directive harmonises the annexes across ten member states, and it is genuinely useful for that: one set of prohibited, restricted and positive lists covering a region that would otherwise need ten separate checks. What it is not is directly binding. The directive takes effect in a member state when that state gives it effect in national law, and those instruments are made at different times.
Two consequences follow, and both bite in practice. An annex amendment agreed regionally may be in force in Singapore and not yet in Indonesia, so the same substance can have two different answers on the same day. And a member state may impose requirements of its own — notification procedures, labelling in a national language, additional restrictions — that the regional annexes say nothing about.
Treat what follows as the regional baseline. For a product going to a specific market, the national instrument and its current effective date are the answer, and this list is where to start rather than where to stop.
Checked against
Official ingredient records
2224 matching recordsMethyloxirane
CAS 75-56-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 655 · version 2026-1 · source checked 2026-08-30
Methylphenidate (INN) and its salts
CAS 113-45-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 175 · version 2026-1 · source checked 2026-08-30
Methylphenylenediamines, their N-substituted derivatives and their salts (1) with the exception of the substances under reference numbers 9a and 9b in this Annex and substances under reference numbers 364, 1310 and 1313 in Annex II
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Conditions: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 5 % calculated as free base The direction for use “wear suitable gloves” must be included in label or leaflet text. · To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16.
Source:ASEAN Annex III, reference 9 · version 2026-1 · source checked 2026-08-30
Methyprylon (INN) and its salts
CAS 125-64-4
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 133 · version 2026-1 · source checked 2026-08-30
Metosulam (ISO); N-(2,6-dichloro-3-methylphenyl)-5,7-
CAS 139528-85-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1591 · version 2026-1 · source checked 2026-08-30
Metyrapone (INN)
CAS 54-36-4
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 292 · version 2026-1 · source checked 2026-08-30
Miconazole [1]; Miconazole Nitrate [2]
CAS 22916-47-8; 22832-87-7 · EC 245-256-6
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1724 · version 2026-1 · source checked 2026-08-30
Mineral wool, with the exception of those specified elsewhere in
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1127 · version 2026-1 · source checked 2026-08-30
Mixture of (1), (2) & (3) in dispersing agent (lignosulphate): (1) 9,10-Anthracenedione- 1,4-bis[(2- Hydroxyethyl)amino] (2) 9,10-Anthracenedione-1- [(2- Hydroxyethyl)amino]- 4-[(3- Hydroxypropyl)amino] (3) 9,10-anthracenedione- 1,4-bis[(3- hydroxypropyl)amino Disperse Blue 377 is a mixture of three dyes: (1) 1,4-bis[(2- hydroxyethyl)amino]anthra-9,10- quinone (2) 1-[(2-hydroxyethyl)amino]-4-[(3- hydroxypropyl)amino]anthra- 9,10- quinone (3) 1,4-bis[(3- hydroxypropyl)amino]anthra- 9,10- quinone CAS No (1) 4471-41- 4 (2) 67674- 26-4 (3) 67701- 36-4
Mixture of (1), (2) & (3) in dispersing agent (lignosulphate): (1) 9,10-Anthracenedione- 1,4-bis[(2- Hydroxyethyl)amino] (2) 9,10-Anthracenedione-1- [(2- Hydroxyethyl)amino]- 4-[(3- Hydroxypropyl)amino] (3) 9,10-anthracenedione- 1,4-bis[(3- hydroxypropyl)
CAS 4471-41-4; 67674-26-4; 67701-36-4 · EC 266-865-3
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Conditions: Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · 2.0% · The direction for use “wear suitable gloves” must be included in label or leaflet text. · Do not use to dye eyelashes or eyebrows
Source:ASEAN Annex III, reference 295 · version 2026-1 · source checked 2026-08-30
Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)- one and 2-Methylisothiazol-3(2H)-one (INCI) Methylchloroisothiazolinone (and) Methylisothiazolinone(9) CAS No. 26172-55-4, 2682-20-4, 55965-84-9
CAS 26172-55-4; 2682-20-4; 55965-84-9 · EC 247-500-7
ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions: 0,0015 % (of a mixture in the ratio 3:1 of 5-chloro- 2- methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one) · Rinse-off products
Source:ASEAN Annex VI, reference 39 · version 2026-1 · source checked 2026-08-30
Mofebutazone (INN)
CAS 2210-63-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 64 · version 2026-1 · source checked 2026-08-30
Molinate (ISO)
CAS 2212-67-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1180 · version 2026-1 · source checked 2026-08-30
Molybdenum trioxide
CAS 1313-27-5
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1465 · version 2026-1 · source checked 2026-08-30
Monoalkylamines, monoalkanolamines and their salts
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Conditions: Maximum secondary amine content: 0.5% · • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content : 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 g/kg(21) • Keep in nitrite-free containers
Source:ASEAN Annex III, reference 61 · version 2026-1 · source checked 2026-08-30
Monocrotophos
CAS 6923-22-4
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1092 · version 2026-1 · source checked 2026-08-30
Monosodium salt of 2,2'-(1,4-phenylene)bis)-1H- benzimidazole-4,6-disulphonic acid CAS No.180898-37-7
CAS 180898-37-7 · EC 29-750-0
ASEAN Annex VII lists this record among UV filters allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions: 10% (of acid)
Source:ASEAN Annex VII, reference 24 · version 2026-1 · source checked 2026-08-30
Monuron
CAS 150-68-5
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1025 · version 2026-1 · source checked 2026-08-30
Morpholine and its salts
CAS 110-91-8 · EC 203-815-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 344 · version 2026-1 · source checked 2026-08-30
Morpholine-4-carbonyl chloride
CAS 15159-40-7
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1026 · version 2026-1 · source checked 2026-08-30
Moved or Deleted (See Ref. No. 1067)
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1129 · version 2026-1 · source checked 2026-08-30
Moved or Deleted (See Ref. No. 195)
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1130 · version 2026-1 · source checked 2026-08-30
Myclobutanil; 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-
CAS 88671-89-0
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1114 · version 2026-1 · source checked 2026-08-30
N'-(4-Chloro-o-tolyl)-N,N-dimethylformamidine
CAS 19750-95-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1037 · version 2026-1 · source checked 2026-08-30
N,N',N''-Tris(2-methyl-2,3-epoxypropyl)-perhydro-2,4,6-oxo-
CAS 26157-73-3
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1531 · version 2026-1 · source checked 2026-08-30
N,N',N'-Tris(polyoxyethylene)-N- hexadecylpropylenediamine dihydrofluoride
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Conditions: (a) Oral hygiene products (except mouthwash) (b) Mouthwash · 0.15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0.15 % · (a) & (b) Contains N,N',N'-tris(polyoxy- ethylene) -N-hexadecylpropylene- diamine dihydrofluoride (a) "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimize swallowing. In case of intake of fluoride from other sources consult a dentist or doctor.”(12) (b) Do not use for children below 6 years of age
Source:ASEAN Annex III, reference 38 · version 2026-1 · source checked 2026-08-30
N,N'-Diacetylbenzidine
CAS 613-35-4
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1502 · version 2026-1 · source checked 2026-08-30
N,N'-Dihexadecyl-N,N'-bis(2-hydroxyethyl)propanediamide;
CAS 149591-38-8 · EC 422-560-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1243 · version 2026-1 · source checked 2026-08-30
N,N'-Dimethyl-N-Hydroxyethyl-3-nitro-p-phenylenediamine and
CAS 10228-03-2 · EC 233-549-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1288 · version 2026-1 · source checked 2026-08-30
N,N'-Methylenedimorpholine; N,N'-methylenebismorpholine;
CAS 5625-90-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1605 · version 2026-1 · source checked 2026-08-30
N,N'-Pentamethylenebis(trimethylammonium) salts, e.g.
CAS 541-20-8
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 120 · version 2026-1 · source checked 2026-08-30
N,N'-[(Methylimino)diethylene]bis(ethyldimethylammonium)
CAS 306-53-6
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 121 · version 2026-1 · source checked 2026-08-30
N,N,N',N'-Tetraglycidyl-4,4'-diamino-3,3'-diethyldiphenylmethane
CAS 130728-76-6
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1010 · version 2026-1 · source checked 2026-08-30
N,N,N',N'-Tetramethyl-4,4'-methylendianiline
CAS 101-61-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1161 · version 2026-1 · source checked 2026-08-30
N,N,N-Trimethyl-4-(2-oxoborn-3-ylidene methyl) anilinium methyl sulphate CAS No.52793-97-2
CAS 52793-97-2 · EC 258-190-8
ASEAN Annex VII lists this record among UV filters allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions: 6%
Source:ASEAN Annex VII, reference 2 · version 2026-1 · source checked 2026-08-30
N,N-(Dimethylamino)thioacetamide hydrochloride
CAS 27366-72-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1537 · version 2026-1 · source checked 2026-08-30
N,N-Diethyl-m-aminophenol, when used as a substance in hair
CAS 91-68-9 · EC 202-090-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1223 · version 2026-1 · source checked 2026-08-30
N,N-Diethyl-p-phenylenediamine and its salts, when used as a substance in hair dye products
CAS 93-05-0
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1311 · version 2026-1 · source checked 2026-08-30
N,N-Dimethyl-2,6-pyridinediamine and its HCl salt, when used
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1224 · version 2026-1 · source checked 2026-08-30
N,N-Dimethyl-p-phenylenediamine and its salts, when used as a
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1312 · version 2026-1 · source checked 2026-08-30
N,N-Dimethylacetamide
CAS 127-19-5
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 747 · version 2026-1 · source checked 2026-08-30
N,N-Dimethylaniline
CAS 121-69-7
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1007 · version 2026-1 · source checked 2026-08-30
N,N-Dimethylanilinium tetrakis(pentafluorophenyl)borate
CAS 118612-00-3
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1184 · version 2026-1 · source checked 2026-08-30
N,N-Dimethylformamide
CAS 68-12-2
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 743 · version 2026-1 · source checked 2026-08-30
N,N-bis (2-Chloroethyl)methylamine N-oxide and its salts
CAS 126-85-2
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 86 · version 2026-1 · source checked 2026-08-30
N,N-diethyl-m-toluamide/Diethyltoluamide (DEET)
CAS 134-62-3
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference A1144 · version 2026-1 · source checked 2026-08-30
N,N’-Hexamethylenebis (trimethylammonium) salts, e.g.
CAS 55-97-0
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 124 · version 2026-1 · source checked 2026-08-30
N-(2-Hydroxyethyl)-2-nitro-4- trifluormethyl-aniline HC Yellow No 13 CAS No 10442-83-8
CAS 10442-83-8 · EC 443-760-2
ASEAN Annex III lists this record among substances allowed only under restrictions and conditions. Member-state transition rules and deviations still require local verification.
Conditions: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. · (b) 2.5% · (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.5% For (a) and (b): - Do not use with nitrosating agents - Maximum nitrosamine content: 50µg/kg(21) - Keep in nitrite-free containers. The direction for use “wear suitable gloves” must be included in label or leaflet text. · (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary “black henna” tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source:ASEAN Annex III, reference 273 · version 2026-1 · source checked 2026-08-30
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt, when
CAS 72584-59-9
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1226 · version 2026-1 · source checked 2026-08-30
N-(2-Nitro-4-aminophenyl)-allylamine (HC Red No 16) and its
CAS 160219-76-1
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1373 · version 2026-1 · source checked 2026-08-30
N-(2-nitrophenyl)phosphoric triamide
CAS 74819-71-3
ASEAN Annex II lists this record among substances prohibited in cosmetic products. Member-state transition rules and deviations still require local verification.
Source:ASEAN Annex II, reference 1712 · version 2026-1 · source checked 2026-08-30
Market coverage contract
Complete regional annex dataset- Included scope
- Annexes II, III, IV, VI and VII covering prohibited, restricted and positive-list substances.
- If no match is found
- Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.
Complete verification checklist
- Search all ACD annexes by name and identifiers.
- Apply product type, maximum level and warning conditions.
- Confirm the target member state's adoption and transition date.
- Complete the local notification and responsible-company requirements.
Official sources and legal role
ASEAN Cosmetic Directive annexes
Banned, restricted and positive-list substances under the harmonised ASEAN framework
Legal meaning: Regional directive; member-state transitions and deviations still require local verification
Available language: English
What this market page can answer
Source and authority
Identify the official material and the regulator responsible for it: ASEAN Cosmetic Committee / national regulators.
Language and scope
See whether usable English or bilingual material exists and what the mapped source actually covers. Current source language: English and national languages.
Evidence status
Browse ingredient-level records imported from official sources. Each row states whether it passed deterministic source checks or human editorial review.
How to verify an ingredient for this market
- Search the ingredient by INCI name, CAS number or EC number and record the exact identity.
- Open each official source above and check the current version, product scope, concentration limits and required warnings.
- Confirm effective dates and whether an English text is official, reviewed or only contextual.
- Treat a missing local match as unknown, never as permission or a safety conclusion.