What does the restriction note for BISHYDROXYETHYL BISCETYL MALONAMIDE mean?

The restriction field for BISHYDROXYETHYL BISCETYL MALONAMIDE reads: II/1243. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 149591-38-8?

CAS 149591-38-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains BISHYDROXYETHYL BISCETYL MALONAMIDE?

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InventoryRef 3219215/10/2010

BISHYDROXYETHYL BISCETYL MALONAMIDE

Propanediamide, N,N'-bis(2-hydroxyethyl)-N,N'-bis(hexadecyl)-

BISHYDROXYETHYL BISCETYL MALONAMIDE is linked to 1 EU annex record on this page. Inventory note: II/1243.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 149591-38-8

CAS 149591-38-8PubChem CID 9809545

Bishydroxyethyl biscetyl malonamide

IUPAC name: N,N'-dihexadecyl-N,N'-bis(2-hydroxyethyl)propanediamide

Molecular formula: C39H78N2O4
Molecular weight: 639.0 g/mol
Exact mass: 638.59615897 Da
XLogP3: 13.5
Topological polar surface area: 81.1 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Questamide H913CU8H33EPROPANEDIAMIDE, N1,N3-DIHEXADECYL-N1,N3-BIS(2-HYDROXYETHYL)-EC 422-560-9Propanediamide, N,N'-dihexadecyl-N,N'-bis(2-hydroxyethyl)-RefChem:569457BISHYDROXYETHYL BISCETYL MALONAMIDE [INCI]422-560-9

3 more reported names

UNII-913CU8H33ERHIIHYCQYFKTHL-UHFFFAOYSA-NN~1~,N~3~-Dihexadecyl-N~1~,N~3~-bis(2-hydroxyethyl)propanediamide

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID60933683

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for BISHYDROXYETHYL BISCETYL MALONAMIDE

INCI name

BISHYDROXYETHYL BISCETYL MALONAMIDE

Description

Propanediamide, N,N'-bis(2-hydroxyethyl)-N,N'-bis(hexadecyl)-

Record provenance

Inventory reference: 32192
Imported identity: BISHYDROXYETHYL BISCETYL MALONAMIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for BISHYDROXYETHYL BISCETYL MALONAMIDE

Annex II Restriction reference

Entry 1243

N,N'-Dihexadecyl-N,N'-bis(2-hydroxyethyl)propanediamide; Bishydroxyethyl Biscetyl Malonamide

CAS: 149591-38-8

EC: 422-560-9

Key data

CAS

149591-38-8

422-560-9

Restriction

II/1243

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#3693 · BISHYDROXYETHYL BISCETYL MALONAMIDE

Ingredients with overlapping formulation functions

BIS-PALMITOYLOXYCAPRAMIDO ISOPROPANOLSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

BIS-RETINAMIDO METHYLPENTANEANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

BIS-THYMINEMETHYL ACETIC ACIDANTIOXIDANT; BLEACHING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT

BIS-VINYL DIPHENYL DIMETHICONEFILM FORMING, HAIR CONDITIONING, SKIN PROTECTING

BIXA ORELLANA LEAF EXTRACTANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

BLACK SOLDIER FLY LARVA OILSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

BLETILLA STRIATA CALLUS EXTRACTANTIOXIDANT, SKIN PROTECTING

BLETILLA STRIATA CALLUS POWDERANTIOXIDANT, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How BISHYDROXYETHYL BISCETYL MALONAMIDE appears in the CosIng inventory

The CosIng inventory lists BISHYDROXYETHYL BISCETYL MALONAMIDE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

BISHYDROXYETHYL BISCETYL MALONAMIDE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

BISHYDROXYETHYL BISCETYL MALONAMIDE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for BISHYDROXYETHYL BISCETYL MALONAMIDE reads: "II/1243". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, BISHYDROXYETHYL BISCETYL MALONAMIDE carries the following function designation(s):

CAS 149591-38-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for BISHYDROXYETHYL BISCETYL MALONAMIDE

This page combines the CosIng inventory entry for BISHYDROXYETHYL BISCETYL MALONAMIDE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research BISHYDROXYETHYL BISCETYL MALONAMIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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