SALICYLIC ACID, CALCIUM SALICYLATE, MAGNESIUM SALICYLATE, MEA- SALICYLATE, SODIUM SALICYLATE, POTASSIUM SALICYLATE, TEA- SALICYLATE

CAS 18917-89-0PubChem CID 54684589

(T-4)-Bis(2-(hydroxy-kappaO)benzoato-kappaO)magnesium

Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often found with a half dosage, with reduced anti-inflammatory results. — DrugBank

IUPAC name

magnesium bis(2-carboxyphenolate)

Molecular formula

C14H10MgO6

Molecular weight

298.53 g/mol

Exact mass

298.0327797 Da

Topological polar surface area

121.0 Ų

Hydrogen-bond donors

2

Hydrogen-bond acceptors

6

Covalent units

3

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

CAS 2174-16-5PubChem CID 25213

Trolamine Salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine salicylate has no distinct odor which improves patient acceptability. It also displays low systemic absorption upon dermal or topical administration and has low skin irritant properties. As with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains. — DrugBank

IUPAC name

2-[bis(2-hydroxyethyl)amino]ethanol;2-hydroxybenzoic acid

Molecular formula

C13H21NO6

Molecular weight

287.31 g/mol

Exact mass

287.13688739 Da

Topological polar surface area

121.0 Ų

Hydrogen-bond donors

5

Hydrogen-bond acceptors

7

Covalent units

2

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

CAS 54-21-7PubChem CID 16760658

Sodium Salicylate

Sodium salicylate is an organic molecular entity. — ChEBI

IUPAC name

sodium 2-hydroxybenzoate

Molecular formula

C7H5NaO3

Molecular weight

160.10 g/mol

Exact mass

160.01363830 Da

Topological polar surface area

60.4 Ų

Hydrogen-bond donors

1

Hydrogen-bond acceptors

3

Covalent units

2

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

CAS 578-36-9PubChem CID 23664627

Potassium Salicylate

The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Potassium Salicylate... — Cosmetic Ingredient Review (CIR)

IUPAC name

potassium 2-hydroxybenzoate

Molecular formula

C7H5KO3

Molecular weight

176.21 g/mol

Exact mass

175.98757550 Da

Topological polar surface area

60.4 Ų

Hydrogen-bond donors

1

Hydrogen-bond acceptors

3

Covalent units

2

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

CAS 59866-70-5PubChem CID 3085170

Salicylic acid monoethanolamine

Based on the available information, the CIR Expert Panel concluded that ... MEA-Salicylate... safe as used when formulated to be avoid skin ittiration and when formulated to avoid increasing the skin's sun sensitivity,or, when increased sun sensitivity would be expected, directions for use induce the daily use of sun protection. — Cosmetic Ingredient Review (CIR)

IUPAC name

2-aminoethanol;2-hydroxybenzoic acid

Molecular formula

C9H13NO4

Molecular weight

199.20 g/mol

Exact mass

199.08445790 Da

Topological polar surface area

104.0 Ų

Hydrogen-bond donors

4

Hydrogen-bond acceptors

5

Covalent units

2

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

CAS 69-72-7PubChem CID 338

Salicylic Acid

Salicylic acid is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. It has a role as an antiinfective agent, an antifungal agent, a plant hormone, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite and an algal metabolite. It is a conjugate acid of a salicylate. — ChEBI

IUPAC name

2-hydroxybenzoic acid

Molecular formula

C7H6O3

Molecular weight

138.12 g/mol

Exact mass

138.031694049 Da

XLogP3

2.3

Topological polar surface area

57.5 Ų

Hydrogen-bond donors

2

Hydrogen-bond acceptors

3

Covalent units

1

Defined stereocentres

0

Also known as

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.