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Annex V Entry 7 15/01/2026

o-Phenylphenol, Sodium o-Phenylphenate

Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate

o-Phenylphenol, Sodium o-Phenylphenate appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: (a) 0,2 % (as phenol (b) 0,15 % (as phenol).

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Permitted preservative— Annex V, EU Regulation 1223/2009
Max conc.: (a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Entry: 7

Chemical identity and properties

PubChem 2D chemical structure for CAS 132-27-4
CAS 132-27-4PubChem CID 23675735

SODIUM o-PHENYLPHENOL

Sodium o-phenylphenoxide is a beige flaky solid. pH of saturated solution in water: 12.0-13.5. (NTP, 1992) — CAMEO Chemicals

IUPAC name
sodium 2-phenylphenolate
Molecular formula
C12H9NaO
Molecular weight
192.19 g/mol
Exact mass
192.05510919 Da
Topological polar surface area
23.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
2
Defined stereocentres
0

Also known as

Sodium o-phenylphenateSodium 2-biphenylateSodium ortho-phenylphenateNatripheneSodium o-phenylphenoxide(1,1'-Biphenyl)-2-ol, sodium saltKFV9K7N7UIsodium phenylphenate
16 more reported names
MICROBAN P 2[1,1'-Biphenyl]-2-ol, sodium saltNSC-1547SODIUM ORTHO-PHENYLPHENATE [IARC](1,1'-Biphenyl)-2-ol, sodium salt (1:1)(1,1'-Biphenyl)-2-ol, sodium salt, tetrahydrate[1,1'-Biphenyl]-2-ol, sodium salt, tetrahydratedowizid2-Hydroxydiphenyl sodium saltSODIUM ORTHO-PHENYLPHENATE (IARC)[1,1'-Biphenyl]-2-ol, sodium salt (1:1)OPP-NA(2-biphenylyloxy)sodiumOPPsodiumMilDuRidSodiumophenylphenol
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 90-43-7
CAS 90-43-7PubChem CID 7017

(1,1'-Biphenyl)-2-ol

Biphenyl-2-ol is a member of the class of hydroxybiphenyls that is biphenyl substituted by a hydroxy group at position 2. It is generally used as a post-harvest fungicide for citrus fruits. It has a role as an environmental food contaminant and an antifungal agrochemical. It derives from a hydride of a biphenyl. — ChEBI

IUPAC name
2-phenylphenol
Molecular formula
C12H10O
Molecular weight
170.21 g/mol
Exact mass
170.073164938 Da
XLogP3
3.1
Topological polar surface area
20.2 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

2-HydroxybiphenylO-PHENYLPHENOLBiphenyl-2-ol2-Biphenylolo-Hydroxybiphenylo-Hydroxydiphenyl2-Hydroxydiphenylo-Phenyl phenol
16 more reported names
Orthoxenol[1,1'-Biphenyl]-2-olOrthophenylphenolDowicide 1o-DiphenylolTorsiteo-XenolNectrylo-BiphenylolPreventol O extraOrthohydroxydiphenylTumescal OPERemol TRFPhenol, o-phenyl-Tetrosin oe2-Fenylfenol
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

(a) 0,2 % (as phenol (b) 0,15 % (as phenol)

Product type

Rinse-off products Leave-on products

Other restrictions

When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products.
Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Warnings

Avoid contact with eyes.

INCI glossary name

o-Phenylphenol, Sodium o-Phenylphenate

Chemical name

Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate

Chemical / IUPAC name

Biphenyl-2-ol

Regulatory information

Regulation

(EU) 2026/78

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
90-43-7, 132-27-4
EC
201-993-5, 205-055-6
Annex
V
Entry number
7

Inventory links for o-Phenylphenol, Sodium o-Phenylphenate

Inventory Restriction reference
Ref 35733

O-PHENYLPHENOL

CAS: 90-43-7
EC: 201-993-5
Annex III 100
Shared product type

TRICLOCARBAN

CAS: 101-20-2
EC: 202-924-1
Annex III 257
Shared product type

LAURETH-9

CAS: 3055-99-0
EC: 221-284-4

What Annex V means for o-Phenylphenol, Sodium o-Phenylphenate

o-Phenylphenol, Sodium o-Phenylphenate is an approved preservative listed in Annex V of EU Cosmetics Regulation 1223/2009. Only substances on this positive list may be used as cosmetic preservatives in the EU.

Each preservative entry specifies maximum permitted concentrations and applicable product scope. Concentrations must not exceed the listed maximum. Some preservatives require warning statements on the product label.

This record is linked to 4 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Use concentration must not exceed: (a) 0,2 % (as phenol (b) 0,15 % (as phenol)
  • Verify the preservative is effective at the permitted concentration for your matrix.
  • Apply required label warning statement.

Frequently asked questions

Yes. o-Phenylphenol, Sodium o-Phenylphenate is listed in Annex V of EU Cosmetics Regulation 1223/2009 as a permitted preservative. It may be used in cosmetics up to the maximum concentration specified above, within the permitted product scope.

CAS 90-43-7, 132-27-4 is the unique numerical identifier assigned to o-Phenylphenol, Sodium o-Phenylphenate by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of (a) 0,2 % (as phenol (b) 0,15 % (as phenol) applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex V record o-Phenylphenol, Sodium o-Phenylphenate

This page summarizes one Annex V record for o-Phenylphenol, Sodium o-Phenylphenate from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex V conditions for o-Phenylphenol, Sodium o-Phenylphenate, but confirm any final regulatory decision against the current official annex wording and source files.

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