Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Annex V Entry 13 16/10/2010

Dehydroacetic acid / SODIUM DEHYDROACETATE

3-Acetyl-6-methylpyran-2,4(3H)-dione and its salts

Dehydroacetic acid / SODIUM DEHYDROACETATE appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: 0.6% (as acid).

Search similar Back to annex Compare Calculate concentration
Permitted preservative— Annex V, EU Regulation 1223/2009
Max conc.: 0.6% (as acid)
Entry: 13

Chemical identity and properties

PubChem 2D chemical structure for CAS 16807-48-0
CAS 16807-48-0CAS 520-45-6PubChem CID 122903

Dehydroacetic acid

Dehydroacetic acid is a pyran-2,4-dione substituted at position 3 by an acetyl group and at position 6 by a methyl group. A fungicide and bactericide it is used primarily in processed fruit and vegetables. It has a role as a fungicide, an antibacterial agent and a plasticiser. It is a pyran-2,4-dione and a ketone. — ChEBI

IUPAC name
3-acetyl-6-methylpyran-2,4-dione
Molecular formula
C8H8O4
Molecular weight
168.15 g/mol
Exact mass
168.04225873 Da
XLogP3
0.3
Topological polar surface area
60.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

520-45-63-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-MethylacetopyrononeBiocide 470FAcetic acid, dehydro-3-Acetyl-6-methyl-2,4-pyrandione3-Acetyl-6-methyl-pyran-2,4-dione
16 more reported names
3-acetyl-6-methyl-3,4-dihydro-2H-pyran-2,4-dioneCHEBI:1374263-Acetyl-6-methylpyrandione-2,4NSC-87702-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid, .delta.-lactone3-acetyl-6-methyl-2,4-dioxo-3H-pyranDehydroacetic acid [ISO]GlyTouCan:G82156FZEpitope ID:613424DTXCID9014Dehydroacetic acid (Standard)HY-B1211RPGRHXDWITVMQBC-UHFFFAOYSA-MSK2505NSC87704-Hexenoic acid, .delta.-lactone
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 4418-26-2
CAS 4418-26-2PubChem CID 23721629

Sodium Dehydroacetate

Sodium dehydroacetate is a white powder. Used as a fungicide, plasticizer, toothpaste, preservative in food. — CAMEO Chemicals

IUPAC name
sodium 3-acetyl-6-methylpyran-3-ide-2,4-dione
Molecular formula
C8H7NaO4
Molecular weight
190.13 g/mol
Exact mass
190.02420298 Da
Topological polar surface area
60.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
5
Covalent units
2
Defined stereocentres
0

Also known as

HarvenDHA-sodiumPrevanNew Side S 01Dehydroacetic acid, sodium saltDHA-SSodium Dehydroacetic AcidSodium 3-acetyl-6-methyl-2,4-pyrandione
16 more reported names
Kyselina dehydroacetova sodna sul2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, ion(1-), sodium8W46YN971GSodium 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium salt2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, sodium salt2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, monosodium salt3-(1-Hydroxyethylidene)-6-methyl-2H-pyran-2,4(3H)-dione, sodium salt4-Hexenoic acid, 2-acetyl-5-hydroxy-3-oxo, delta-lactone, sodium derivativeRefChem:183852sodium 3-acetyl-6-methyl-4-oxo-4H-pyran-2-olate224-580-1sodium 3-acetyl-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-idedehydroacetic acid sodiumSodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolateDehydroacetic acid (sodium)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

0.6% (as acid)

Other restrictions

Not to be used in aerosol dispensers (sprays)

INCI glossary name

Dehydroacetic acid / SODIUM DEHYDROACETATE

Chemical name

3-Acetyl-6-methylpyran-2,4(3H)-dione and its salts

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Identified ingredients

Key data

CAS
520-45-6 / 4418-26-2 / 16807-48-0
EC
208-293-9 / 224-580-1 / -
Annex
V
Entry number
13

Inventory links for Dehydroacetic acid / SODIUM DEHYDROACETATE

Inventory Restriction reference
Ref 33185

DEHYDROACETIC ACID

CAS: 520-45-6 / 771-03-9 / 16807-48-0
EC: 208-293-9 / 212-227-4 / -

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 11
Nearby record in the same annex

CHLOROBUTANOL

CAS: 57-15-8
EC: 200-317-6
Annex V 16
Nearby record in the same annex

THIMEROSAL

CAS: 54-64-8
EC: 200-210-4
Annex V 19
Nearby record in the same annex

Hexetidine

CAS: 141-94-6
EC: 205-513-5

What Annex V means for Dehydroacetic acid / SODIUM DEHYDROACETATE

Dehydroacetic acid / SODIUM DEHYDROACETATE is an approved preservative listed in Annex V of EU Cosmetics Regulation 1223/2009. Only substances on this positive list may be used as cosmetic preservatives in the EU.

Each preservative entry specifies maximum permitted concentrations and applicable product scope. Concentrations must not exceed the listed maximum. Some preservatives require warning statements on the product label.

This record is linked to 2 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Use concentration must not exceed: 0.6% (as acid)
  • Verify the preservative is effective at the permitted concentration for your matrix.

Frequently asked questions

Yes. Dehydroacetic acid / SODIUM DEHYDROACETATE is listed in Annex V of EU Cosmetics Regulation 1223/2009 as a permitted preservative. It may be used in cosmetics up to the maximum concentration specified above, within the permitted product scope.

CAS 520-45-6 / 4418-26-2 / 16807-48-0 is the unique numerical identifier assigned to Dehydroacetic acid / SODIUM DEHYDROACETATE by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

The maximum concentration of 0.6% (as acid) applies to the concentration of the substance in the ready-to-use cosmetic product. When the substance is supplied as part of a blend or mixture, the calculation must account for the contribution of all sources in the formulation. The combined concentration must not exceed the stated limit.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
Open INCI Checker

Source note for Annex V record Dehydroacetic acid / SODIUM DEHYDROACETATE

This page summarizes one Annex V record for Dehydroacetic acid / SODIUM DEHYDROACETATE from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex V conditions for Dehydroacetic acid / SODIUM DEHYDROACETATE, but confirm any final regulatory decision against the current official annex wording and source files.

View sourcesView updates

Tools & next steps

Check your formula

Paste a full INCI list to detect Dehydroacetic acid / SODIUM DEHYDROACETATE and other flagged EU annex records in one pass.

INCI Checker

Compare entries

Compare Dehydroacetic acid / SODIUM DEHYDROACETATE side by side with another annex record to review differences in restrictions, concentrations and annex placement.

Compare

Browse the annex

See all records in Annex V and compare regulatory conditions across substances in this annex.

Open Annex V