Annex V Entry 2 16/10/2010

PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE

Q: How is the maximum concentration of PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE calculated in a finished product?

The maximum concentration of 2% (acid) applies to the substance in the ready-to-use cosmetic product. When supplied as part of a blend or mixture, the calculation must account for contributions from all sources in the formulation.

Q: How do I check if my product formula contains PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE?

Use the INCI Checker tool on CosIng Checker to paste your full ingredient list and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records.

Propionic acid and its salts

PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: 2% (acid).

Permitted preservative— Annex V, EU Regulation 1223/2009

Max conc.: 2% (acid)

Entry: 2

Chemical identity and properties

PubChem 2D chemical structure for CAS 137-40-6

CAS 137-40-6PubChem CID 2723816

Sodium Propionate

Sodium propionate is an organic sodium salt comprising equal numbers of sodium and propionate ions. It has a role as a food preservative and an antifungal drug. It contains a propionate. — ChEBI

IUPAC name: sodium propanoate

Molecular formula: C3H5NaO2
Molecular weight: 96.06 g/mol
Exact mass: 96.01872368 Da
Topological polar surface area: 40.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 2
Defined stereocentres: 0

Also known as

Propionic acid sodium saltPropanoic acid, sodium saltOcuseptineNapropionPropisolPropionic acid, sodium saltBioban-SPropiofar

16 more reported names

DeketonImpedexKeenateMycobanNatriumpropionatPropi-ophtalSodium propionate anhydrousWhit-proPropanoic acid, sodium salt (1:1)Propionan sodnyDK6Y9P42INE281INS NO.281CHEBI:132106INS-281391O0PO49R

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:132106
ChEMBL:CHEMBL500826
EPA DTXSID:DTXSID7021996
PubMed:37269894
PubMed:35639301
PubMed:31621310
PubMed:1597404

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 17496-08-1

CAS 17496-08-1PubChem CID 87139

Ammonium propionate

IUPAC name: azane;propanoic acid

Molecular formula: C3H9NO2
Molecular weight: 91.11 g/mol
Exact mass: 91.063328530 Da
Topological polar surface area: 38.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Propanoic acid, ammonium saltPropanoic acid, ammonium salt (1:1)V18VR2SK15RefChem:1076673241-503-7UNII-V18VR2SK15amine propionateEINECS 241-503-7

3 more reported names

ammonia;propionic acidPropanoic acid--ammonia (1/1)XJMWHXZUIGHOBA-UHFFFAOYSA-N

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID9066207

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 327-62-8

CAS 327-62-8PubChem CID 23663619

Potassium propionate

IUPAC name: potassium propanoate

Molecular formula: C3H5KO2
Molecular weight: 112.17 g/mol
Exact mass: 111.99266088 Da
Topological polar surface area: 40.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 2
Defined stereocentres: 0

Also known as

7H1F04CKTXINS NO. 283INS-283E-283RefChem:175586206-323-5Propionic Acid Potassium SaltPropanoic acid, potassium salt

13 more reported names

potassium;propanoateUNII-7H1F04CKTXPotassium propionate, AldrichCPRP0510potassium,propanoatePROPIONICACIDPOTASSIUMSALTEINECS 206-323-5C3H5KO2TN9419PROPIONIC ACID, POTASSIUM SALTAS-59778FT-063195CS-0019431

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID50186368

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 4075-81-4

CAS 4075-81-4PubChem CID 19999

Calcium propionate

IUPAC name: calcium propanoate

Molecular formula: C6H10CaO4
Molecular weight: 186.22 g/mol
Exact mass: 186.0204996 Da
Topological polar surface area: 80.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 3
Defined stereocentres: 0

Also known as

Propanoic acid, calcium saltBioban-CPropionic acid, calcium saltPropanoic acid, calcium salt (2:1)8AI80040KWINS NO.282INS-282E-282

16 more reported names

RefChem:122900223-795-8Calcium dipropionatecalcium;propanoatepropionic acid calciumPropionic acid calcium saltPropanoate (calcium)Calcium propionate [NF]calcium dipropanoateCalcium propionate;Bioban-C; Calcium dipropionateCaswell No. 151HSDB 907EINECS 223-795-8EPA Pesticide Chemical Code 077701C6H10CaO4UNII-8AI80040KW

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External database identifiers

ChEMBL:CHEMBL3186661
EPA DTXSID:DTXSID1027556
PubMed:37045926
PubMed:34208526
PubMed:32179172
PubMed:32113756
PubMed:31333813
PubMed:29477151
PubMed:9710771
PubMed:8708097

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 557-27-7

CAS 557-27-7PubChem CID 6453238

Magnesium propionate

IUPAC name: magnesium propanoate

Molecular formula: C6H10MgO4
Molecular weight: 170.45 g/mol
Exact mass: 170.0429505 Da
Topological polar surface area: 80.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 3
Defined stereocentres: 0

Also known as

Magnesium dipropionateUNII-699E2A173PEINECS 209-166-0699E2A173PPROPANOIC ACID, MAGNESIUM SALTPROPIONIC ACID, MAGNESIUM SALTRefChem:155255MAGNESIUM PROPIONATE [INCI]

3 more reported names

magnesium;propanoateMagnesium dipropanoateDB-209015

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90204232

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 79-09-4

CAS 79-09-4PubChem CID 1032

Propionic Acid

Propionic acid is a short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group. It has a role as an antifungal drug. It is a saturated fatty acid and a short-chain fatty acid. It is a conjugate acid of a propionate. — ChEBI

IUPAC name: propanoic acid

Molecular formula: C3H6O2
Molecular weight: 74.08 g/mol
Exact mass: 74.036779430 Da
XLogP3: 0.3
Topological polar surface area: 37.3 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

methylacetic acidethylformic acidCarboxyethaneMetacetonic acidLuprosilEthanecarboxylic acidPseudoacetic acidMonoprop

16 more reported names

ProzoinAntischim BPropionoic acidMethyl acetic acidAcide propioniqueSentry grain preserverPropcornPropkornC3 acidTenox P grain preservativeCaswell No. 707AdofeedPropionic acid grain preserverFEMA No. 2924Kyselina propionovaFEMA Number 2924

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:30768
ChEMBL:CHEMBL14021
EPA DTXSID:DTXSID8025961
PubMed:23124754
PubMed:23060857
PubMed:23044120
PubMed:23043820
PubMed:23039985
PubMed:23032783
PubMed:23031469
PubMed:23030718
PubMed:23021520
PubMed:23007062
PubMed:23002626
PubMed:22978585

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

2% (acid)

INCI glossary name

PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE

Chemical name

Propionic acid and its salts

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

Opinion concerning Restrictions on Materials listed in annex VI of Directive 76/768/EEC on Cosmetic Products

Identified ingredients

Key data

CAS

79-09-4 / 17496-08-1 / 4075-81-4 / 557-27-7 / 327-62-8 / 137-40-6

201-176-3 / 241-503-7 / 223-795-8 / 209-166-0 / 206-323-5 / 205-290-4

Annex

Entry number

Inventory links for PROPIONIC ACID / AMMONIUM PROPIONATE / CALCIUM PROPIONATE / MAGNESIUM PROPIONATE / POTASSIUM PROPIONATE / SODIUM PROPIONATE

Inventory Restriction reference

Ref 31896

AMMONIUM PROPIONATE

CAS: 17496-08-1

EC: 241-503-7

Inventory Restriction reference

Ref 32341

CALCIUM PROPIONATE

CAS: 4075-81-4

EC: 223-795-8

Inventory Restriction reference

Ref 35116

MAGNESIUM PROPIONATE

CAS: 557-27-7

EC: 209-166-0

Inventory Restriction reference

Ref 37018

POTASSIUM PROPIONATE

CAS: 327-62-8

EC: 206-323-5

Inventory Restriction reference

Ref 37261

PROPIONIC ACID

CAS: 79-09-4

EC: 201-176-3

Inventory Restriction reference

Ref 38042

SODIUM PROPIONATE

CAS: 137-40-6

EC: 205-290-4

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 1