What does the restriction note for SODIUM SALICYLATE mean?

The restriction field for SODIUM SALICYLATE reads: V/3. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 54-21-7?

CAS 54-21-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SODIUM SALICYLATE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3805211/08/2020

SODIUM SALICYLATE

Sodium salicylate

SODIUM SALICYLATE is linked to 2 EU annex records on this page. Inventory note: V/3.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	2	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 54-21-7

CAS 54-21-7PubChem CID 16760658

Sodium Salicylate

Sodium salicylate is an organic molecular entity. — ChEBI

IUPAC name: sodium 2-hydroxybenzoate

Molecular formula: C7H5NaO3
Molecular weight: 160.10 g/mol
Exact mass: 160.01363830 Da
Topological polar surface area: 60.4 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

EnterosalicylKerasalicylAlysineBenzoic acid, 2-hydroxy-, monosodium saltNatrum salicylicumSalicylic acid sodium saltsalicylate sodiumMonosodium 2-hydroxybenzoate

16 more reported names

Natrii salicylasWIQ1H85SYPSalicylate, sodiumNSC-202167Benzoic acid, 2-hydroxy-, sodium salt (1:1)Sod salPro-PrinSaliGard 60RefChem:6246UNI-SOLUNI-SOL 60Aspen Sodium Salicylate 48.6%AquaPrime Liquid Sodium SalicylateAquasource Aqua-Prin Water Soluble Sodium Salicylate200-198-0Salsonin

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:9180
ChEMBL:CHEMBL447868
EPA DTXSID:DTXSID5021708
PubMed:29117515
PubMed:23652544
PubMed:23504962
PubMed:22898132
PubMed:21303813
PubMed:19767084
PubMed:19173110
PubMed:19026709
PubMed:18560754
PubMed:18483001
PubMed:17568627
PubMed:17561093

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SODIUM SALICYLATE

INCI name

SODIUM SALICYLATE

INN name

sodium salicylate

Ph. Eur. name

natrii salicylas

Description

Sodium salicylate

Record provenance

Inventory reference: 38052
Imported identity: SODIUM SALICYLATE
Source update: 11/08/2020

European Commission CosIng source notes

Annex records for SODIUM SALICYLATE

Annex III Identified ingredient

Entry 98

SALICYLIC ACID

CAS: 69-72-7

EC: 200-712-3

Annex V Restriction reference

Entry 3

SALICYLIC ACID, CALCIUM SALICYLATE, MAGNESIUM SALICYLATE, MEA- SALICYLATE, SODIUM SALICYLATE, POTAS…

CAS: 69-72-7[1]/ 824-35-1[2]/ 18917-89-0[3]/ 59866-70-5[4]/ 54-21-7[5]/ 578-36-9[6]/ 2174-16-5[7]

EC: 200-712-3[1]/ 212-525-4[2]/ 242-669-3[3]/ 261-963-2[4]/ 200-198-0[5]/ 209-421-6[6]/ 218-531-3[7]

Key data

CAS

54-21-7

200-198-0

Restriction

V/3

Function

DENATURANT: Rendering cosmetics unpalatable. Mostly added to cosmetics containing ethyl alcohol to make it unsuitable for ingestion.
PRESERVATIVE: Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#26976 · SODIUM SALICYLATE

Ingredients with overlapping formulation functions

SODIUM 3-MERCAPTOPROPANE SULFONATEDENATURANT, HAIR CONDITIONING, pH ADJUSTERS, SURFACE MODIFIER

SODIUM HYDROXIDEBUFFERING, DENATURANT

SODIUM LAURYL SULFATECLEANSING, DENATURANT, FOAMING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

SODIUM MENTHYL SUCCINATEASTRINGENT, DENATURANT, FLAVOURING, ORAL CARE

SUCROSE OCTAACETATEDENATURANT, FRAGRANCE

T-BUTYL ALCOHOLDENATURANT, PERFUMING, SOLVENT

THYMOLDENATURANT, FRAGRANCE, HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SODIUM SALICYLATE appears in the CosIng inventory

The CosIng inventory lists SODIUM SALICYLATE as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM SALICYLATE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM SALICYLATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for SODIUM SALICYLATE reads: "V/3". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, SODIUM SALICYLATE carries the following function designation(s):

CAS 54-21-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SODIUM SALICYLATE

This page combines the CosIng inventory entry for SODIUM SALICYLATE with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research SODIUM SALICYLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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