Annex V Entry 12 a 02/08/2021

BUTYLPARABEN/PROPYLPARABEN/SODIUM PROPOYLPARABEN/SODIUM BUTYLPARABEN/POTASSIUM BUTYLPARABEN/POTASSIUM PROPYLPARABEN

Q: How do I check if my product formula contains BUTYLPARABEN/PROPYLPARABEN/SODIUM PROPOYLPARABEN/SODIUM BUTYLPARABEN/POTASSIUM BUTYLPARABEN/POTASSIUM PROPYLPARABEN?

Use the INCI Checker tool on CosIng Checker to paste your full ingredient list and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records.

Butyl 4-hydroxybenzoate and its salts Propyl 4-hydroxybenzoate and its salts

BUTYLPARABEN/PROPYLPARABEN/SODIUM PROPOYLPARABEN/SODIUM BUTYLPARABEN/POTASSIUM BUTYLPARABEN/POTASSIUM PROPYLPARABEN appears in Annex V as a positive-list preservative entry for EU cosmetics. Maximum concentration in this record: - 0,14% (as acid) for the sum of the individual concentrations - 0,8% (as acid) for mixtures of substances mentioned in entry 12 and 12a, here the sum of the individual concentrations of butyl and propylparaben and their salts does not exceed 0,14%.

Permitted preservative— Annex V, EU Regulation 1223/2009

Entry: 12 a

Chemical identity and properties

PubChem 2D chemical structure for CAS 35285-69-9

CAS 35285-69-9PubChem CID 23679044

Propylparaben Sodium

The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Sodium Propylparaben... — Cosmetic Ingredient Review (CIR)

IUPAC name: sodium 4-propoxycarbonylphenolate

Molecular formula: C10H11NaO3
Molecular weight: 202.18 g/mol
Exact mass: 202.06058849 Da
Topological polar surface area: 49.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Sodium propylparabenPropyl 4-hydroxybenzoate sodium saltSodium propyl 4-hydroxybenzoateCaswell No. 714APropyl p-hydroxybenzoate, sodium saltsodium propyl parabenSodium propyl hydroxybenzoatePropylparaben sodium [USAN]

16 more reported names

Natrium propyl 4-hydroxybenzoatSodium Propyl ParahydroxybenzoatePropylparaben, sodium saltPropyl-4-hydroxybenzoat natriumsalzEINECS 252-488-1UNII-625NNB0G9NEPA Pesticide Chemical Code 061204625NNB0G9NPropylparaben sodium [USAN:NF]Propylparaben sodium (NF)SODIUM PROPYL HYDROXYBENZOATE [MART.]PROPYLPARABEN SODIUM [II]4-Hydroxybenzoic acid, propyl ester, sodium saltSODIUM PROPYL PARAHYDROXYBENZOATE [EP MONOGRAPH]SODIUM PROPYL P-HYDROXYBENZOATE (E 217)PROPYLPARABEN SODIUM (II)

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External database identifiers

ChEMBL:CHEMBL2107021
EPA DTXSID:DTXSID3042348

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 36457-20-2

CAS 36457-20-2PubChem CID 23671890

Butylparaben Sodium

The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Sodium Butylparaben... — Cosmetic Ingredient Review (CIR)

IUPAC name: sodium 4-butoxycarbonylphenolate

Molecular formula: C11H13NaO3
Molecular weight: 216.21 g/mol
Exact mass: 216.07623855 Da
Topological polar surface area: 49.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Butyl 4-hydroxybenzoate sodium saltSodium butylparabenSodium butyl 4-hydroxybenzoateButyl p-hydroxybenzoate sodiumSodium butyl hydroxybenzoateButyl-4-hydroxybenzoate sodium saltEINECS 253-049-7MAR76J77VS

16 more reported names

BENZOIC ACID, p-HYDROXY-, BUTYL ESTER, SODIUM SALTBUTYL PARAHYDROXYBENZOATE SODIUMSODIUM BUTYL HYDROXYBENZOATE [MART.]P-HYDROXYBENZOIC ACID BUTYL ESTER SODIUM SALTBENZOIC ACID, 4-HYDROXY-, BUTYL ESTER, SODIUM SALT (1:1)SODIUM BUTYL HYDROXYBENZOATE (MART.)RefChem:571867SODIUM BUTYLPARABEN [INCI]Butylparaben sodium saltsodium;4-butoxycarbonylphenolateSodium 4-(butoxycarbonyl)phenolateButylparaben (sodium)UNII-MAR76J77VSMSK2512NaC11H13NaO3HY-B1431A

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External database identifiers

EPA DTXSID:DTXSID10189971

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 38566-94-8

CAS 38566-94-8PubChem CID 23663689

Potassium Butylparaben

The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Potassium Butylparaben... — Cosmetic Ingredient Review (CIR)

IUPAC name: potassium 4-butoxycarbonylphenolate

Molecular formula: C11H13KO3
Molecular weight: 232.32 g/mol
Exact mass: 232.05017576 Da
Topological polar surface area: 49.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

UNII-PGG48E5PSXPGG48E5PSXEINECS 254-009-1BUTYLPARABEN, POTASSIUM SALTP-HYDROXYBENZOATE POTASSIUM SALTBENZOIC ACID, 4-HYDROXY-, BUTYL ESTER, POTASSIUM SALTBENZOIC ACID, 4-HYDROXY-, BUTYL ESTER, POTASSIUM SALT (1:1)RefChem:175435

7 more reported names

POTASSIUM BUTYLPARABEN [INCI]Potassium butyl 4-oxidobenzoatepotassium;4-butoxycarbonylphenolatePotassium Butyl 4-hydroxybenzoateMSK2512KDPMDQHINTKFMKS-UHFFFAOYSA-MPotassium 4-(butoxycarbonyl)phenolate

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External database identifiers

EPA DTXSID:DTXSID90191890

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 84930-16-5

CAS 84930-16-5PubChem CID 23662516

Potassium Propylparaben

The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Potassium Propylparaben... — Cosmetic Ingredient Review (CIR)

IUPAC name: potassium 4-propoxycarbonylphenolate

Molecular formula: C10H11KO3
Molecular weight: 218.29 g/mol
Exact mass: 218.03452569 Da
Topological polar surface area: 49.4 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Potassium propyl 4-oxidobenzoateUNII-9THL6FXS4I9THL6FXS4IEINECS 284-597-5Benzoic acid, 4-hydroxy-, propyl ester, potassium saltBENZOIC ACID, 4-HYDROXY-, PROPYL ESTER, POTASSIUM SALT (1:1)RefChem:175587POTASSIUM PROPYLPARABEN [INCI]

8 more reported names

propylparaben potassiumPROPYL-4-HYDROXYBENZOATE, POTASSIUM SALTMSK2511KTUMYXYVXTFDMTJ-UHFFFAOYSA-MPotassium propyl 4-hydroxybenzoateEBC-76138potassium 4-(propoxycarbonyl)phenolatePotassium Propyl 4-Hydroxybenzoate Solution, 100pm

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External database identifiers

EPA DTXSID:DTXSID80233975

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 94-13-3

CAS 94-13-3PubChem CID 7175

Propylparaben

Propylparaben is the benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive. It has a role as an antimicrobial agent and an antifungal agent. It is a member of phenols, a benzoate ester and a paraben. It is functionally related to a propan-1-ol and a 4-hydroxybenzoic acid. — ChEBI

IUPAC name: propyl 4-hydroxybenzoate

Molecular formula: C10H12O3
Molecular weight: 180.20 g/mol
Exact mass: 180.078644241 Da
XLogP3: 3.0
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Propyl parabenNipasolPropyl p-hydroxybenzoateNipazolPropagin4-Hydroxybenzoic acid propyl esterPropyl parahydroxybenzoateTegosept P

16 more reported names

Nipagin PPropyl ButexBetacide PNipasol PChemocide pkPropyl ParaseptAseptoform PPropyl ChemoseptSolbrol PPropylparaseptn-Propyl 4-hydroxybenzoatePaseptolChemacide pkPreserval PBetacine PN-Propyl p-hydroxybenzoate

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External database identifiers

ChEBI:CHEBI:32063
ChEMBL:CHEMBL194014
EPA DTXSID:DTXSID4022527
PubMed:23056216
PubMed:23037998
PubMed:23028405
PubMed:22814205
PubMed:22790701
PubMed:22640822
PubMed:22606064
PubMed:22606022
PubMed:22594253
PubMed:22523455
PubMed:22518310
PubMed:22470890

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 94-26-8

CAS 94-26-8PubChem CID 7184

Butylparaben

Butylparaben is an organic molecular entity. — ChEBI

IUPAC name: butyl 4-hydroxybenzoate

Molecular formula: C11H14O3
Molecular weight: 194.23 g/mol
Exact mass: 194.094294304 Da
XLogP3: 3.6
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Butyl parabenButyl p-hydroxybenzoateButobenNipabutylButyl chemoseptButyl paraseptTegosept BButyl tegosept

16 more reported names

Butyl butexAseptoform butylSolbrol BButyl parahydroxybenzoaten-Butyl p-hydroxybenzoateTegosept ButylPreserval BButyl-ParaseptBenzoic acid, 4-hydroxy-, butyl esterbutyl p-hydroxy benzoate4-(Butoxycarbonyl)phenolButyl hydroxybenzoaten-butyl 4-hydroxybenzoaten-Butyl parahydroxybenzoaten-Butyl hydroxybenzoatep-Hydroxybenzoic acid butyl ester

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External database identifiers

ChEBI:CHEBI:88542
ChEMBL:CHEMBL459008
EPA DTXSID:DTXSID3020209
PubMed:39778647
PubMed:39532263
PubMed:37690743
PubMed:37632306
PubMed:36277366
PubMed:35470536
PubMed:34383603
PubMed:32798586
PubMed:31472229
PubMed:31016361
PubMed:30940137
PubMed:30817981

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Maximum concentration

- 0,14% (as acid) for the sum of the individual concentrations - 0,8% (as acid) for mixtures of substances mentioned in entry 12 and 12a, here the sum of the individual concentrations of butyl and propylparaben and their salts does not exceed 0,14%

Other restrictions

Not to be used in leave-on products designed for application on the nappy area of children under three years of age.

Warnings

For leave-on products designed for children under three years of age: "Do not use on the nappy area"

INCI glossary name

BUTYLPARABEN/PROPYLPARABEN/SODIUM PROPOYLPARABEN/SODIUM BUTYLPARABEN/POTASSIUM BUTYLPARABEN/POTASSIUM PROPYLPARABEN

Chemical name

Butyl 4-hydroxybenzoate and its salts Propyl 4-hydroxybenzoate and its salts

Chemical / IUPAC name

Butyl 4-hydroxybenzoate and its salts Propyl 4-hydroxybenzoate and its salts (Butylparaben, propylparaben, sodium propylparaben, sodium butylparaben, potassium butylparaben, potassium propylparaben)

Regulatory information

Regulation

(EC) 2014/1004

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS

94-26-8/ 94-13-3/ 35285-69-9/ 36457-20-2/ 38566-94-8/ 84930-16-5

202-318-7/ 202-307-7/ 252-488-1/ 253-049-7/ 254-009-1/ 284-597-5

Annex

Entry number

12 a

Inventory links for BUTYLPARABEN/PROPYLPARABEN/SODIUM PROPOYLPARABEN/SODIUM BUTYLPARABEN/POTASSIUM BUTYLPARABEN/POTASSIUM PROPYLPARABEN

Inventory Identified ingredient

Ref 31734

BUTYLPARABEN

CAS: 94-26-8

EC: 202-318-7

Inventory Identified ingredient

Ref 36938

POTASSIUM BUTYLPARABEN

CAS: 38566-94-8

EC: 254-009-1

Inventory Identified ingredient

Ref 37019

POTASSIUM PROPYLPARABEN

CAS: 84930-16-5

EC: 284-597-5

Inventory Identified ingredient

Ref 37312

PROPYLPARABEN

CAS: 94-13-3

EC: 202-307-7

Inventory Identified ingredient

Ref 37746

SODIUM BUTYLPARABEN

CAS: 36457-20-2

EC: 253-049-7

Inventory Identified ingredient

Ref 38044

SODIUM PROPYLPARABEN

CAS: 35285-69-9

EC: 252-488-1

Direct matches are limited for this record, so nearby entries from Annex V are shown as well.

Annex V 11