| II | 400 | 1,2-Epoxybutane | 15/10/2010 |
| II | 401 | Colouring agent CI 15585 | 09/06/2015 |
| II | 402 | Strontium lactate | 15/10/2010 |
| II | 403 | Strontium nitrate | 15/10/2010 |
| II | 404 | Strontium polycarboxylate | 15/10/2010 |
| II | 405 | Pramocaine (INN) | 20/10/2010 |
| II | 406 | 4-Ethoxy-m-phenylenediamine and its salts | 15/10/2010 |
| II | 407 | 2,4-Diaminophenylethanol and its salts | 20/10/2010 |
| II | 408 | Pyrocatechol (Catechol) | 20/10/2010 |
| II | 409 | Pyrogallol | 15/10/2010 |
| II | 41 | Apocynum cannabium L. and its preparations | 15/10/2010 |
| II | 410 | Nitrosamines e.g. Dimethylnitrosoamine; Nitrosodipropylamine; 2,2'-(Nitrosoimino)bisethanol | 07/01/2011 |
| II | 411 | Secondary alkyl- and alkanolamines and their salts | 15/10/2010 |
| II | 412 | 4-Amino-2-nitrophenol | 20/10/2010 |
| II | 413 | 2-Methyl-m-phenylenediamine (Toluene-2,6-diamine) | 20/10/2010 |
| II | 414 | 4-tert.-Butyl-3-methoxy-2,6-dinitrotoluene (Musk ambrette) | 20/10/2010 |
| II | 416 | Cells, tissues or products of human origin | 20/01/2023 |
| II | 417 | 3,3-Bis(4-hydroxyphenyl)phthalide (Phenolphthalein (INN)) | 07/01/2011 |
| II | 418 | 3-Imidazol-4-ylacrylic acid (Urocanic acid) and its ethyl ester | 20/10/2010 |
| II | 419 | Category 1 material and Category 2 material as defined in Articles 4 and 5 respectively of Regulation (EC) No… | 20/10/2010 |
| II | 42 | Apomorphine ((R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol)) and its salts | 17/10/2010 |
| II | 420 | Crude and refined coal tars | 15/10/2010 |
| II | 421 | 1,1,3,3,5-Pentamethyl-4,6-dinitroindane (Moskene) | 15/10/2010 |
| II | 422 | 5-tert.-Butyl-1,2,3-trimethyl-4,6-dinitrobenzene (Musk Tibetene) | 20/10/2010 |
| II | 423 | Alanroot oil (Inula helenium L.) (CAS No 97676-35-2), when used as a fragrance ingredient | 20/10/2010 |
| II | 424 | Benzyl cyanide, when used as a fragrance ingredient | 20/10/2010 |
| II | 425 | Cyclamen alcohol, when used as a fragrance ingredient | 01/10/2025 |
| II | 426 | Diethyl maleate, when used as a fragrance ingredient | 20/10/2010 |
| II | 427 | 3,4-Dihydrocoumarin, when used as a fragrance ingredient | 20/10/2010 |
| II | 428 | 2,4-Dihydroxy-3-methylbenzaldehyde, when used as a fragrance ingredient | 20/10/2010 |
| II | 429 | 3,7-Dimethyl-2-octen-1-ol (6,7-Dihydrogeraniol), when used as a fragrance ingredient | 30/01/2023 |
| II | 43 | Arsenic and its compounds | 07/01/2011 |
| II | 430 | 4,6-Dimethyl-8-tert-butylcoumarin, when used as a fragrance ingredient | 20/10/2010 |
| II | 431 | Dimethyl citraconate, when used as a fragrance ingredient | 20/10/2010 |
| II | 432 | 7,11-Dimethyl-4,6,10-dodecatrien-3-one (Pseudomethylionone), when used as a fragrance ingredient | 20/10/2010 |
| II | 433 | 6,10-Dimethyl-3,5,9-undecatrien-2-one (Pseudoionone), when used as a fragrance ingredient | 20/10/2010 |
| II | 434 | Diphenylamine, when used as a fragrance ingredient | 20/10/2010 |
| II | 435 | Ethyl acrylate, when used as a fragrance ingredient | 20/10/2010 |
| II | 436 | Fig leaf absolute (Ficus carica L.), when used as a fragrance ingredient | 20/10/2010 |
| II | 437 | trans-2-Heptenal, when used as a fragrance ingredient | 20/10/2010 |
| II | 438 | trans-2-Hexenal diethyl acetal, when used as a fragrance ingredient | 20/10/2010 |
| II | 439 | trans-2-Hexenal dimethyl acetal, when used as a fragrance ingredient | 20/10/2010 |
| II | 44 | Atropa belladonna L. and its preparations | 15/10/2010 |
| II | 440 | Hydroabietyl alcohol, when used as a fragrance ingredient | 03/08/2020 |
| II | 441 | 6-Isopropyl-2-decahydronaphthalenol, when used as a fragrance ingredient | 20/10/2010 |
| II | 442 | 7-Methoxycoumarin, when used as a fragrance ingredient | 20/10/2010 |
| II | 443 | 4-(4-Methoxyphenyl)-3-butene-2-one (Anisylidene acetone), when used as a fragrance ingredient | 20/10/2010 |
| II | 444 | 1-(4-Methoxyphenyl)-1-pentene-3-one (alpha-Methylanisylideneacetone), when used as a fragrance ingredient | 20/10/2010 |
| II | 445 | Methyl trans-2-butenoate, when used as a fragrance ingredient | 20/10/2010 |
| II | 446 | 7-Methylcoumarin, when used as a fragrance ingredient | 20/10/2010 |